Large Animal Studies in Pulmonary Hypertension-What Phenotype do We Need to Model?

Journal of Surgical Research

Volumn 178, Issue 1, 2012, Pages 115-118

  Lahm, Tim ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMBIENT AIR; ANIMAL EXPERIMENT; ARTERIAL OXYGEN TENSION; ARTERIAL PRESSURE; ARTERY CATHETERIZATION; ARTERY INTIMA PROLIFERATION; CENTRAL VENOUS PRESSURE; CHEMICAL ANALYSIS; DISEASE MODEL; ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE FAILURE; HEART OUTPUT; HEART RIGHT VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; HEMODYNAMIC PARAMETERS; HUMAN; HYPERVOLEMIA; LUNG CAPILLARY PRESSURE; LUNG VASCULAR RESISTANCE; MEAN ARTERIAL PRESSURE; NONHUMAN; NOTE; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGENATION; PHENOTYPE; PRIORITY JOURNAL; PULMONARY ARTERY; PULMONARY ARTERY OCCLUSION; PULMONARY HYPERTENSION; SHEEP;

ANIMALS; DISEASE MODELS, ANIMAL; EMBOLISM, AIR; FEMALE; HYPERTENSION, PULMONARY; PULMONARY EMBOLISM;

EID: 84868205246     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.06.070     Document Type: Note

References (20)

1. M. Rabinovitch Molecular pathogenesis of pulmonary arterial hypertension J Clin Invest 118 2008 2372
2. N.W. Morrell, S. Adnot, and S.L. Archer Cellular and molecular basis of pulmonary arterial hypertension J Am Coll Cardiol 54 2009 S20
3. M. Humbert, O. Sitbon, and A. Chaouat Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era Circulation 122 2010 156
4. N. Galie, A. Manes, and L. Negro A meta-analysis of randomized controlled trials in pulmonary arterial hypertension Eur Heart J 30 2009 394
5. B. Sztrymf, R. Souza, and L. Bertoletti Prognostic factors of acute heart failure in patients with pulmonary arterial hypertension Eur Respir J 35 2010 1286
6. R.T. Zamanian, F. Haddad, and R.L. Doyle Management strategies for patients with pulmonary hypertension in the intensive care unit Crit Care Med 35 2007 2037
7. A.M. Keogh, E. Mayer, and R.L. Benza Interventional and surgical modalities of treatment in pulmonary hypertension J Am Coll Cardiol 54 2009 S67
8. T. Lahm, C.A. McCaslin, and T.C. Wozniak Medical and surgical treatment of acute right ventricular failure J Am Coll Cardiol 56 2010 1435
9. M.M. Hoeper, J.A. Barbera, and R.N. Channick Diagnosis, assessment, and treatment of non-pulmonary arterial hypertension pulmonary hypertension J Am Coll Cardiol 54 2009 S85
10. M.M. Hoeper, E. Mayer, and G. Simonneau Chronic thromboembolic pulmonary hypertension Circulation 113 2006 2011
11. K.R. Stenmark, B. Meyrick, and N. Galie Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure Am J Physiol Lung Cell Mol Physiol 297 2009 L1013
12. K.R. Stenmark, K.A. Fagan, and M.G. Frid Hypoxia-induced pulmonary vascular remodeling: Cellular and molecular mechanisms Circ Res 99 2006 675
13. I. Shelub, A. van Grondelle, and R. McCullough A model of embolic chronic pulmonary hypertension in the dog J Appl Physiol 56 1984 810
14. E.A. Perkett, K.L. Brigham, and B. Meyrick Continuous air embolization into sheep causes sustained pulmonary hypertension and increased pulmonary vasoreactivity Am J Pathol 132 1988 444
15. J. Weimann, W. Zink, and P.A. Schnabel Selective vasodilation by nitric oxide inhalation during sustained pulmonary hypertension following recurrent microembolism in pigs J Crit Care 14 1999 133
16. X. Zhou, D. Wang, and C.Y. Castro A pulmonary hypertension model induced by continuous pulmonary air embolization J Surg Res 170 2011 e11
17. P.M. Hassoun, L. Mouthon, and J.A. Barbera Inflammation, growth factors, and pulmonary vascular remodeling J Am Coll Cardiol 54 2009 S10
18. S. Rich, and M. Rabinovitch Diagnosis and treatment of secondary (non-category 1) pulmonary hypertension Circulation 118 2008 2190
19. H.A. Ghofrani, M.W. Wilkins, and S. Rich Uncertainties in the diagnosis and treatment of pulmonary arterial hypertension Circulation 118 2008 1195
20. S. Fischer, M.M. Hoeper, and S. Tomaszek Bridge to lung transplantation with the extracorporeal membrane ventilator Novalung in the veno-venous mode: The initial Hannover experience ASAIO J 53 2007 168