Toxicity mechanisms of amphotericin B and its neutralization by conjugation with arabinogalactan

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 11, 2012, Pages 5603-5611

  Kagan, Sarah ^a   Ickowicz, Diana ^b   Shmuel, Miriam ^b   Altschuler, Yoram ^b   Sionov, Edward ^a,d   Pitusi, Miriam ^a   Weiss, Aryeh ^c   Farber, Shimon ^b   Domb, Abraham J ^b   Polacheck, Itzhack ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ARABINOGALACTAN; CHEMOKINE RECEPTOR CXCR4; GREEN FLUORESCENT PROTEIN; MUSCARINIC M1 RECEPTOR; TRANSFERRIN RECEPTOR;

ANIMAL CELL; ARTICLE; CELL LINE; CELL MIGRATION; CONTROLLED STUDY; DRUG CONJUGATION; ENDOSOME; FUNGAL CELL; KIDNEY CELL; MAMMAL CELL; MYCOSIS; NONHUMAN; PH; PRIORITY JOURNAL;

AMPHOTERICIN B; ANIMALS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CHEMOKINES, CXC; DOGS; ENDOSOMES; GALACTANS; HUMANS; HYDROGEN-ION CONCENTRATION; KIDNEY; MADIN DARBY CANINE KIDNEY CELLS; MICROBIAL SENSITIVITY TESTS; PROTEIN TRANSPORT; RECEPTOR, MUSCARINIC M1; RECEPTORS, CXCR4; RECEPTORS, TRANSFERRIN; SPECIES SPECIFICITY; TRANSFERRIN; VERO CELLS;

EID: 84868018460     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00612-12     Document Type: Article

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