The effect of caffeine on retinal vessel diameter in young healthy subjects

Acta Ophthalmologica

Volumn 90, Issue 7, 2012, Pages

  Terai, Naim ^a   Spoerl, Eberhard ^a   Pillunat, Lutz E ^a   Stodtmeister, Richard ^a  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

caffeine; retinal arterioles; retinal venules; retinal vessel analyzer; retinal vessel diameter

Indexed keywords

CAFFEINE;

ADULT; ARTERIOLE; ARTICLE; BLOOD PRESSURE MEASUREMENT; CORRELATION ANALYSIS; DIETARY INTAKE; FEMALE; HUMAN; HUMAN EXPERIMENT; INTRAOCULAR PRESSURE; MALE; MEAN ARTERIAL PRESSURE; NORMAL HUMAN; NUTRITIONAL ASSESSMENT; PERFUSION PRESSURE; PHOTOSTIMULATION; PRIORITY JOURNAL; RETINA BLOOD VESSEL; VASOCONSTRICTION; VENULE; VISUAL SYSTEM PARAMETERS;

ADULT; BLOOD PRESSURE; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; FEMALE; HEART RATE; HUMANS; INTRAOCULAR PRESSURE; MALE; PHOTIC STIMULATION; REGIONAL BLOOD FLOW; RETINAL ARTERY; RETINAL VEIN; VASOCONSTRICTION; YOUNG ADULT;

EID: 84868213547     PISSN: 1755375X     EISSN: 17553768     Source Type: Journal    
DOI: 10.1111/j.1755-3768.2012.02486.x     Document Type: Article

References (31)

