Galectin-3 expression in response to LPS, immunomodulatory drugs and exogenously added galectin-3 in monocyte-like THP-1 cells

In Vitro Cellular and Developmental Biology - Animal

Volumn 48, Issue 8, 2012, Pages 518-527

  Dabelic, Sanja ^a   Novak, Ruder ^a   Goreta, Sandra Supraha ^a   Dumic, Jerka ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

Cytokines; Galectin 3; Immunomodulatory drugs; LPS; Monocyte like THP 1 cells

Indexed keywords

ACETYLSALICYLIC ACID; CYTOKINE; DEXAMETHASONE; GALECTIN 3; IMMUNOLOGIC FACTOR; INDOMETACIN; LIPOPOLYSACCHARIDE; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL; ARTICLE; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LEUKEMIA CELL LINE; METABOLISM; MONOCYTE; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CYTOKINES; DEXAMETHASONE; GALECTIN 3; GENE EXPRESSION REGULATION; HUMANS; IMMUNOLOGIC FACTORS; INDOMETHACIN; JURKAT CELLS; LIPOPOLYSACCHARIDES; MONOCYTES; RATS;

EID: 84867988844     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11626-012-9540-x     Document Type: Article

References (47)

1. Al-Ansari S.; Zeebregts C. J.; Slart R. H.; Peppelenbosch M.; Tio R. A. Galectins in atherosclerotic disease. Trends Cardiovasc. Med. 19: 164-169; 2009.
2. Aubin J. E.; Gupta A. K.; Bhargava U.; Turksen K. Expression and regulation of galectin 3 in rat osteoblastic cells. J. Cell. Physiol. 169: 468-480; 1996. (Pubitemid 26426913)
3. Cortegano I.; Pozo V.; Cardaba B.; Arrieta I.; Gallardo S.; Rojo M.; Aceituno E.; Takai T.; Verbeek S.; Palomino P.; Liu F. T.; Lahoz C. Interaction between galectin-3 and FcgammaRII induces down-regulation of IL-5 gene: Implication of the promoter sequence IL-5REIII. Glycobiology 10: 237-242; 2000. (Pubitemid 30145195)
4. Dabelic S.; Flogel M.; Dumic J. Effects of aspirin and indomethacin on galectin-3. Croat. Chem. Acta 78: 433-440; 2005a. (Pubitemid 41525967)
5. Dabelic S.; Flogel M.; Dumic J. Hydrocortisone and dexamethasone affect galectin-3 expression. Period Biol. 107: 175-181; 2005b. (Pubitemid 40979103)
6. Dabelic S.; Supraha S.; Dumic J. Galectin-3 in macrophage-like cells exposed to immunomodulatory drugs. Biochim. Biophys. Acta 1760: 701-709; 2006.
7. Dagher S. F.; Wang J. L.; Patterson R. J. Identification of galectin-3 as a factor in pre-mRNA splicing. Proc. Natl. Acad. Sci. USA 92: 1213-1217; 1995.
8. Davicino R. C.; Elicabe R. J.; Di Genaro M. S.; Rabinovich G. A. Coupling pathogen recognition to innate immunity through glycan-dependent mechanisms. Int. Immunopharmacol. 11: 1457-1463; 2011.
9. Demetriou M.; Granovsky M.; Quaggin S.; Dennis J. W. Negative regulation of T-cell activation and autoimmunity by Mgat5 Nglycosylation. Nature 409: 733-739; 2001. (Pubitemid 32144520)
10. Dhirapong A.; Lleo A.; Leung P.; Gershwin M. E.; Liu F. T. The immunological potential of galectin-1 and -3. Autoimmun. Rev. 8: 360-363; 2009.
11. Diaz J. A.; Ramacciotti E.; Wakefield T. W. Do galectins play a role in venous thrombosis? a review. Thromb. Res. 125: 373-376; 2010.
12. Dumic J.; Dabelic S.; Flogel M. Galectin-3: An open-ended story. Biochim. Biophys. Acta 1760: 616-635; 2006. (Pubitemid 44382499)
