The association between insight and symptoms in bipolar inpatients: An Italian prospective study

European Psychiatry

Volumn 27, Issue 8, 2012, Pages 619-624

  Bressi, C ^a   Porcellana, M ^b   Marinaccio, P M ^a   Nocito, E P ^a   Ciabatti, M ^a   Magri, L ^a   Altamura, A C ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b OSPEDALE NIGUARDA CA GRANDA   (Italy)

Author keywords

Bipolar disorder; Insight; Quality of life

Indexed keywords

ARIPIPRAZOLE; LITHIUM; MOOD STABILIZER; NEUROLEPTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE; VALPROIC ACID;

ADULT; ARTICLE; BIPOLAR DEPRESSION; BIPOLAR DISORDER; BIPOLAR MANIA; FEMALE; HAMILTON SCALE; HUMAN; INTROSPECTION; ITALY; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MENTAL PATIENT; MIXED MANIA AND DEPRESSION; PRIORITY JOURNAL; RATING SCALE; SCALE TO ASSESS UNAWARENESS OF MENTAL DISORDER; YOUNG MANIA RATING SCALE;

ADULT; AWARENESS; BIPOLAR DISORDER; FEMALE; HUMANS; INPATIENTS; ITALY; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; PSYCHIATRIC STATUS RATING SCALES; REGRESSION ANALYSIS; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 84868212640     PISSN: 09249338     EISSN: 17783585     Source Type: Journal    
DOI: 10.1016/j.eurpsy.2011.09.002     Document Type: Article

References (53)

