Does the surface-treated AN69 membrane prolong filter survival in CRRT without anticoagulation?

Intensive Care Medicine

Volumn 38, Issue 11, 2012, Pages 1818-1825

  Schetz, Miet ^a   Van Cromphaut, Sophie ^a   Dubois, Jasperina ^a   Van Den Berghe, Greet ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

AN69ST membrane; Continuous renal replacement therapy; Filter survival; Heparin coated; Thrombogenicity

Indexed keywords

AN69 MEMBRANE; AN69ST MEMBRANE; ANTICOAGULATION; ARTICLE; BLEEDING; CLINICAL ARTICLE; CONTINUOUS RENAL REPLACEMENT THERAPY; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; FEMALE; FILTER; HEMOFILTRATION; HUMAN; INTERMETHOD COMPARISON; MALE; RANDOMIZED CONTROLLED TRIAL; SURVIVAL; THROMBOGENICITY;

ACRYLIC RESINS; COATED MATERIALS, BIOCOMPATIBLE; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; EQUIPMENT DESIGN; FEMALE; FIBRINOLYTIC AGENTS; HEMOFILTRATION; HEPARIN; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MEMBRANES, ARTIFICIAL; MIDDLE AGED; POLYETHYLENEIMINE; PROSPECTIVE STUDIES;

EID: 84868210557     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2633-x     Document Type: Article

References (26)

1. Oudemans-van Straaten HM, Wester JP, de Pont AC, Schetz MR (2006) Anticoagulation strategies in continuous renal replacement therapy: can the choice be evidence based? Intensive Care Med 32:188-202
2. Oudemans-van Straaten HM (2010) Citrate anticoagulation for continuous renal replacement therapy in the critically ill. Blood Purif 29:191-196
3. Thomas M, Valette P, Mausset AL, Déjardin P (2000) High molecular weight kininogen adsorption on hemodialysis membranes: influence of pH and relationship with contact phase activation of blood plasma. influence of pre-treatment with poly(ethyleneimine). Int J Artif Organs 23:20-26
4. Chanard J, Lavaud S, Paris B, Toure F, Rieu P, Renaux JL, Thomas M (2005) Assessment of heparin binding to the AN69 ST hemodialysis membrane: I Preclinical studies. ASAIO J 51:342-347
5. Lavaud S, Paris B, Maheut H, Randoux C, Renaux JL, Rieu P, Canard J (2005) Assessment of the heparin-binding AN69 ST hemodialysis membrane: II. Clinical studies without heparin administration. ASAIO J 51:348-351
6. Evenepoel P, Dejagere T, Verhamme P, Claes K, Kuypers D, Bammens B, Vanrenterghem Y (2007) Heparincoated polyacrylonitrile membrane versus regional citrate anticoagulation: a prospective randomized study of 2 anticoagulation strategies in patients at risk of bleeding. Am J Kidney Dis 49:642-649
7. Richtrova P, Rulcova K, Mares J, Reischig T (2010) Evaluation of three different methods to prevent dialyzer clotting without causing systemic anticoagulation effect. Artif Organs 35:83-88
8. Sagedal S, Witczak BJ, Osnes K, Hartmann A, Os I, Eikvar L, Klingenberg O, Brosstad F (2011) A heparin-coated dialysis filter (AN69 ST) does not reduce clotting during hemodialysis when compared to a conventional polysulfone filter (F × 8). Blood Purif 32:151-155
9. Brunet Ph, Frances J, Vacher-Coponat H, Jaubert D, Lebrun G, Gondouin B, Duval A, Berland Y (2011) Hemodialysis without heparin: a randomized, controlled, crossover study of two dialysis membranes (AN69ST and polysulfone F60). Int J Artif Organs 34:1165-1171
10. Burry LD, Tung DD, Hallett D, Bailie T, Carvalhana V, Lee D, Ramganesh S, Richardson R, Mehta S, Lapinsky SE (2009) Regional Citrate Anticoagulation for PrismaFlex Continuous Renal Replacement Therapy. Annals Pharmacother 43:1419-1425 (abstract)
11. Xie W, Heidenreich S, Abbas S, Mann H (2009) Alteration of membrane properties in hemofilters during continuous hemofiltration (CVVH). ASAIO J 55:178 (abstract)
12. Xie WH, Heidenreich S, Vienken J, Mann H (2010) Shear stress in the hollow fibers and protein permeability during continuous hemofiltration. Int J Artif Organs 33:443 (abstract)
13. Kleger GR, Fässler E (2010) Can circuit lifetime be a quality indicator in continuous renal replacement therapy in the critically ill? Int J Artif Organs 33:139-146
14. Lavaud S, Canivet E, Wuillai A, Maheut H, Randoux C, Bonnet JM, Renaux JL, Chanard J (2003) Optimal anticoagulation strategy in haemodialysis with heparin-coated polyacrylonitrile membrane. Nephrol Dial Transpl 18:2097-2104
15. Chanard J, Lavaud S, Maheut H, Kazes I, Vitry F, Rieu P (2008) The clinical evaluation of low-dose heparin in haemodialysis: a prospective study using the heparin-coated AN69 ST membrane. Nephrol Dial Transpl 23:2003-2009
16. Kappelmayer J, Bernabei A, Edmunds LH Jr, Edgington TS, Colman RW (1993) Tissue factor is expressed on monocytes during simulated extracorporeal circulation. Circ Res 72:1075-1081
17. Tabuchi N, Shibamiya A, Koyama T, Fukuda T, Oeveren Wv W, Sunamori M (2003) Activated leukocytes adsorbed on the surface of an extracorporeal circuit. Artif Organs 27:591-594
18. Keuren JF, Wielders SJ, Willems GM, Morra M, Lindhout T (2002) Fibrinogen adsorption, platelet adhesion and thrombin generation at heparinized surfaces exposed to flowing blood. Thromb Haemost 87:742-747
19. Zemanova P, Opatmy K, Vit L, Sefma F (2005) Tissue factor, its inhibitor, and the thrombogenicity of two new synthetic membranes. Artif Organs 29:651-657
20. Barstad RM, Hamers MJ, Møller AS, Sakariassen KS (1998) Monocyte procoagulant activity induced by adherence to an artificial surface is reduced by end-point immobilized heparin-coating of the surface. Thromb Haemost 79:302-305
21. Semeraro F, Ammollo CT, Semeraro N, Colucci M (2009) Tissue factorexpressing monocytes inhibit fibrinolysis through a TAFI-mediated mechanism, and make clots resistant to heparins. Haematologica 94:819-826
22. Levi M, van der Poll T, ten Cate H (2006) Tissue factor in infection and severe inflammation. Semin Thromb Hemost 32:33-39
23. Osterud B (1998) Tissue factor expression by monocytes: regulation and pathophysiological roles. Blood Coagul Fibrinolysis 9(Suppl 1):S9-S14
24. Joannidis M, Oudemans-van Straaten HM (2007) Clinical review: patency of the circuit in continuous renal replacement therapy. Crit Care 11:218
25. Young E, Prins M, Levine MN, Hirsh J (1992) Heparin binding to plasma proteins, an important mechanism for heparin resistance. Thromb Haemost 67:639-643
26. Young E, Podor TJ, Venner T, Hirsh J (1997) Induction of the acute-phase reaction increases heparin-binding proteins in plasma. Arterioscler Thromb Vasc Biol 17:1568-1574