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Volumn 17, Issue 10, 2012, Pages 12449-12459

Acute toxicity and gastroprotective effect of the schiff base ligand 1H-indole-3-ethylene-5-nitrosalicylaldimine and its nickel (II) complex on ethanol induced gastric lesions in rats

Author keywords

Anti ulcer; Cimetidine; Histology; Metal complexes; Schiff bases; Tryptamine

Indexed keywords

1H INDOLE 3 ETHYLENE 5 NITROSALICYLALDIMINE; 1H-INDOLE-3-ETHYLENE-5-NITROSALICYLALDIMINE; ALCOHOL; INDOLE DERIVATIVE; LIGAND; NICKEL; PROTECTIVE AGENT; PROTON; SCHIFF BASE;

EID: 84868138295     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules171012449     Document Type: Article
Times cited : (25)

References (31)
  • 2
    • 27844463013 scopus 로고    scopus 로고
    • Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other diseases
    • Waseem, G.; Mark, T.H. Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other diseases. Life Sci. 2005, 78, 442-453.
    • (2005) Life Sci. , vol.78 , pp. 442-453
    • Waseem, G.1    Mark, T.H.2
  • 3
    • 0038060572 scopus 로고    scopus 로고
    • Cardioselective anti-ischemic ATP-sensitive potassium channel (KATP) openers: Benzopyranyl indoline and indole analogues
    • Lee, S.K.; Yi, K.Y.; Kim, S.K.; Suh, J.; Kim, N.J.; Yoo, S.; Lee, B.H.; Seo, H.W.; Kim, SO.; Lim, H. Cardioselective anti-ischemic ATP-sensitive potassium channel (KATP) openers: Benzopyranyl indoline and indole analogues. Eur. J. Med. Chem. 2003, 38, 459-471.
    • (2003) Eur. J. Med. Chem. , vol.38 , pp. 459-471
    • Lee, S.K.1    Yi, K.Y.2    Kim, S.K.3    Suh, J.4    Kim, N.J.5    Yoo, S.6    Lee, B.H.7    Seo, H.W.8    Kim, S.O.9    Lim, H.10
  • 4
    • 84868105419 scopus 로고    scopus 로고
    • Menadione protects gastric mucosa against ethanol-induced ulcers
    • Mohammad, T.; Moutaery, A.A. Menadione protects gastric mucosa against ethanol-induced ulcers. Exp. Tox. Path. 2005, 56, 119-129.
    • (2005) Exp. Tox. Path. , vol.56 , pp. 119-129
    • Mohammad, T.1    Moutaery, A.A.2
  • 5
    • 0023577472 scopus 로고
    • Biomimetic ferric ion carriers: A chiral analog of enterobactin, J
    • Tor, Y.; Libman, J.; Shanzer, A.; Lifson, S. Biomimetic ferric ion carriers: A chiral analog of enterobactin, J. Am Chem. Soc. 1987, 109, 6517-6518.
    • (1987) Am Chem. Soc. , vol.109 , pp. 6517-6518
    • Tor, Y.1    Libman, J.2    Shanzer, A.3    Lifson, S.4
  • 6
    • 0024806931 scopus 로고
    • X = Y-ZH systems as potential 1, 3-dipoles. Part 25. Intramolecular cycloaddition reactions of pyridoxal imines of s-alkenyl a-amino esters. A possible new approach to pyridoxal enzyme inhibition
    • Grigg, R.; Armstrong, P. X = Y-ZH systems as potential 1, 3-dipoles. Part 25. Intramolecular cycloaddition reactions of pyridoxal imines of s-alkenyl a-amino esters. A possible new approach to pyridoxal enzyme inhibition. Tetrahedron 1989, 45, 7581-7586.
    • (1989) Tetrahedron , vol.45 , pp. 7581-7586
    • Grigg, R.1    Armstrong, P.2
  • 8
    • 0016846997 scopus 로고
    • Jack Bean Urease (EC 3.5.1.5). Metalloenzyme. Simple biological role for nickel
    • Dixon, N.E.; Gazzola, C. Jack Bean Urease (EC 3.5.1.5). Metalloenzyme. Simple biological role for nickel. J. Am. Chem. Soc. 1975, 97, 4131-4133.
    • (1975) J. Am. Chem. Soc. , vol.97 , pp. 4131-4133
    • Dixon, N.E.1    Gazzola, C.2
  • 9
    • 0004186172 scopus 로고
    • Nickel and its role in biology
    • Dekker: New York, NY, USA
    • Sigel, H.; Sigel, A. Nickel and its role in biology. In Metal Ions in Biological Systems; Dekker: New York, NY, USA, 1989; Volume 23, pp. 359-402.