1. Adams BA, &, Brubaker RF, (1990): Caffeine has no clinically significant effect on aqueous humor flow in the normal eye. Ophthalmology 97: 1030-1031. (Pubitemid 20251133)
2. Ajayi OB, &, Ukwade MT, (2001): Caffeine and intraocular pressure in a Nigerian population. J Glaucoma 10: 25-31. (Pubitemid 32151791)
3. Altman DG, (1991): Practical statistics for medical research, 1st edn. London: Chapman & Hall/CRC 170-171.
4. Avisar R, Avisar E, &, Weinberger D, (2002): Effect of coffee consumption on intraocular pressure. Ann Pharmacothe 36: 992-995. (Pubitemid 34564381)
5. Blum M, Bachmann K, Winzer D, et al., (1999): Noninvasive measurement of the Bayliss effect in retinal autoregulation. Graefes Arch Clin Exp Ophthalmol 237: 296-300. (Pubitemid 29145807)
6. Blum M, Kubetschka U, Hunger-Dathe W, et al., (2000): Autoregulation of retinal arterioles in diabetics and normal subjects. Klin Monatsbl Augenheilkd 216: 40-44. German (Pubitemid 30123343)
7. Bottcher M, Czernin J, Sun KT, et al., (1995): Effect of caffeine on mycardial blood flow at rest and during pharmacological vasodilation. J Nucl Med 36: 2016-2021.
8. Campochiaro PA, &, Sen HN, (1989): Adenosine and agonists cause vasodilation and hemorrhages.Implications for ischemic retinopathies. Arch Ophthalmol 107: 412-416. (Pubitemid 19078288)
9. Chandrasekaran S, Rochtchina E, &, Mitchell P, (2005): Effects of caffeine on intraocular pressure: the Blue Mountains Eye Study. J Glaucoma 14: 504-507. (Pubitemid 41682247)
10. Garhöfer G, Zawinka C, Resch H, Kothy P, Schmetterer L, &, Dorner GT, (2004): Reduced response of retinal vessel diameters to flicker stimulation in patients with diabetes. Br J Ophthalmol 88: 887-891.
11. Garhöfer G, Bek T, &, Böhm AG, et al., (2010): Use of the retinal vessel analyzer in ocular blood flow research. Acta Ophthalmol 88: 717-722.
12. Gilliland K, &, Andress D, (1981): Ad lib caffeine consumption, symptoms of caffeinism, and academic performance. Am J Psychol 138: 512.
13. Gould L, Venkataram K, Goswami M, et al., (1973): The cardiac effects of coffee. Angiology 24: 455-463.
14. Grunwald JE, Sinclair SH, &, Riva CE, (1982): Autoregulation of the retinal circulation in response to decrease of intraocular pressure below normal. Invest Ophthalmol Vis Sci 23: 124-127. (Pubitemid 12089691)
15. Higginbotham EJ, Kilimanjaro HA, Wilensky JT, et al., (1989): The effect of caffeine on IOP in glaucoma patients. Ophthalmology 5: 624.
16. Lasta M, Polak K, Luksch A, Garhofer G, &, Schmetterer L, (2012): Effect of synthase inhibition of retinal vessel reaction to isometric exercise in healthy humans. Acta Ophthalmol 90: 362-368.
17. Li JKJ, (2004): Dynamics of the vascular system, 1st edn. Singapore: World Scientific.
18. Li M, Wang M, Guo W, et al., (2011): The effect of caffeine on intraocular pressure: a systematic review and meta-analysis. Graefes Arch Clin Exp Ophthalmol 249: 435-442.
19. Lotfi K, &, Grunwald JE, (1991): The effect of caffeine on the human macular circulation. Invest Ophthalmol Vis Sci 32: 3028-3032.
20. Luksch A, Lasta M, Polak K, Fuchsjäger-Mayrl G, Polska E, Garhöfer G, &, Schmetterer L, (2009): Twelve-hr reproducibility of retinal and optic nerve blood flow parameters in healthy individuals. Acta Ophthalmol 87: 875-880.
21. Lunt MJ, Ragab S, Birch AA, et al., (2004): Comparison of caffeine-induced changes in cerebral blood flow and middle cerebral artery blood velocity shows that caffeine reduces middle cerebral artery diameter. Phyiol Meas 25: 467-474. (Pubitemid 38568933)
22. Mathew RJ, &, Wilson WH, (1985): Caffeine-induced changes in cerebral circulation. Stroke 16: 814-817.
23. Nagel E, Vilser W, Fink A, et al., (2006): Variance of retinal vessel diameter response to flicker light. A methodological clinical study. Ophthalmologe 103: 114-119.
24. Okuno T, Sugiyama T, Tominaga M, et al., (2002): Effects of caffeine on microcirculation of the human ocular fundus. Jpn J Ophthalmol 46: 170-176. (Pubitemid 34309031)
25. Ozkan B, Yuksel N, Anik Y, et al., (2008): The effect of caffeine on retrobulbar hemodynamics. Curr Eye Res 33: 804-809.
26. Polak K, Dorner G, Kiss B, Polska E, Findl O, Rainer G, Eichler HG, &, Schmetterer L, (2000): Evaluation of the Zeiss retinal vessel analyser. Br J Ophthalmol 84: 1285-1290.
27. Rhodin JA, (1968): Ultrastructure of mammalian venous capillaries, venules, and collecting veins. J Ultrastruct Res 25: 452-500.
28. Schmetterer L, &, Garhofer G, (2007): How can blood flow be measured? Surv Ophthalmol 52 (Suppl. 2): S134-S138. (Pubitemid 350060964)
29. Seifert BU, &, Vilser W, (2002): Retinal vessel analyzer (RVA)-design and function. Biomed Tech (Berl) 47 (Suppl 1): Pt 2 678-681.
30. Smits P, Thien TH, &, Van'tlaar A, (1985): The cardiovascular effects of regular and decaffeinated coffee. Br J Pharmacol 19: 852.
31. Whitsett TL, Manion CV, &, Christensen HD, (1984): Cardiovascular effects of coffee and caffeine. Am J Cardiol 53: 918.