1. Altamura A.C., Bassetti R., Sassella F., Salvadori D., Mundo E. Duration of untreated psychosis as a predictor of outcome in first-episode schizophrenia: a retrospective study. Schizophr Res 2001, 52:29-36.
2. Altamura A.C., Bassetti R., Bigotti S., Pioli R., Mundo E. Clinical variables related to suicide attempts in schizophrenic patients: a retrospective study. Schizophr Res 2003, 60:47-55.
3. Altamura A.C., Dell'Osso B., Vismara S., Mundo E. May duration of untreated illness influence the long-term course of major depressive disorder?. Eur Psychiatr 2008, 23:92-96.
4. Altamura A.C., Buoli M., Albano A., Dell'Osso B. Age at onset and latency to treatment (duration of untreated illness) in patients with mood and anxiety disorders: a naturalistic study. Int Clin Psychopharmacol 2010, 25:172-179.
5. Altamura A.C., Dell'Osso B., Berlin H.A., Buoli M., Bassetti R., Mundo E. Duration of untreated illness and suicide in bipolar disorder: a naturalistic study. Eur Arch Psychiatry Clin Neurosci 2010, 260:385-391.
6. Altamura A.C., Porcellana M., Marinaccio P.M., Ciabatti M., Nocito E.P., Magri L., et al. Is it possible to assess subjective well-being among bipolar inpatients? An 18-week follow-up study. Gen Hosp Psychiatry 2011, 33:185-190.
7. Amador X.F., Strauss D.H., Yale S., Gorman J.M., Endicott J. The assessment of insight in psychosis. Am J Psychiatry 1993, 150:873-879.
8. Amador X.F., Flaum M., Andreasen N.C., Strauss D.H., Yale S.A., Clark S.C., et al. Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch Gen Psychiatry 1994, 51:826-836.
9. Amador X.F., Friedman J.H., Kasapis C., Yale S.A., Flaum M., Gorman J.M. Suicidal behavior in schizophrenia and its relationship to awareness of illness. Am J Psychiatry 1996, 153:1185-1188.
10. Amador X.F., David A.S. Insight and psychosis 2004, Oxford University Press, New York. 2nd ed.
11. Angst J., Sellaro R. Historical perspectives and natural history of bipolar disorder. Biol Psychiatry 2000, 48:445-457.
12. Bauer M., Unutzer J., Pincus H.A., Lawson W.B. Bipolar disorder. Ment Health Serv Res 2002, 4:225-229.
13. Buckley P.F., Hrouda D.R., Friedman L., Noffsinger S.G., Resnick P.J., Camlin-Shingler K. Insight and its relationship to violent behavior in patients with schizophrenia. Am J Psychiatry 2004, 161:1712-1714.
14. Cassidy F. Insight in bipolar disorder: relationship to episode subtypes and symptom dimensions. Neuropsychiatr Dis Treat 2010, 6:627-631.
15. Cuffel B.J., Alford J., Fisher E.P., Owen R.R. Awareness of illness in schizophrenia and outpatient treatment adherence. J Nerv Ment Dis 1996, 184:653-659.
16. De Hert M.A.F., Simon V., Vidovic D., Franic T., Wampers M., Peuskens J., et al. Evaluation of the association between insight and symptoms in a large sample of patients with schizophrenia. Eur Psychiatry 2009, 24:507-512.
17. Dell'Osso L., Pini S., Cassano G.B., Mastrocinque C., Seckinger R.A., Saettoni M., et al. Insight into illness in patients with mania, mixed mania, bipolar depression and major depression with psychotic features. Bipolar Disord 2002, 4:315-322.
18. Dias V.V., Brissos S., Carita A.I. Clinical and neurocognitive correlates of insight in patients with bipolar I disorder in remission. Acta Psychiatr Scand 2008, 117:28-34.
19. Dias V.V., Brissos S., Frey B.N., Kapczinski F. Insight, quality of life and cognitive functioning in euthymic patients with bipolar disorder. J Affect Dis 2008, 110:75-83.
20. First M.B., Gibbon M., Spitzer R.L., Williams J.B. User Guide for the Structural Clinical Interview for DSM-IV (SCID) Axis I Disorders 1996, American Psychiatry Association, Washington, DC.
21. Ghaemi S.N., Boiman E., Goodwin F.K. Insight and outcome in bipolar, unipolar and anxiety disorders. Compr Psychiatry 2000, 41:167-171.
22. Ghaemi S.N., Rosenquist K.J. Is insight in mania state-dependent? A meta-analysis. J Nerv Ment Dis 2004, 192:771-775.
23. Gharabawi G.M., Lasser R.A., Bossie C.A., Zhu Y., Amador X. Insight and its relationship to clinical outcomes in patients with schizophrenia or schizoaffective disorder receiving long-acting risperidone. Int Clin Psychopharmacol 2006, 21:233-240.
24. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960, 23:56-62.
25. Kaiser S.L., Snyder J.A., Corcoram R., Drake R.J. The relationship among insight, social support and depression in psychosis. J Nerv Ment Dis 2006, 194:905-908.
26. Kemp R.A., Lambert T.J. Insight in schizophrenia and its relationship to psychopathology. Schizophr Res 1995, 18:21-28.
27. Kessing L.V., Sondergard L., Kvist K., Andersen P.K. Suicide risk in patient treated with lithium. Arch Gen Psychiatry 2005, 62:860-866.
