A genetically encoded metabolite sensor for malonyl-CoA

Chemistry and Biology

Volumn 19, Issue 10, 2012, Pages 1333-1339

  Ellis, Jessica M ^a   Wolfgang, Michael J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIM KINASE 1; MALONYL COENZYME A; MALONYL COENZYME A DECARBOXYLASE;

ARTICLE; BIOSENSOR; CONCENTRATION (PARAMETERS); DNA BINDING; ENZYME PHOSPHORYLATION; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENE ACTIVITY; GENETIC CODE; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BACILLUS SUBTILIS; BACTERIAL PROTEINS; BIOSENSING TECHNIQUES; CARBOXY-LYASES; CERCOPITHECUS AETHIOPS; COS CELLS; FATTY ACIDS; GENES, REPORTER; LIM KINASES; LUMINESCENT PROTEINS; MALONYL COENZYME A; RECOMBINANT FUSION PROTEINS;

BACILLUS SUBTILIS; MAMMALIA;

EID: 84868024193     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2012.08.018     Document Type: Article

References (28)

1. J. An, D.M. Muoio, M. Shiota, Y. Fujimoto, G.W. Cline, G.I. Shulman, T.R. Koves, R. Stevens, D. Millington, and C.B. Newgard Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance Nat. Med. 10 2004 268 274 (Pubitemid 38667617)
2. J. Berg, Y.P. Hung, and G. Yellen A genetically encoded fluorescent reporter of ATP:ADP ratio Nat. Methods 6 2009 161 166
3. J.S. Boehm, J.J. Zhao, J. Yao, S.Y. Kim, R. Firestein, I.F. Dunn, S.K. Sjostrom, L.A. Garraway, S. Weremowicz, and A.L. Richardson Integrative genomic approaches identify IKBKE as a breast cancer oncogene Cell 129 2007 1065 1079 (Pubitemid 46891036)
4. M. Buzzai, D.E. Bauer, R.G. Jones, R.J. Deberardinis, G. Hatzivassiliou, R.L. Elstrom, and C.B. Thompson The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation Oncogene 24 2005 4165 4173 (Pubitemid 40961771)
5. M. Endo, K. Ohashi, and K. Mizuno LIM kinase and slingshot are critical for neurite extension J. Biol. Chem. 282 2007 13692 13702 (Pubitemid 47100568)
6. J.C. Ewald, S. Reich, S. Baumann, W.B. Frommer, and N. Zamboni Engineering genetically encoded nanosensors for real-time in vivo measurements of citrate concentrations PLoS ONE 6 2011 e28245
7. M. Fehr, W.B. Frommer, and S. Lalonde Visualization of maltose uptake in living yeast cells by fluorescent nanosensors Proc. Natl. Acad. Sci. USA 99 2002 9846 9851 (Pubitemid 34831135)
8. M. Fehr, S. Lalonde, I. Lager, M.W. Wolff, and W.B. Frommer In vivo imaging of the dynamics of glucose uptake in the cytosol of COS-7 cells by fluorescent nanosensors J. Biol. Chem. 278 2003 19127 19133 (Pubitemid 36799301)
9. M. Fehr, S. Lalonde, D.W. Ehrhardt, and W.B. Frommer Live imaging of glucose homeostasis in nuclei of COS-7 cells J. Fluoresc. 14 2004 603 609
10. M. Fehr, H. Takanaga, D.W. Ehrhardt, and W.B. Frommer Evidence for high-capacity bidirectional glucose transport across the endoplasmic reticulum membrane by genetically encoded fluorescence resonance energy transfer nanosensors Mol. Cell. Biol. 25 2005 11102 11112 (Pubitemid 41747150)
11. J. Folch, M. Lees, and G.H. Sloane Stanley A simple method for the isolation and purification of total lipides from animal tissues J. Biol. Chem. 226 1957 497 509