    • (1989) Metal Ions in Biological Systems , vol.23 , pp. 359-402
    • Sigel, H.1    Sigel, A.2
  • 10
    • 40649101197 scopus 로고    scopus 로고
    • Synthesis, structural characterization, antiradical and antidiabetic activities of copper (II) and zinc (II) Schiff base complexes derived from salicylaldehyde and β-alanine
    • Vancoa, J.; Marekb, J.; Trávnícekc, Z.; Racanskád, E.; Muselíke, J.; Švajlenováf, O. Synthesis, structural characterization, antiradical and antidiabetic activities of copper (II) and zinc (II) Schiff base complexes derived from salicylaldehyde and β-alanine. J. Inorg Biochem. 2008, 102, 595-605.
    • (2008) J. Inorg Biochem. , vol.102 , pp. 595-605
    • Vancoa, J.1    Marekb, J.2    Trávnícekc, Z.3    Racanskád, E.4    Muselíke, J.5    Švajlenováf, O.6
  • 11
    • 0016916478 scopus 로고
    • Copper chelates as possible active forms of the antiarthritic agents
    • Sorenson, J.R.J. Copper chelates as possible active forms of the antiarthritic agents. J. Med. Chem. 1976, 19, 135-148.
    • (1976) J. Med. Chem. , vol.19 , pp. 135-148
    • Sorenson, J.R.J.1
  • 12
    • 0006385786 scopus 로고
    • Role of low molecular weight copper complexes in the control of rheumatoid Arthritis
    • Helmut Sigel: New York, NY, USA
    • May, P.M.; Williams, D.R. Role of low molecular weight copper complexes in the control of rheumatoid Arthritis. In Metal Ions in Biological Systems; Helmut Sigel: New York, NY, USA, 1981; Volume 12, pp. 283-317.
    • (1981) Metal Ions in Biological Systems , vol.12 , pp. 283-317
    • May, P.M.1    Williams, D.R.2
  • 13
    • 70449732592 scopus 로고    scopus 로고
    • Synthesis structural characterization, and anti-ulcerogenic activity of Schiff bases derived from tryptamine, 5-chloro, 5-nitro, 3, 5 ditertiarybutyl salicylaldehyde and their nickel (II), copper (II) and zinc (II) complexes
    • Mohamed, M.I.; Hapipah, M.A.; Mahmood, A.A.; Ward, T.R. Synthesis, structural characterization, and anti-ulcerogenic activity of Schiff bases derived from tryptamine, 5-chloro, 5-nitro, 3, 5 ditertiarybutyl salicylaldehyde and their nickel (II), copper (II) and zinc (II) complexes. Polyhedron 2009, 28, 3993-3998.
    • (2009) Polyhedron , vol.28 , pp. 3993-3998
    • Mohamed, M.I.1    Hapipah, M.A.2    Mahmood, A.A.3    Ward, T.R.4
  • 14
    • 0025122228 scopus 로고
    • Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats
    • Kato, S.; Kawase, T.; Alderman, J.; Inatomi, N.; Lieber, C.S. Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats. Gastroenterology 1990, 98, 203-210.
    • (1990) Gastroenterology , vol.98 , pp. 203-210
    • Kato, S.1    Kawase, T.2    Alderman, J.3    Inatomi, N.4    Lieber, C.S.5
  • 15
    • 0028074476 scopus 로고
    • Alcohol and antioxidant systems
    • Nordmann, R. Alcohol and antioxidant systems. Alcohol 1994, 29, 513-522.
    • (1994) Alcohol , vol.29 , pp. 513-522
    • Nordmann, R.1
  • 16
    • 0028303711 scopus 로고
    • Mucus synthesis and sulfhydryl groups in cytoprotection mediated by dehydroleucodine, a sesquiterpene lactone
    • Guardia, T.; Guzman, J.; Pestchanker, M.J.; Guerreiro, E.; Giordano, O.S. Mucus synthesis and sulfhydryl groups in cytoprotection mediated by dehydroleucodine, a sesquiterpene lactone. J. Nat. Prod. 1994, 57, 507-509.
    • (1994) J. Nat. Prod. , vol.57 , pp. 507-509
    • Guardia, T.1    Guzman, J.2    Pestchanker, M.J.3    Guerreiro, E.4    Giordano, O.S.5
  • 18
    • 0031280490 scopus 로고    scopus 로고
    • Prostaglandins and nitric oxide in copper complex mediated protection against ethanol-induced gastric damage
