Acquired xanthine dehydrogenase expression shortens survival in patients with resected adenocarcinoma of lung

Tumor Biology

Volumn 33, Issue 5, 2012, Pages 1727-1732

  Konno, Hayato ^a   Minamiya, Yoshihiro ^a   Saito, Hajime ^a   Imai, Kazuhiro ^a   Kawaharada, Yasushi ^a   Motoyama, Satoru ^a   Ogawa, Jun Ichi ^a  

^a AKITA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Adenocarcinoma; Lung cancer; Prognosis; Xanthine dehydrogenase; Xanthine oxidase

Indexed keywords

ANTINEOPLASTIC AGENT; MESSENGER RNA; PLATINUM COMPLEX; UFT; XANTHINE DEHYDROGENASE;

ADJUVANT THERAPY; ADULT; ARTICLE; CANCER PROGNOSIS; CANCER SURVIVAL; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE FREE SURVIVAL; FEMALE; HAZARD RATIO; HUMAN; HUMAN TISSUE; LOG RANK TEST; LUNG ADENOCARCINOMA; LUNG PARENCHYMA; LUNG RESECTION; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SURVIVAL RATE;

EID: 84868090574     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-012-0431-2     Document Type: Article

References (26)

1. Boueiz A, Damarla M, Hassoun PM. Xanthine oxidoreductase in respiratory and cardiovascular disorders. Am J Physiol Lung Cell Mol Physiol. 2008;294:L830-40.
2. McCord JM. Oxygen-derived radicals: a link between reperfusion injury and inflammation. Fed Proc. 1987;46(7):2402-6.
3. Parks DA, Granger DN. Xanthine oxidase: biochemistry and physiology. Acta Physiol Scand Suppl. 1986;548:87-99.
4. Ashraf M, Samra ZQ. Subcellular distribution of xanthine oxidase during cardiac ischemia and reperfusion: an immunocytochemical study. J Submicrosc Cytol Pathol. 1993;25:193-201.
5. Yokoyama Y, Beckman JS, Beckman TK, Wheat JK, Cash TG, Freeman BA, Parks DA. Circulating xanthine oxidase: potential mediator of ischemic injury. Am J Physiol. 1990;258:G564-G70.
6. Samra ZQ, Siddique Z. Distribution of xanthine oxidase during calcium paradox conditions of rat heart. Punjab Univ J Zool. 1998;13:89-98.
7. Halliwell B, Gutteridge JM, Cross CE. Free radicals, antioxidants, and human disease: where are we now? J Lab Clin Med. 1992;119:598-620.
8. Samra ZQ, Pervaiz S, Shaheen S, Dar N, Athar MA. Determination of oxygen derived free radicals producer (xanthine oxidase) and scavenger (paraoxonase1) enzymes and lipid parameters in different cancer patients. Clin Lab. 2011;57:741-7.
9. Nishikawa M. Reactive oxygen species in tumor metastasis. Cancer Lett. 2008;266:53-9.
10. Dizdaroglu M, Jaruga P, Birincioglu M, Rodriguez H. Free radical-induced damage to DNA: mechanisms and measurement. Free Radic Biol Med. 2002;32:1102-15.
11. Klaunig JE, Kamendulis LM. The role of oxidative stress in carcinogenesis. Annu Rev Pharmacol Toxicol. 2004;44:239-67.
12. Wright RM, McManaman JL, Repine JE. Alcohol-induced breast cancer: a proposed mechanism. Free Radic Biol Med. 1999;26:348-54.
13. Castro GD, Delgado de Layño AM, Costantini MH, Castro JA. Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer. Toxicology. 2001;160:11-8.
14. Kaynar H, Meral M, Turhan H, Keles M, Celik G, Akcay F. Glutathione peroxidase, glutathione-S-transferase, catalase, xanthine oxidase, Cu-Zn superoxide dismutase activities, total glutathione, nitric oxide, and malondialdehyde levels in erythrocytes of patients with small cell and non-small cell lung cancer. Cancer Lett. 2005;227:133-9.
15. Tsao SM, Yin MC, Liu WH. Oxidant stress and B vitamins status in patients with non-small cell lung cancer. Nutr Cancer. 2007;59:8-13.
16. Linder N, Rapola J, Raivio KO. Cellular expression of xanthine oxidoreductase protein in normal human tissues. Lab Investig. 1999;79:967-74.
17. Linder N, Lundin J, Isola J, Lundin M, Raivio KO, Joensuu H. Down-regulated xanthine oxidoreductase is a feature of aggressive breast cancer. Clin Cancer Res. 2005;11:4372-81.
18. Linder N, Martelin E, Lundin M, Louhimo J, Nordling S, Haglund C, Lundin J. Xanthine oxidoreductaseclinical significance in colorectal cancer and in vitro expression of the protein in human colon cancer cells. Eur J Cancer. 2009;45:648-55.
19. Linder N, Haglund C, Lundin M, Nordling S, Ristimäki A, Kokkola A, Mrena J, Wiksten JP, Lundin J. Decreased xanthine oxidoreductase is a predictor of poor prognosis in early-stage gastric cancer. J Clin Pathol. 2006;59:965-71.
20. Kim AW, Batus M, Myint R, Fidler MJ, Basu S, Bonomi P, Faber LP, Wightman SC, Warren WH, McIntire M, Arvanitis LD, Gattuso P, Xu X, Liptay MJ. Prognostic value of xanthine oxidoreductase expression in patients with non-small cell lung cancer. Lung Cancer. 2011;71:186-90.
21. Sobin L, Wittekind CH, editors. TNM classification of malignant tumours. 6th ed. New York: Wiley; 2002. p. 99-103.
22. Oesterreich S. Scaffold attachment factors SAFB1 and SAFB2: innocent bystanders or critical players in breast tumorigenesis? J Cell Biochem. 2003;90:653-61.
23. Lin J, Xu P, LaVallee P, Hoidal JR. Identification of proteins binding to E-Box/Ku86 sites and function of the tumor suppressor SAFB1 in transcriptional regulation of the human xanthine oxidoreductase gene. J Biol Chem. 2008;283:29681-9.
24. Taibi G, Carruba G, Cocciadiferro L, Granata OM, Nicotra CM. Low levels of both xanthine dehydrogenase and cellular retinol binding protein are responsible for retinoic acid deficiency in malignant human mammary epithelial cells. Ann N Y Acad Sci. 2009;1155:268-72.
25. Tsukioka T, Nishiyama N, Iwata T, Nagano K, Tei K, Suehiro S. Preoperative serum oxidative stress marker as a strong indicator of nodal involvement in clinical stage I lung adenocarcinoma. Int J Clin Oncol. 2011. doi: 10.1007/s10147-011-0283-6
26. Mongaret C, Alexandre J, Thomas-Schoemann A, Bermudez E, Chéreau C, Nicco C, Goldwasser F, Weill B, Batteux F, Lemare F. Tumor invasion induced by oxidative stress is dependent on membrane ADAM 9 protein and its secreted form. Int J Cancer. 2011;129:791-8.