12. S.R. Hamilton, D. Stapleton, J.B. O'Donnell Jr.; J.T. Kung, S.R. Dalal, B.E. Kemp, and L.A. Witters An activating mutation in the gamma1 subunit of the AMP-activated protein kinase FEBS Lett. 500 2001 163 168 (Pubitemid 32607553)
13. Z. Hu, Y. Dai, M. Prentki, S. Chohnan, and M.D. Lane A role for hypothalamic malonyl-CoA in the control of food intake J. Biol. Chem. 280 2005 39681 39683 (Pubitemid 41779099)
14. B.B. Kahn, T. Alquier, D. Carling, and D.G. Hardie AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism Cell Metab. 1 2005 15 25 (Pubitemid 43960587)
15. I. Lager, M. Fehr, W.B. Frommer, and S. Lalonde Development of a fluorescent nanosensor for ribose FEBS Lett. 553 2003 85 89 (Pubitemid 37206329)
16. I. Lager, L.L. Looger, M. Hilpert, S. Lalonde, and W.B. Frommer Conversion of a putative Agrobacterium sugar-binding protein into a FRET sensor with high selectivity for sucrose J. Biol. Chem. 281 2006 30875 30883 (Pubitemid 44582142)
17. P. Lee, G. Morley, Q. Huang, A. Fischer, S. Seiler, J.W. Horner, S. Factor, D. Vaidya, J. Jalife, and G.I. Fishman Conditional lineage ablation to model human diseases Proc. Natl. Acad. Sci. USA 95 1998 11371 11376 (Pubitemid 28450135)
18. X.D. Li, L. Sun, R.B. Seth, G. Pineda, and Z.J. Chen Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity Proc. Natl. Acad. Sci. USA 102 2005 17717 17722 (Pubitemid 41803563)
19. M. Mayford, M.E. Bach, Y.Y. Huang, L. Wang, R.D. Hawkins, and E.R. Kandel Control of memory formation through regulated expression of a CaMKII transgene Science 274 1996 1678 1683 (Pubitemid 26414891)
20. H. Nguyen, M. Rendl, and E. Fuchs Tcf3 governs stem cell features and represses cell fate determination in skin Cell 127 2006 171 183 (Pubitemid 44466637)
21. S. Okumoto, L.L. Looger, K.D. Micheva, R.J. Reimer, S.J. Smith, and W.B. Frommer Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors Proc. Natl. Acad. Sci. USA 102 2005 8740 8745 (Pubitemid 40862805)
22. A.A. Reamy, and M.J. Wolfgang Carnitine palmitoyltransferase-1c gain-of-function in the brain results in postnatal microencephaly J. Neurochem. 118 2011 388 398
23. S. Rodriguez, and M.J. Wolfgang Targeted chemical-genetic regulation of protein stability in vivo Chem. Biol. 19 2012 391 398
24. G.E. Schujman, L. Paoletti, A.D. Grossman, and D. de Mendoza FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis Dev. Cell 4 2003 663 672 (Pubitemid 36564897)
25. G.E. Schujman, M. Guerin, A. Buschiazzo, F. Schaeffer, L.I. Llarrull, G. Reh, A.J. Vila, P.M. Alzari, and D. de Mendoza Structural basis of lipid biosynthesis regulation in Gram-positive bacteria EMBO J. 25 2006 4074 4083 (Pubitemid 44338748)
26. A.L. Szymczak, C.J. Workman, Y. Wang, K.M. Vignali, S. Dilioglou, E.F. Vanin, and D.A. Vignali Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector Nat. Biotechnol. 22 2004 589 594 (Pubitemid 38585911)
27. M. Takemura, T. Mishima, Y. Wang, J. Kasahara, K. Fukunaga, K. Ohashi, and K. Mizuno Ca2+/calmodulin-dependent protein kinase IV-mediated LIM kinase activation is critical for calcium signal-induced neurite outgrowth J. Biol. Chem. 284 2009 28554 28562
28. S.J. Wakil, and L.A. Abu-Elheiga Fatty acid metabolism: target for metabolic syndrome J. Lipid Res. 50 Suppl 2009 S138 S143