    • Franco, L.; Doria, D. Prostaglandins and nitric oxide in copper complex mediated protection against ethanol-induced gastric damage. Pharmaco. Res. 1997, 36, 395-399.
    • (1997) Pharmaco. Res. , vol.36 , pp. 395-399
    • Franco, L.1    Doria, D.2
  • 20
    • 0034644721 scopus 로고    scopus 로고
    • Effect of Centella asiatica on ethanol induced gastric mucosal lesions in rats
    • Cheng, C.L.; Koo, M.W.L. Effect of Centella asiatica on ethanol induced gastric mucosal lesions in rats. Life Sci. 2000, 67, 2647-2653.
    • (2000) Life Sci. , vol.67 , pp. 2647-2653
    • Cheng, C.L.1    Koo, M.W.L.2
  • 21
    • 0023714486 scopus 로고
    • Microcirculatory stasis precedes tissue necrosis in ethanol-induced gastric mucosal injury in rat
    • Bou-Abboud, C.F.; Wayland, H.; Panlsen, G.; Guth, P.H. Microcirculatory stasis precedes tissue necrosis in ethanol-induced gastric mucosal injury in rat. Dig. Dis. Sci. 1988, 33, 872-877.
    • (1988) Dig. Dis. Sci. , vol.33 , pp. 872-877
    • Bou-Abboud, C.F.1    Wayland, H.2    Panlsen, G.3    Guth, P.H.4
  • 22
    • 0029878339 scopus 로고    scopus 로고
    • Effects of teminoprazole, omeprazole and sucralfate on indomethacin-induced delayed healing of kissing gastric ulcers in rats
    • Tsukimi, Y.; Nozue, C.; Okabe, S. Effects of teminoprazole, omeprazole and sucralfate on indomethacin-induced delayed healing of kissing gastric ulcers in rats. J. Gastroen. Hepatol. 1996, 11, 335-340.
    • (1996) J. Gastroen. Hepatol. , vol.11 , pp. 335-340
    • Tsukimi, Y.1    Nozue, C.2    Okabe, S.3
  • 24
    • 0027256348 scopus 로고
    • The gastric antiulcer effects of the leaves of the neem tree
    • Garg, G.P.; Nigam, S.K.; Ogle, C.W. The gastric antiulcer effects of the leaves of the neem tree. Planta Med. 1993, 59, 215-217.
    • (1993) Planta Med. , vol.59 , pp. 215-217
    • Garg, G.P.1    Nigam, S.K.2    Ogle, C.W.3
  • 25
    • 0018637521 scopus 로고
    • Cytoprotection by prostaglandins in rats, Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl and thermal injury
    • Robert, A.; Nezamis, J.E.; Lancaster, C.; Hanchar, A.J. Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl and thermal injury. Gastroenterology 1979, 77, 433-443.
    • (1979) Gastroenterology , vol.77 , pp. 433-443
    • Robert, A.1    Nezamis, J.E.2    Lancaster, C.3    Hanchar, A.J.4
  • 26
    • 0032145420 scopus 로고    scopus 로고
    • Gastroprotective effect of Copaifera langsdorffii oleo-resin on experimental gastric ulcer models in rats
    • Paiva, L.A.F.; Rao, V.S.N.; Gramosa, N.V.; Silveira, F.R. Gastroprotective effect of Copaifera langsdorffii oleo-resin on experimental gastric ulcer models in rats. J. Ethnopharm. 1998, 62, 73-78.
    • (1998) J. Ethnopharm. , vol.62 , pp. 73-78
    • Paiva, L.A.F.1    Rao, V.S.N.2    Gramosa, N.V.3    Silveira, F.R.4
  • 28
    • 0028891077 scopus 로고
    • Methyl angolensate: The antiulcer agent of stem bark of etandrophragma angolense
    • Njar, V.C.O.; Adesanwo, J.K.; Raji, Y. Methyl Angolensate: The antiulcer agent of stem bark of Etandrophragma angolense. Planta Med. 1995, 61, 91-92.
    • (1995) Planta Med. , vol.61 , pp. 91-92
    • Njar, V.C.O.1    Adesanwo, J.K.2    Raji, Y.3
  • 30
    • 79960871369 scopus 로고    scopus 로고
    • accessed on 15 October 2012
    • OECD guideline for testing of chemicals. Available online: http://iccvam.niehs.nih.gov/SuppDocs/FedDocs/OECD/OECD-GL425.pdf (accessed on 15 October 2012).
    • OECD Guideline for Testing of Shemicals


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