Do basophile structures as age dependent phenomenon indicate small vessel wall damage?

Microvascular Research

Volumn 84, Issue 3, 2012, Pages 375-377

  Schreiber, Stefanie ^a   Garz, Cornelia ^a   Bueche, Celine ^a   Kuester, Doerthe ^a   Kropf, Siegfried ^a   Westphal, Sabine ^a   Isermann, Berend ^a   Oldag, Andreas ^a   Heinze, Hans Jochen ^a,b,c   Goertler, Michael ^a   Reymann, Klaus ^b,c   Braun, Holger ^c  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AGE; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIOLE; ARTERY WALL; ARTICLE; BASAL GANGLION; BASOPHIL; BLOOD BRAIN BARRIER; BRAIN ARTERY; BRAIN CAPILLARY; BRAIN CORTEX; CELL STRUCTURE; CELL TRANSFORMATION; CEREBELLUM; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; CORPUS CALLOSUM; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT;

AGARICUS; AGE FACTORS; ANIMALS; ANTIGENS, CD11C; ARTERIOLES; BETA-GLUCANS; BLOOD-BRAIN BARRIER; BRAIN; CAPILLARIES; CYTOKINES; DENDRITIC CELLS; ENDOTHELIUM, VASCULAR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTERFERON-GAMMA; LECTINS, C-TYPE; MALE; MICE; MICROCIRCULATION; RATS; SPLEEN;

EID: 84868090102     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2012.07.007     Document Type: Article

References (5)

1. Braun H., Bueche C., Garz C., Oldag A., Heinze H.-J., Goertler M., Reymann K.G., Schreiber S. Stases are associated with blood-brain barrier damage and a restricted activation of coagulation in SHRSP. J. Neurol. Sci. 2012, (Jul 23). (Epub ahead of print).
2. Grinberg L.T., Thal D.R. Vascular pathology in the aged human brain. Acta Neuropathol. 2010, 119:277-290.
3. Hainsworth A.H., Markus H.S. Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review. J. Cereb. Blood Flow Metab. 2008, 28:1877-1891.
4. Schreiber S., Bueche C.Z., Garz C., Kropf S., Kuester D., Amann K., Heinze H.J., Goertler M., Reymann K.G., Braun H. Kidney pathology precedes and predicts the pathological cascade of cerebrovascular lesions in stroke prone rats. PLoS One 2011, 6:e26287.
5. Schreiber S., Bueche C.Z., Garz C., Kropf S., Angenstein F., Goldschmidt J., Neumann J., Heinze H.J., Goertler M., Reymann K.G., Braun H. The pathologic cascade of cerebrovascular lesions in SHRSP: is erythrocyte accumulation an early phase?. J. Cereb. Blood Flow Metab. 2012, 32:278-290.