Combination therapy with ampicillin and daptomycin for treatment of enterococcus faecalis endocarditis

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 11, 2012, Pages 6064-

  Sierra Hoffman, M ^a   Iznaola, O ^a   Goodwin, M ^b   Mohr, J ^c  

^a Beeville Medical Associates   (United States)

^b Optimer Pharmaceuticals   (United States)

^c CUBIST PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; CREATINE KINASE; DAPTOMYCIN; LEVOFLOXACIN;

AGED; BACTERIAL ENDOCARDITIS; BLOOD CULTURE; CASE REPORT; CELL DEATH; CHOLELITHIASIS; CHRONIC KIDNEY DISEASE; CONFUSION; ENTEROCOCCAL INFECTION; ENTEROCOCCUS FAECALIS; FEMALE; FEVER; GLOMERULUS FILTRATION RATE; HEMODIALYSIS PATIENT; HUMAN; HYPERTENSION; IN VITRO STUDY; LETTER; PRIORITY JOURNAL; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; VANCOMYCIN RESISTANT ENTEROCOCCUS;

AGED, 80 AND OVER; AMPICILLIN; ANTI-BACTERIAL AGENTS; DAPTOMYCIN; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; ENDOCARDITIS, BACTERIAL; ENTEROCOCCUS FAECALIS; FEMALE; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; MICROBIAL SENSITIVITY TESTS;

EID: 84868021561     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01760-12     Document Type: Letter

References (4)

1. Arias CA, et al. 2007. Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster. Clin. Infect. Dis. 45:1343-1346.
2. Entenza JM, Giddey M, Vouillamoz J, Moreillon P. 2010. In vitro prevention of the emergence of daptomycin resistance in Staphylococcus aureus and enterococci following combination with amoxicillin/clavulanic acid or ampicillin. Int. J. Antimicrob. Agents 35:451-456.
3. Murdoch DR, et al. 2009. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study. Arch. Intern. Med. 169:463-473.
4. Sakoulas G, et al. 2012. Ampicillin enhances daptomycin- and cationic host defense peptide-mediated killing of ampicillin- and vancomycinresistant Enterococcus faecium. Antimicrob. Agents Chemother. 56:838-844.