Analysis of new potential anticonvulsant compounds in mice brain tissue by SPE/HPLC/DAD

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 909, Issue , 2012, Pages 26-33

  Flieger, Jolanta ^a   Pizoń, Magdalena ^a   Plech, Tomasz ^a   Łuszczki, Jarogniew J ^a,b  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b INSTITUTE OF AGRICULTURAL MEDICINE   (Poland)

Author keywords

Anti epileptic agents; DAD; HPLC; Mouse brain tissue; SPE

Indexed keywords

2-PROPANOL; AGILENT TECHNOLOGIES; ANALYTES; ANTIEPILEPTIC DRUGS; ARRAY DETECTION; BODY WEIGHT; BRAIN TISSUE; CARBAMAZEPINE; DAD; DEGRADATION STUDY; EXTRACTION YIELD; GRADIENT ELUTION MODE; HPLC; ISOCRATIC ELUTION; LINEAR COEFFICIENTS; MOBILE PHASE; MOUSE BRAIN; OCTADECYL; PHARMACOLOGICAL ACTIVITY; PHENYTOIN; RELATIVE STANDARD DEVIATIONS; REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; SAMPLE PREPARATION PROCEDURE; SOLID PHASE EXTRACTION METHOD; SPE; SYNERGISTIC ACTIVITY;

ACETONITRILE; AMIDES; BRAIN; DIODES; METHANOL;

MAMMALS;

1,2,4 TRIAZOLE DERIVATIVE; 2 PROPANOL; ANTICONVULSIVE AGENT; CARBAMAZEPINE; METHANOL; PHENOBARBITAL; PHENYTOIN; TP 315; TP 321; TP 323; UNCLASSIFIED DRUG;

ANALYSIS; ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN TISSUE; CALIBRATION; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENTIATION; DRUG STRUCTURE; MOUSE; NONHUMAN; PHOTODIODE ARRAY DETECTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID PHASE EXTRACTION;

ANIMALS; ANTICONVULSANTS; BRAIN CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MICE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TRIAZOLES;

MUS;

EID: 84868231116     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.10.011     Document Type: Article

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