Short-and long-term outcomes of coronary stenting in women versus men: Results from the national cardiovascular data registry centers for medicare & medicaid services cohort

Circulation

Volumn 126, Issue 18, 2012, Pages 2190-2199

  Anderson, Monique L ^a   Peterson, Eric D ^a   Matthew Brennan, J ^a   Rao, Sunil V ^a   Dai, David ^a   Anstrom, Kevin J ^a   Piana, Robert ^b   Popescu, Andra ^c   Sedrakyan, Art ^d   Messenger, John C ^e   Douglas, Pamela S ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c CHRISTIANA CARE HEALTH SYSTEM   (United States)

^d WEILL CORNELL MEDICAL COLLEGE   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

bare metal stents; coronary disease; drug eluting stents; proportional hazards models; sex factors

Indexed keywords

AGED; ARTICLE; BARE METAL STENT; BLEEDING; CORONARY STENT; DEATH; DRUG ELUTING STENT; FEMALE; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REVASCULARIZATION; RISK ASSESSMENT; SEX DIFFERENCE; TREATMENT OUTCOME; VASCULAR DISEASE;

AGED; AGED, 80 AND OVER; ANGIOPLASTY, BALLOON, CORONARY; ANTICOAGULANTS; CARDIOVASCULAR AGENTS; COMBINED MODALITY THERAPY; CORONARY ARTERY BYPASS; CORONARY DISEASE; DRUG-ELUTING STENTS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INPATIENTS; KAPLAN-MEIER ESTIMATE; MALE; MEDICAID; MEDICARE; ODDS RATIO; POSTOPERATIVE COMPLICATIONS; PROPORTIONAL HAZARDS MODELS; REGISTRIES; RISK; SEX FACTORS; STENTS; TREATMENT OUTCOME; UNITED STATES;

EID: 84868208094     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.111369     Document Type: Article

References (44)

1. Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D, Turner MB; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2012;125:188-197.
2. Argulian E, Patel AD, Abramson JL, Kulkarni A, Champney K, Palmer S, Weintraub W, Wenger NK, Vaccarino V. Gender differences in short-term cardiovascular outcomes after percutaneous coronary interventions. Am J Cardiol. 2006;98:48-53.
3. Chauhan MS, Ho KK, Baim DS, Kuntz RE, Cutlip DE. Effect of gender on in-hospital and one-year outcomes after contemporary coronary artery stenting. Am J Cardiol. 2005;95:101-104.
4. Peterson ED, Lansky AJ, Kramer J, Anstrom K, Lanzilotta MJ; National Cardiovascular Network Clinical Investigators. Effect of gender on the outcomes of contemporary percutaneous coronary intervention. Am J Cardiol. 2001;88:359-364.
5. Jacobs AK, Johnston JM, Haviland A, Brooks MM, Kelsey SF, Holmes DR Jr, Faxon DP, Williams DO, Detre KM. Improved outcomes for women undergoing contemporary percutaneous coronary intervention: a report from the National Heart, Lung, and Blood Institute Dynamic Registry. J Am Coll Cardiol. 2002;39:1608-1614.
6. Stone GW, Ellis SG, Cox DA, Hermiller J, O'Shaughnessy C, Mann JT, Turco M, Caputo R, Bergin P, Greenberg J, Popma JJ, Russell ME; TAXUS-IV Investigators. A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med. 2004;350:221-231.
7. Stone GW, Ellis SG, Cannon L, Mann JT, Greenberg JD, Spriggs D, O'Shaughnessy CD, DeMaio S, Hall P, Popma JJ, Koglin J, Russell ME; TAXUS V Investigators. Comparison of a polymer-based paclitaxeleluting stent with a bare metal stent in patients with complex coronary artery disease: a randomized controlled trial. JAMA. 2005;294: 1215-1223.
8. Stone GW, Moses JW, Ellis SG, Schofer J, Dawkins KD, Morice MC, Colombo A, Schampaert E, Grube E, Kirtane AJ, Cutlip DE, Fahy M, Pocock SJ, Mehran R, Leon MB. Safety and efficacy of sirolimus-and paclitaxel-eluting coronary stents. N Engl J Med. 2007;356:998-1008.
9. Stone GW, Lansky AJ, Pocock SJ, Gersh BJ, Dangas G, Wong SC, Witzenbichler B, Guagliumi G, Peruga JZ, Brodie BR, Dudek D, Möckel M, Ochala A, Kellock A, Parise H, Mehran R; HORIZONS-AMI Trial Investigators. Paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction. N Engl J Med. 2009;360:1946-1959.
10. Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O'Shaughnessy C, Caputo RP, Kereiakes DJ, Williams DO, Teirstein PS, Jaeger JL, Kuntz RE; SIRIUS Investigators. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349:1315-1323.
11. Morice MC, Serruys PW, Sousa JE, Fajadet J, Ban Hayashi E, Perin M, Colombo A, Schuler G, Barragan P, Guagliumi G, Molnàr F, Falotico R; RAVEL Study Group. Randomized study with the sirolimus-coated Bx Velocity balloon-expandable stent in the treatment of patients with de novo native coronary artery lesions: a randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med. 2002;346:1773-1780.
12. Mikhail GW, Gerber RT, Cox DA, Ellis SG, Lasala JM, Ormiston JA, Stone GW, Turco MA, Joshi AA, Baim DS, Colombo A. Influence of sex on long-term outcomes after percutaneous coronary intervention with the paclitaxel-eluting coronary stent: results of the "TAXUS Woman" analysis. JACC Cardiovasc Interv. 2010;3:1250-1259.
13. Onuma Y, Kukreja N, Daemen J, Garcia-Garcia HM, Gonzalo N, Cheng JM, van Twisk PH, van Domburg R, Serruys PW; Interventional Cardiologists of Thoraxcenter. Impact of sex on 3-year outcome after percutaneous coronary intervention using bare-metal and drug-eluting stents in previously untreated coronary artery disease: insights from the RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated at Rotterdam Cardiology Hospital) Registries. JACC Cardiovasc Interv. 2009;2: 603-610.
14. Draft guidance for industry and Food and Drug Administration staff: evaluation of sex differences in medical device clinical studies. Food and Drug Administration Web site. http://www.fda.gov/MedicalDevices/ DeviceRegulationandGuidance/GuidanceDocuments/ucm283453.htm. Updated December 19, 2011. Accessed April 6, 2012.
