Imaging properties of small-pixel spectroscopic x-ray detectors based on cadmium telluride sensors

Physics in Medicine and Biology

Volumn 57, Issue 21, 2012, Pages 6743-6759

  Koenig, Thomas ^a,b   Schulze, Julia ^a   Zuber, Marcus ^a   Rink, Kristian ^a   Butzer, Jochen ^b   Hamann, Elias ^b,c   Cecilia, Angelica ^b,c   Zwerger, Andreas ^c   Fauler, Alex ^c   Fiederle, Michael ^c   Oelfke, Uwe ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b KARLSRUHE INSTITUTE OF TECHNOLOGY   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AVERAGE NUMBERS; CDTE; CHARACTERISTIC X RAYS; CONTRAST AGENT; COUNT RATES; DETECTIVE QUANTUM EFFICIENCY; ENERGY RANGES; IMAGING PROPERTIES; MATERIAL DISCRIMINATION; MEAN-FREE PATH LENGTH; MEDIPIX2; MULTI-CHIP; PEAK WIDTHS; PHOTON COUNTING DETECTORS; PIXEL PITCH; REDUCED ENERGY; SATURATION EFFECTS; SENSOR MATERIALS; SPATIAL FREQUENCY; X-RAY DETECTOR; X-RAY FLUX; XRAY IMAGING;

CADMIUM TELLURIDE; GADOLINIUM; IODINE; PHOTONS; SENSORS;

PIXELS;

CADMIUM DERIVATIVE; CADMIUM TELLURIDE; CONTRAST MEDIUM; DIAGNOSTIC AGENT; TELLURIUM; WATER;

ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; IMAGE PROCESSING; IMAGE QUALITY; METHODOLOGY; RADIOMETRY; TEMPERATURE;

CADMIUM COMPOUNDS; CONTRAST MEDIA; IMAGE PROCESSING, COMPUTER-ASSISTED; PHANTOMS, IMAGING; RADIOMETRY; TELLURIUM; TEMPERATURE; TOMOGRAPHY, X-RAY COMPUTED; WATER;

EID: 84868028114     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/57/21/6743     Document Type: Article

References (33)

