Pharmacokinetic interaction between the hepatitis C virus protease inhibitor boceprevir and cyclosporine and tacrolimus in healthy volunteers

Hepatology

Volumn 56, Issue 5, 2012, Pages 1622-1630

  Hulskotte, Ellen ^a   Gupta, Samir ^b   Xuan, Fengjuan ^b   van Zutven, Marga ^a   O'Mara, Edward ^b   Feng, Hwa Ping ^b   Wagner, John ^b   Butterton, Joan ^b  

^a NV ORGANON   (Netherlands)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOCEPREVIR; CYCLOSPORIN; TACROLIMUS;

ABDOMINAL DISCOMFORT; ABDOMINAL DISTENSION; ADULT; AREA UNDER THE CURVE; ARTICLE; ASTHENIA; CHILL; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG SAFETY; DRUG TOLERABILITY; DYSGEUSIA; FATIGUE; FEMALE; FLATULENCE; FLUSHING; GASTROESOPHAGEAL REFLUX; HEADACHE; HEART PALPITATION; HUMAN; MALE; MAXIMUM PLASMA CONCENTRATION; PRIORITY JOURNAL; SIDE EFFECT;

ADULT; ANTIVIRAL AGENTS; AREA UNDER CURVE; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FEMALE; HEPATITIS C; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; PROLINE; PROTEASE INHIBITORS; TACROLIMUS; YOUNG ADULT;

EID: 84868208266     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.25831     Document Type: Article

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