15. Brindis RG, Fitzgerald S, Anderson HV, Shaw RE, Weintraub WS, Williams JF. The American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR): building a national clinical data repository. J Am Coll Cardiol. 2001;37:2240-2245.
16. Douglas PS, Brennan JM, Anstrom KJ, Sedrakyan A, Eisenstein EL, Haque G, Dai D, Kong DF, Hammill B, Curtis L, Matchar D, Brindis R, Peterson ED. Clinical effectiveness of coronary stents in elderly persons: results from 262,700 Medicare patients in the American College of Cardiology-National Cardiovascular Data Registry. J Am Coll Cardiol. 2009;53:1629-1641.
17. Cannon CP, Battler A, Brindis RG, Cox JL, Ellis SG, Every NR, Flaherty JT, Harrington RA, Krumholz HM, Simoons ML, Van De Werf FJ, Weintraub WS, Mitchell KR, Morrisson SL, Brindis RG, Anderson HV, Cannom DS, Chitwood WR, Cigarroa JE, Collins-Nakai RL, Ellis SG, Gibbons RJ, Grover FL, Heidenreich PA, Khandheria BK, Knoebel SB, Krumholz HL, Malenka DJ, Mark DB, Mckay CR, Passamani ER, Radford MJ, Riner RN, Schwartz JB, Shaw RE, Shemin RJ, Van Fossen DB, Verrier ED, Watkins MW, Phoubandith DR, Furnelli T. American College of Cardiology key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes: a report of the American College of Cardiology Task Force on Clinical Data Standards (Acute Coronary Syndromes Writing Committee). J Am Coll Cardiol. 2001;38:2114-2130.
18. Wang TY, Peterson ED, Dai D, Anderson HV, Rao SV, Brindis RG, Roe MT; National Cardiovascular Data Registry. Patterns of cardiac marker surveillance after elective percutaneous coronary intervention and implications for the use of periprocedural myocardial infarction as a quality metric: a report from the National Cardiovascular Data Registry (NCDR). J Am Coll Cardiol. 2008;51:2068-2074.
19. Bang H, Tsiatis AA. Estimating medical costs with censored data. Biometrika. 2000;87:329-343.
20. Gray RJ. A class of K-sample tests for comparing the cumulative incidence of a competing risk. Ann Statist. 1988;16:1141-1154.
21. Brennan JM, Peterson ED, Messenger JC, Rumsfeld JS, Weintraub WS, Anstrom KJ, Eisenstein EL, Milford-Beland S, Grau-Sepulveda MV, Booth ME, Dokholyan RS, Douglas PS; Duke Clinical Research Institute DEcIDE Team. Linking the National Cardiovascular Data Registry CathPCI Registry with Medicare claims data: validation of a longitudinal cohort of elderly patients undergoing cardiac catheterization. Circ Cardiovasc Qual Outcomes. 2012;5:134-140.
22. Akhter N, Milford-Beland S, Roe MT, Piana RN, Kao J, Shroff A. Gender differences among patients with acute coronary syndromes undergoing percutaneous coronary intervention in the American College of Cardiology-National Cardiovascular Data Registry (ACC-NCDR). Am Heart J. 2009;157:141-148.
23. Duvernoy CS, Smith DE, Manohar P, Schaefer A, Kline-Rogers E, Share D, McNamara R, Gurm HS, Moscucci M. Gender differences in adverse outcomes after contemporary percutaneous coronary intervention: an analysis from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) percutaneous coronary intervention registry. Am Heart J. 2010;159:677.e1-683.e1.
24. Jiang SL, Ji XP, Zhao YX, Wang XR, Song ZF, Ge ZM, Guo T, Zhang C, Zhang Y. Predictors of in-hospital mortality difference between male and female patients with acute myocardial infarction. Am J Cardiol. 2006;98:1000-1003.
25. Oliveira Cardoso C, Cardoso CR, Rodrigues LH, Staudt C, Miller VM, Duarte AF, Yordi LM. Gender impact on in-hospital outcomes after percutaneous coronary intervention. Int J Cardiol. 2009;133:106-109.
26. Lansky AJ, Pietras C, Costa RA, Tsuchiya Y, Brodie BR, Cox DA, Aymong ED, Stuckey TD, Garcia E, Tcheng JE, Mehran R, Negoita M, Fahy M, Cristea E, Turco M, Leon MB, Grines CL, Stone GW. Gender differences in outcomes after primary angioplasty versus primary stenting with and without abciximab for acute myocardial infarction: results of the Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC) trial. Circulation. 2005;111: 1611-1618.