1. Alvarez R E and Macovski A 1976 Energy-selective reconstructions in x-ray computerised tomography Phys. Med. Biol. 21 733-44
2. Bale D S and Szeles C 2008 Nature of polarization in wide-bandgap semiconductor detectors under high-flux irradiation: application to semi-insulating Cd(1 x) Znx Te Phys. Rev. B 77 35205
3. Ballabriga R, Campbell M, Heijne E H M, Llopart X and Tlustos L 2007 The medipix3 prototype, a pixel readout chip working in single photon counting mode with improved spectrometric performance IEEE Nuclear Science Symp. Conf. Record (2006) pp 3557-61
4. Barber W C, Nygard E, Wessel J C, Malakhov N, Wawrzyniak G, Hartsough N E, Gandhi T, Beck T J, Taguchi K and Iwanczyk J S 2009 Large area photon counting x-ray imaging arrays for clinical dual-energy applications IEEE Nuclear Science Symp. Conf. Record pp 3029-31
5. Brooks R A 1977 A quantitative theory of the Hounsfield unit and its application to dual energy scanning J. Comput. Assist. Tomogr. 1 487-93 (Pubitemid 8228115)
6. Butler A P H, Anderson N G, Tipples R, Cook N, Watts R, Meyer J, Bell A J, Melzer T R and Butler P H 2008 Bio-medical x-ray imaging with spectroscopic pixel detectors Nucl. Instrum. Methods A 591 141-6
7. Campbell M, Heijne E H M, Meddeler G, Pernigotti E and Snoeys W 1998 Readout for a 64 × 64 pixel matrix with 15-bit single photon counting IEEE Trans. Nucl. Sci. 45 751-3 (Pubitemid 128739106)
8. Cecilia A et al 2011 Investigation of crystallographic and detection properties of CdTe at the ANKA synchrotron light source J. Instrum. 6 P10016
9. Coleman A J and Sinclair M 1985 A beam-hardening correction using dual-energy computed tomography Phys. Med. Biol. 30 1251-6 (Pubitemid 16234027)
10. Cormode D P et al 2010 Atherosclerotic plaque composition: analysis with multicolor CT and targeted gold nanoparticles1 Radiology 256 774-82
11. Firsching M, Butler A P, Scott N, Anderson N G, Michel T and Anton G 2009 Contrast agent recognition in small animal CT using the medipix2 detector Nucl. Instrum. Methods A 607 179-82
12. Holy T, Jakubek J, Pospisil S, Uher J, Vavrik D and Vykydal Z 2006 Data acquisition and processing software package for medipix2 Nucl. Instrum. Methods A 563 254-8 (Pubitemid 43867003)
13. Kak A C and Slaney M 2001 Principles of Computerized Tomographic Imaging (Philadelphia, PA: SIAM)
14. Kawrakow I 2000 Accurate condensed history Monte Carlo simulation of electron transport: I. EGSnrc the new EGS4 version Med. Phys. 27 485 (Pubitemid 30171797)
15. Kawrakow I, Rogers D W O and Walters B R B 2004 Large efficiency improvements in BEAMnrc using directional bremsstrahlung splitting Med. Phys. 31 2883 (Pubitemid 39431018)
16. Koenig T 2011 Exploring coherent phenomena and energy discrimination in x-ray imaging PhD Thesis University of Heidelberg, Germany (available at http://archiv.ub.uni-heidelberg.de/volltextserver/volltexte/2011/11933/pdf/ koenig-phd-final.pdf)
17. Koenig T, Zuber M, Zwerger A, Schuenke P, Nill S, Fauler A, Fiederle M and Oelfke U 2011a A comparison of various strategies to equalize the lower energy thresholds of a CdTe medipix2 hexa detector for x-ray imaging applications J. Instrum. 6 C01074
18. Koenig T, Zwerger A, Zuber M, Schuenke P, Nill S, Guni E, Fauler A, Fiederle M and Oelfke U 2011b On the energy response function of a CdTe medipix2 hexa detector Nucl. Instrum. Methods A 648 S265-8
19. Kraus V, Holik M, Jakubek J, Kroupa M, Soukup P and Vykydal Z 2011 FITPix fast interface for timepix pixel detectors J. Instrum. 6 C01079
20. Llopart X 2007 Design and characterization of 64K pixels chips working in single photon processing mode PhD Thesis Mid Sweden University (available at http://miun.diva-portal.org/smash/record.jsf?pid=diva2:2019)
21. Llopart X, Campbell M, Dinapoli R, San Segundo D and Pernigotti E 2002 Medipix2: a 64-k pixel readout chip with 55-μm square elements working in single photon counting mode IEEE Trans. Nucl. Sci. 49 2279 (Pubitemid 35443088)
22. Maa C, Meyer E and Kachelrie M 2011 Exact dual energy material decomposition from inconsistent rays (MDIR) Med. Phys. 38 691
23. Michel T et al 2006 A fundamental method to determine the signal-to-noise ratio (SNR) and detective quantum efficiency (DQE) for a photon counting pixel detector Nucl. Instrum. Methods A 568 799-802 (Pubitemid 44716455)
24. Niederlöhner D 2006 Untersuchungen zur Energiewichtung in der medizinischen Roentgenbildgebung mit dem Medipix2-Detektor PhD Thesis University Erlangen-Nuernberg (available at http://www.pi4.nat.uni-erlangen.de/novel- detectors/publications/phd-diplomathesis/niederloehner-dr.pdf)
25. Schlomka J et al 2008 Experimental feasibility of multi-energy photon-counting k-edge imaging in pre-clinical computed tomography Phys. Med. Biol. 53 4031-47
26. Shikhaliev P M 2008 Energy-resolved computed tomography: first experimental results Phys. Med. Biol. 53 5595-613
27. Shikhaliev P M and Fritz S G 2011 Photon counting spectral CT versus conventional CT: comparative evaluation for breast imaging application Phys. Med. Biol. 56 1905-30
28. Shikhaliev P M, Fritz S G and Chapman J W 2009 Photon counting multienergy x-ray imaging: effect of the characteristic x rays on detector performance Med. Phys. 36 5107
29. Spartiotis K, Durrant R, Leppanen A, Lohman H, Mannisto O, Pantsar T, Pyyhtia J and Schulman T 2008 X- and gamma ray imaging systems based on CdTe-CMOS detector technology IEEE Nuclear Science Symp. Conf. Record pp 518-22
30. Spieler H 2006 Semiconductor Detector Systems (Oxford: Oxford University Press)
31. Strassburg M, Schroeter C and Hackenschmied P 2011 CdTe/CZT under high flux irradiation J. Instrum. 6 C01055
32. Vykydal Z, Jakubek J and Pospisil S 2006 USB interface for medipix2 pixel device enabling energy and position-sensitive detection of heavy charged particles Nucl. Instrum. Methods A 563 112-5 (Pubitemid 43866987)
33. Yveborg M, Danielsson M and Bornefalk H 2012 Performance evaluation of a sub-millimetre spectrally resolved CT system on high- and low-frequency imaging tasks: a simulation Phys. Med. Biol. 57 2373-91