Bupropion therapy in pregnancy and the occurrence of cardiovascular malformations in infants

Pharmacoepidemiology and Drug Safety

Volumn 21, Issue 11, 2012, Pages 1240-1242

  Thyagarajan, Veena ^a   Robin Clifford, C ^b   Wurst, Keele E ^c   Ephross, Sara A ^c   Seeger, John D ^b,d  

^a OptumInsight ^*

^b OPTUM   (United States)

^c GLAXOSMITHKLINE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; ANTIDEPRESSANT AGENT;

CARDIOVASCULAR MALFORMATION; CLINICAL ASSESSMENT; COHORT ANALYSIS; DELIVERY; ENVIRONMENTAL EXPOSURE; FIRST TRIMESTER PREGNANCY; HEART LEFT VENTRICLE OUTFLOW TRACT OBSTRUCTION; HUMAN; INFANT; LETTER; MONOTHERAPY; PATENT DUCTUS ARTERIOSUS; PATENT FORAMEN OVALE; PREGNANCY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SMOKING;

ADOLESCENT; ADULT; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BUPROPION; CARDIOVASCULAR ABNORMALITIES; CHILD; COHORT STUDIES; FEMALE; HUMANS; INFANT, NEWBORN; LOGISTIC MODELS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PRENATAL EXPOSURE DELAYED EFFECTS; PREVALENCE; YOUNG ADULT;

EID: 84868115924     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.3271     Document Type: Letter

References (6)

1. GlaxoSmithKline. Wellbutrin [package insert]. 2011. Research Triangle Park, NC.
2. GlaxoSmithKline. Zyban [package insert]. 2011. Research Triangle Park, NC.
3. Cole JA, Modell JG, Haight BR, et al. Bupropion in pregnancy and the prevalence of congenital malformations. Pharmacoepidemiol Drug Saf 2007; 16: 474-484. DOI: 10.1002/pds.1296
4. Alwan S, Reefhuis J, Botto LD, et al. Maternal use of bupropion and risk for congenital heart defects. Am J Obstet Gynecol 2010; 202: 1.e1-1.e6.
5. Botto LD, Lin AE, Riehle-Colarusso T, et al. Seeking causes: classifying and evaluating congenital heart defects in etiologic studies. Birth Defects Research 2007; 79(Part A): 714-727.
6. Guidelines for good pharmacoepidemiology practices (GPP). Pharmacoepidemiol Drug Saf 2008; 17(2): 200-208.