Overview and update of the phase III Multicenter Selective Lymphadenectomy Trials (MSLT-I and MSLT-II) in melanoma

Clinical and Experimental Metastasis

Volumn 29, Issue 7, 2012, Pages 699-706

  Morton, Donald L ^a  

^a JOHN WAYNE CANCER INSTITUTE   (United States)

Author keywords

Lymphatic mapping; Melanoma; Micrometastases; Phase III multicenter trial; Sentinel node biopsy

Indexed keywords

BIOPSY; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURGERY; CANCER SURVIVAL; CONFERENCE PAPER; DILUTION; DISEASE FREE SURVIVAL; HOSPITALIZATION; HUMAN; HYPOTHESIS; INTRAOPERATIVE PERIOD; LENGTH OF STAY; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; LYMPHOSCINTIGRAPHY; MELANOMA; MULTICENTER SELECTIVE LYMPHADENECTOMY; QUALITY OF LIFE; SENTINEL NODE BIOPSY; TUMOR BIOPSY;

HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MELANOMA; QUALITY OF LIFE; SENTINEL LYMPH NODE BIOPSY; SKIN NEOPLASMS; SURVIVAL;

EID: 84868205047     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-012-9503-3     Document Type: Conference Paper

References (17)

1. Balch CM, Soong SJ, Gershenwald JE et al (2001) Prognostic factors analysis of 17,600 melanoma patients: Validation of the American Joint Committee on Cancer melanoma staging system. J Clin Oncol 19:3622-3634
2. Morton DL, Hoon DS, Cochran AJ et al. (2003) Lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: Therapeutic utility and implications of nodal microanatomy and molecular staging for improving the accuracy of detection of nodal micrometastases. Ann Surg 238:538-49 (discussion 49-50)
3. Holmes EC, Moseley HS, Morton DL, Clark W, Robinson D, Urist MM (1977) A rational approach to the surgical management of melanoma. Ann Surg 186:481-490
4. Morton DL, Cochran AJ, Thompson JF et al. (2005) Sentinel node biopsy for early-stage melanoma: Accuracy and morbidity in MSLT-I, an international multicenter trial. Ann Surg 242:302-11 (discussion 11-3)
5. Balch CM, Soong S, Ross MI et al (2000) Long-term results of a multi-institutional randomized trial comparing prognostic factors and surgical results for intermediate thickness melanomas (1.0 to 4.0 mm). Intergroup Melanoma Surgical Trial. Ann Surg Oncol 7:87-97
6. Robinson DS, Sample WF, Fee HJ, Holmes C, Morton DL (1977) Regional lymphatic drainage in primary malignant melanoma of the trunk determined by colloidal gold scanning. Surg Forum 28:147-148
7. Wong JH, Cagle LA, Morton DL (1991) Lymphatic drainage of skin to a sentinel lymph node in a feline model. Ann Surg 214:637-641
8. Morton DL, Wen DR, Wong JH et al (1992) Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 127:392-399
9. Morton DL, Thompson JF, Essner R et al. (1999) Validation of the accuracy of intraoperative lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: A multicenter trial. Multicenter Selective Lymphadenectomy Trial Group. Ann Surg 230:453-63 (discussion 63-5)
10. Morton DL, Cochran AJ, Thompson JF (2007) Sentinel node biopsy in melanoma (letter). N Engl J Med 356:419-420
11. Balch CM, Soong SJ, Murad TM, Ingalls AL, Maddox WA (1981) A multifactorial analysis of melanoma: III. Prognostic factors in melanoma patients with lymph node metastases (stage II). Ann Surg 193:377-388
12. Balch CM, Buzaid AC, Soong SJ et al (2001) Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma. J Clin Oncol 19:3635-3648
13. Morton DL, Thompson JF, Cochran AJ et al (2006) Sentinel-node biopsy or nodal observation in melanoma. N Engl J Med 355: 1307-1317
14. Morton DL, Cochran AJ, Thompson JF (2007) Authors' response to a letter to the editor re: Sentinel node biopsy for early-stage melanoma. Ann Surg 245:828-829
15. Faries MB, Thompson JF, Cochran A et al (2010) The impact on morbidity and length of stay of early versus delayed complete lymphadenectomy in melanoma: Results of the Multicenter Selective Lymphadenectomy Trial (I). Ann Surg Oncol 17: 3324-3329
16. Garreau JR, Faries M, Ye X (2009) Mood state and melanoma outcome in the Multicenter Selective Lymphadenectomy Trial. J Clin Oncol 27:Abstract 9603
17. Cochran AJ, Wen DR, Huang RR, Wang HJ, Elashoff R, Morton DL (2004) Prediction of metastatic melanoma in nonsentinel nodes and clinical outcome based on the primary melanoma and the sentinel node. Mod Pathol 17:747-755