Genetic variants in arhgef11 are associated with kidney injury in the dahl salt-sensitive rat

Hypertension

Volumn 60, Issue 5, 2012, Pages 1157-1168

  Williams, Jan M ^a   Johnson, Ashley C ^a   Stelloh, Cary ^c   Dreisbach, Albert W ^a   Franceschini, Nora ^b   Regner, Kevin R ^c   Townsend, Raymond R ^d   Roman, Richard J ^a   Garrett, Michael R ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b IL   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Dahl salt sensitive rats; fibrosis; genetic association studies; renal hemodynamics

Indexed keywords

FASUDIL;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARHGEF11 GENE; ARTICLE; CONGENIC STRAIN; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; GENE; GENE EXPRESSION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC VARIABILITY; GLOMERULUS FILTRATION RATE; HAPLOTYPE; HYPERTENSION; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; ANIMALS, CONGENIC; BLOOD PRESSURE; BLOTTING, WESTERN; CHROMOSOME MAPPING; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; KIDNEY; KIDNEY DISEASES; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN KINASE INHIBITORS; PROTEINURIA; QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED DAHL; RATS, INBRED SHR; RENAL CIRCULATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84868200082     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.112.199240     Document Type: Article

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