Inhibitory effect of the recombinant Phoneutria nigriventer Tx1 toxin on voltage-gated sodium channels

Biochimie

Volumn 94, Issue 12, 2012, Pages 2756-2763

  Silva, Anita O ^a   Peigneur, Steve ^b   Diniz, Marcelo R V ^c   Tytgat, Jan ^b   Beirão, Paulo S L ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c FUNDAÇÃO EZEQUIEL DIAS   (Brazil)

Author keywords

Isoform selectivity; Peptide toxin; Sodium channel; Sodium channel inhibition; Sodium current; Spider toxin

Indexed keywords

PHONEUTRIA NIGRIVENTER TOXIN TX1; SPIDER VENOM; TETRODOTOXIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CHANNELOPATHY; ELECTROPHYSIOLOGY; MALE; NEUROPATHIC PAIN; NONHUMAN; OOCYTE; PHONEUTRIA NIGRIVENTER; PROTEIN EXPRESSION; RAT; SPIDER; SPINAL GANGLION; XENOPUS;

ACTION POTENTIALS; ANIMALS; BINDING, COMPETITIVE; CELLS, CULTURED; CONOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GANGLIA, SPINAL; HUMANS; ION CHANNEL GATING; MALE; MICE; NEURONS; NEUROPEPTIDES; OOCYTES; PROTEIN ISOFORMS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; SODIUM CHANNEL BLOCKERS; SPIDER VENOMS; TETRODOTOXIN; VOLTAGE-GATED SODIUM CHANNELS; XENOPUS LAEVIS;

ARANEAE; ARTHROPODA; PHONEUTRIA NIGRIVENTER;

EID: 84868206491     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2012.08.016     Document Type: Article

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