Clinical implications of a recent adjustment to the high-sensitivity cardiac troponin T assay: User beware

Clinical Chemistry

Volumn 58, Issue 11, 2012, Pages 1599-1600

  Apple, Fred S ^a,b   Jaffe, Allan S ^c  

^a HENNEPIN COUNTY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TROPONIN T;

ACUTE CORONARY SYNDROME; CALCULATION; CALIBRATION; DIAGNOSTIC ACCURACY; EMERGENCY CARE; HEART INFARCTION; HUMAN; LETTER; SENSITIVITY ANALYSIS;

CALIBRATION; HUMANS; QUALITY ASSURANCE, HEALTH CARE; QUALITY CONTROL; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; TROPONIN T;

EID: 84868105856     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2012.194985     Document Type: Letter

References (5)

1. Omland T, De Lemos JA, Sabatine MS, Christophi CA, Rice MM, Jablonski KA, et al, and the Prevention of Events with Angiotensin Converting Enzyme Inhibition (PEACE) Trial Investigators. A sensitive cardiac troponin T assay in stable coronary artery disease. N Engl J Med 2009;361:2538-47.
2. Giannitsis E, Kurz K, Hallermayer K, Jarausch J, Jaffe AS, Katus HA. Analytical validation of a high-sensitivity cardiac troponin T assay. Clin Chem 2010;56:254-61.
3. Saenger AK, Beyrau R, Braun S, Cooray R, Dolci A, Freidank H, et al. Multicenter analytical evaluation of a high-sensitivity troponin T assay. Clin Chim Acta 2011;412:748-54.
4. De Lemos JA, Drazner MH, Omland T, Ayers CR, Khera A, Rohatgi A, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA 2010;304:2503-12.
5. Reichlin T, Hochholzer W, Bassetti S, Steuer S, Stelzig C, Hartwiger S, et al. Early diagnosis of myocardial infarction with sensitive cardiac troponin assays. N Engl J Med 2009;361:858-67.