Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transport

Journal of Neuroscience

Volumn 32, Issue 44, 2012, Pages 15495-15510

  Mitchell, David J ^a   Blasier, Kiev R ^a   Jeffery, Erin D ^b   Ross, Mitchell W ^a   Pullikuth, Ashok K ^c   Suo, Dong ^b   Park, Juyeon ^b   Russell Smiley, W ^a   Lo, Kevin W H ^a   Shabanowitz, Jeffrey ^b   Deppmann, Christopher D ^b   Trinidad, Jonathan C ^d,e   Hunt, Donald F ^b   Catling, Andrew D ^c   Pfister, K Kevin ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CYTOPLASMIC DYNEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROTROPHIN; PROTEIN TYROSINE KINASE A; RAB7 PROTEIN;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; ENDOSOME; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; IMMUNOPRECIPITATION; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; RETROGRADE NERVE FIBER TRANSPORT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; AXONAL TRANSPORT; BLOTTING, WESTERN; CELL MEMBRANE; CELL SURVIVAL; CYTOPLASM; DYNEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOSOMES; ENZYME ACTIVATION; MAP KINASE SIGNALING SYSTEM; NERVE GROWTH FACTOR; NERVE GROWTH FACTORS; NEURONS; ORGANELLES; PC12 CELLS; PHOSPHORYLATION; PLASMIDS; RATS; RECEPTOR, TRKA; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84868130014     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5599-11.2012     Document Type: Article

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