Randomized controlled trial of the safety and efficacy of daptomycin versus standard-of-care therapy for management of patients with osteomyelitis associated with prosthetic devices undergoing two-stage revision arthroplasty

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 11, 2012, Pages 5626-5632

  Byren, Ivor ^a   Rege, Shruta ^b   Campanaro, Ed ^b   Yankelev, Sara ^b   Anastasiou, Diane ^b   Kuropatkin, Gennady ^c   Evans, Richard ^d,e  

^a NUFFIELD ORTHOPAEDIC CENTRE   (United Kingdom)

^b CUBIST PHARMACEUTICALS INC   (United States)

^c Samara Region Clinical Hospital   (Russian Federation)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^e UNIVERSITY OF MISSOURI KANSAS CITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE; DAPTOMYCIN; PENICILLIN G; TEICOPLANIN; VANCOMYCIN;

ADULT; ARTHROPLASTY; ARTICLE; CONSTIPATION; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DEEP VEIN THROMBOSIS; DEVICE REMOVAL; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SAFETY; DYSPNEA; EDEMA; FEMALE; FEVER; HEALTH CARE QUALITY; HUMAN; HYPOTENSION; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MULTICENTER STUDY; NAUSEA; OPEN STUDY; OSTEOMYELITIS; PERIPHERAL EDEMA; PERIPROSTHETIC JOINT INFECTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PRURITUS; RANDOMIZED CONTROLLED TRIAL; RASH; REIMPLANTATION; REOPERATION; SIDE EFFECT; URINARY TRACT INFECTION;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; ARTHROPLASTY, REPLACEMENT, HIP; ARTHROPLASTY, REPLACEMENT, KNEE; BIOLOGICAL MARKERS; CREATINE KINASE; DAPTOMYCIN; DRUG ADMINISTRATION SCHEDULE; FEMALE; HIP PROSTHESIS; HUMANS; KNEE PROSTHESIS; MALE; MIDDLE AGED; OSTEOMYELITIS; PENICILLINS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SYNOVIAL FLUID; TREATMENT OUTCOME; VANCOMYCIN;

EID: 84868031080     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00038-12     Document Type: Article

References (26)

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