27. Berger JS, Sanborn TA, Sherman W, Brown DL. Influence of sex on in-hospital outcomes and long-term survival after contemporary percutaneous coronary intervention. Am Heart J. 2006;151:1026-1031.
28. Alfonso F, Hernández R, Bañuelos C, Fernández-Ort? ́z A, Escaned J, Sabaté M, Pérez-Vizcayno MJ, Fernández C, Macaya C. Initial results and long-term clinical and angiographic outcome of coronary stenting in women. Am J Cardiol. 2000;86:1380-1383, A5.
29. Srinivas VS, Garg S, Negassa A, Bang JY, Monrad ES. Persistent sex difference in hospital outcome following percutaneous coronary intervention: results from the New York State reporting system. J Invasive Cardiol. 2007;19:265-268.
30. Thompson CA, Kaplan AV, Friedman BJ, Jayne JE, Gerling BR, Niles NW, Hettleman BD, Robb JF. Gender-based differences of percutaneous coronary intervention in the drug-eluting stent era. Catheter Cardiovasc Interv. 2006;67:25-31.
31. Lansky AJ, Mehran R, Dangas G, Desai K, Costantini-Ortiz C, Cristea E, New G, Negoita M, Stone GW, Leon MB. New-device angioplasty in women: clinical outcome and predictors in a 7,372-patient registry. Epidemiology. 2002;13(suppl 3):S46-S51.
32. Watanabe CT, Maynard C, Ritchie JL. Comparison of short-term outcomes following coronary artery stenting in men versus women. Am J Cardiol. 2001;88:848-852.
33. Ahmed JM, Dangas G, Lansky AJ, Mehran R, Hong MK, Mintz GS, Pichard AD, Satler LF, Kent KM, Stone GW, Leon MB. Influence of gender on early and one-year clinical outcomes after saphenous vein graft stenting. Am J Cardiol. 2001;87:401-405.
34. Lansky AJ, Hochman JS, Ward PA, Mintz GS, Fabunmi R, Berger PB, New G, Grines CL, Pietras CG, Kern MJ, Ferrell M, Leon MB, Mehran R, White C, Mieres JH, Moses JW, Stone GW, Jacobs AK; American College of Cardiology Foundation; American Heart Association. Percutaneous coronary intervention and adjunctive pharmacotherapy in women: a statement for healthcare professionals from the American Heart Association. Circulation. 2005;111:940-953.
35. Alexander KP, Chen AY, Roe MT, Newby LK, Gibson CM, Allen-LaPointe NM, Pollack C, Gibler WB, Ohman EM, Peterson ED; CRUSADE Investigators. Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes. JAMA. 2005;294:3108-3116.
36. Mehilli J, Kastrati A, Dirschinger J, Bollwein H, Neumann FJ, Schömig A. Differences in prognostic factors and outcomes between women and men undergoing coronary artery stenting. JAMA. 2000;284:1799-1805.
37. Cantor WJ, Miller JM, Hellkamp AS, Kramer JM, Peterson ED, Hasselblad V, Zidar JP, Newby LK, Ohman EM. Role of target vessel size and body surface area on outcomes after percutaneous coronary interventions in women. Am Heart J. 2002;144:297-302.
38. Arnold AM, Mick MJ, Piedmonte MR, Simpfendorfer C. Gender differences for coronary angioplasty. Am J Cardiol. 1994;74:18-21.
39. Stefanini GG, Kalesan B, Pilgrim T, Räber L, Onuma Y, Silber S, Serruys PW, Meier B, Jüni P, Windecker S. Impact of sex on clinical and angiographic outcomes among patients undergoing revascularization with drug-eluting stents. JACC Cardiovasc Interv. 2012;5:301-310.
40. Grines CL, Schreiber T. Sex differences in the drug-eluting stent era: do they still exist? JACC Cardiovasc Interv. 2012;5:311-312.
41. Tu JV, Bowen J, Chiu M, Ko DT, Austin PC, He Y, Hopkins R, Tarride JE, Blackhouse G, Lazzam C, Cohen EA, Goeree R. Effectiveness and safety of drug-eluting stents in Ontario. N Engl J Med. 2007;357: 1393-1402.
42. Shishehbor MH, Goel SS, Kapadia SR, Bhatt DL, Kelly P, Raymond RE, Galla JM, Brener SJ, Whitlow PL, Ellis SG. Long-term impact of drugeluting stents versus bare-metal stents on all-cause mortality. J Am Coll Cardiol. 2008;52:1041-1048.
43. Groeneveld PW, Matta MA, Greenhut AP, Yang F. Drug-eluting compared with bare-metal coronary stents among elderly patients. J Am Coll Cardiol. 2008;51:2017-2024.
44. Solinas E, Nikolsky E, Lansky AJ, Kirtane AJ, Morice MC, Popma JJ, Schofer J, Schampaert E, Pucelikova T, Aoki J, Fahy M, Dangas GD, Moses JW, Cutlip DE, Leon MB, Mehran R. Gender-specific outcomes after sirolimus-eluting stent implantation. J Am Coll Cardiol. 2007;50:2111-2116.