28. MacQueen G.M., Young L.T., Joffe R.T. A review of psychosocial outcome in patients with bipolar disorder. Acta Psychiatr Scand 2001, 103:163-170.
29. Mintz A.R., Dobson K.S., Rommey D.M. Insight in schizophrenia: a meta-analysis. Schizophr Res 2003, 61:75-88.
30. Moore O., Cassidy E., Carr A., O'Callaghan E. Unawareness of illness and its relationship with depression and self-deception in schizophrenia. Eur Psychiatry 1999, 14:264-269.
31. Osatuke K., Ciesla J., Kaskow J.W., Zisook S., Mohamed S. Insight in schizophrenia: a review of etiological models and supporting research. Compr Psychiatry 2008, 49:70-77.
32. Pallanti S., Quercioli L., Pazzagli A., Rossi A., Dell'Osso L., Pini S., et al. Awareness of illness and subjective experience of cognitive complaints in patients with bipolar I and bipolar II disorder. Am J Psychiatry 1999, 156:1094-1096.
33. Peralta V., Cuesta M.J. Lack of insight in mood disorder. J Affect Dis 1998, 49:55-58.
34. Pini S., de Queiroz V., Dell'Osso L., Abelli M., Mastrocinque C., Saettoni M., et al. Cross-sectional similarities and differences between schizophrenia, schizoaffective disorder and mania or mixed mania with mood-incongruent psychotic features. Eur Psychiatry 2004, 19:8-14.
35. Pyne J.M., Bean D., Sullivan G. Characteristics of patients who do not believe they are mentally ill. J Nerv Ment Dis 2001, 189:146-153.
36. Rossi A., Daneluzzo E., Arduini L., Di Domenico M., Stratta P., Petruzzi C. Cognitive symptoms of mania in pure and mixed episodes evaluated with the positive and negative syndrome scale. Eur Arch Psychiatry Clin Neurosci 2000, 250:254-256.
37. Schwartz R.C., Smith S.D. Suicidality and psychosis: the predictive potential of symptomatology and insight into illness. J Psychiatr Res 2004, 38:185-191.
38. Scott J. Psychotherapy for bipolar disorder. Br J Psychiatry 1995, 167:581-588.
39. Sevy S., Nathanson K., Visweswaraiah H., Amador X. The relationship between insight and symptoms in schizophrenia. Compr Psychiatry 2004, 45:16-19.
40. Shad M.U., Muddasani S., Keshevan M.S. Prefrontal subregions and dimensions of insight in first-episode schizophrenia: a pilot study. Psychiatry Res 2006, 146:35-42.
41. Smith T.E., Hull J.W., Goodman M., Hedayat-Harris A., Willson D.F., Israel L.M., et al. The relative influence of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder. J Nerv Ment Dis 1999, 187:102-108.
42. Spearing M.K., Post R.M., Leverich G.S., Brandt D., Nolein W. Modification of the Clinical Global Impressions (CGI) scale for use in bipolar illness (BP): the CGI-BP. Psychiatry Res 1997, 73:159-171.
43. van der Werf-Eldering M.J., van der Meer L., Burger H., Holthausen E.A.E., Nolen W.A., Aleman A. Insight in bipolar disorder: associations with cognitive and emotional processing and illness characteristics. Bipolar Disord 2011, 13:343-354.
44. Varga M., Magnusson A., Flekkoy K., Ronneberg U., Opjordsmoen S. Insight, symptoms and neurocognition in bipolar I patients. J Affect Disord 2006, 91:1-9.
45. Varga M., Magnusson A., Flekkoy K., David A.S., Opjordsmoen S. Clinical and nueropsychological correlates of insight in schizophrenia and bipolar I disorder: does diagnosis matter?. Compr Psychiatry 2007, 48:583-591.
46. Weiler M.A., Fleisher M.H., McArthur-Campbell D. Insight and symptom change in schizophrenia and other disorders. Schizophr Res 2000, 45:29-36.
47. Wiffen B.D.R., Rabinowitz J., Lex A., David A.S. Correlates, change and 'state or trait' properties of insight in schizophrenia. Schizophr Res 2010, 122:94-103.
48. Yen C.F., Chen C.S., Yeh M.L., Ker J.H., Yang S.J., Yen J.Y. Correlates of insight among patients with bipolar I disorder in remission. J Affect Disord 2004, 78:57-60.
49. Yen C.F., Chen C.S., Ko C.H., Yeh M.L., Yang S.J., Yen J.Y., et al. Relationship between insight and medication adherence in outpatients with schizophrenia and bipolar disorder: prospective study. Psychiatry Clin Neurosci 2005, 59:403-409.
50. Yen C.F., Chen C.S., Ko C.H., Yen J.Y., Huang C.F. Changes in insight among patients with bipolar I disorder: a 2-year prospective study. Bipolar Disord 2007, 9:238-242.
51. Yen C.F., Chen C.S., Yen J.Y., Ko C.H. The predictive effect of insight on adverse clinical outcomes in bipolar I disorder: a 2-year prospective study. J Affect Disord 2008, 108:121-127.
52. Yen C.F., Cheng C.P., Huang C.F., Ko C.H., Yen J.Y., Chang Y.P., et al. Relationship between psychosocial adjustment and executive function in patients with bipolar disorder and schizophrenia in remission: the mediating and moderating effects of insight. Bipolar Disord 2009, 11:190-197.
53. Young R., Biggs J., Meyer D.A. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978, 133:429-435.