13. Dumic J.; Lauc G.; Flogel M. Expression of galectin-3 in cells exposed to stress-roles of jun and NF-kappaB. Cell. Physiol. Biochem. 10: 149-158; 2000.
14. Elola M. T.; Wolfenstein-Todel C.; Troncoso M. F.; Vasta G. R.; Rabinovich G. A. Galectins: Matricellular glycan-binding proteins linking cell adhesion, migration, and survival. Cell. Mol. Life Sci. 64: 1679-1700; 2007. (Pubitemid 47036942)
15. Farnworth S. L.; Henderson N. C.; Mackinnon A. C.; Atkinson K. M.; Wilkinson T.; Dhaliwal K.; Hayashi K.; Simpson A. J.; Rossi A. G.; Haslett C.; Sethi T. Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function. Am. J. Pathol. 172: 395-405; 2008. (Pubitemid 351282027)
16. Filer A.; Bik M.; Parsonage G. N.; Fitton J.; Trebilcock E.; Howlett K.; Cook M.; Raza K.; Simmons D. L.; Thomas A. M.; Salmon M.; Scheel-Toellner D.; Lord J. M.; Rabinovich G. A.; Buckley C. D. Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways. Arthritis Rheum. 60: 1604-1614; 2009.
17. Fukumori T.; Takenaka Y.; Yoshii T.; Kim H. R.; Hogan V.; Inohara H.; Kagawa S.; Raz A. CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis. Cancer Res. 63: 8302-8311; 2003. (Pubitemid 37549482)
18. Jeng K. C.; Frigeri L. G.; Liu F. T. An endogenous lectin, galectin-3 (epsilon BP/Mac-2), potentiates IL-1 production by human monocytes. Immunol. Lett. 42: 113-116; 1994.
19. Jeon S. B.; Yoon H. J.; Chang C. Y.; Koh H. S.; Jeon S. H.; Park E. J. Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway. J. Immunol. 185: 7037-7046; 2010.
20. Jiang H. R.; Al Rasebi Z.; Mensah-Brown E.; Shahin A.; Xu D.; Goodyear C. S.; Fukada S. Y.; Liu F. T.; Liew F. Y.; Lukic M. L. Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. J. Immunol. 182: 1167-1173; 2009.
21. Karlsson A.; Christenson K.; Matlak M.; Bjorstad A.; Brown K. L.; Telemo E.; Salomonsson E.; Leffler H.; Bylund J. Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils. Glycobiology 19: 16-20; 2009.
22. Kim K.; Mayer E. P.; Nachtigal M. Galectin-3 expression in macrophages is signaled by Ras/MAP kinase pathway and up-regulated by modified lipoproteins. Biochim. Biophys. Acta 1641: 13-23; 2003. (Pubitemid 36638705)
23. Kuklinski S.; Vladimirova V.; Waha A.; Kamata H.; Pesheva P.; Probstmeier R. Expression of galectin-3 in neuronally differentiating PC12 cells is regulated both via Ras/MAPK-dependent and -independent signalling pathways. J. Neurochem. 87: 1112-1124; 2003. (Pubitemid 37485068)
24. Levi G.; Teichberg V. I. Isolation and physicochemical characterization of electrolectin, a beta-D-galactoside binding lectin from the electric organ of Electrophorus electricus. J. Biol. Chem. 256: 5735-5740; 1981.
25. Lippert E.; Falk W.; Bataille F.; Kaehne T.; Naumann M.; Goeke M.; Herfarth H.; Schoelmerich J.; Rogler G. Soluble galectin-3 is a strong, colonic epithelial-cell-derived, lamina propria fibroblaststimulating factor. Gut 56: 43-51; 2007. (Pubitemid 46044888)
26. Liu F. T.; Hsu D. K.; Zuberi R. I.; Kuwabara I.; Chi E. Y.; Henderson Jr. W. R. Expression and function of galectin-3, a betagalactoside-binding lectin, in human monocytes and macrophages. Am. J. Pathol. 147: 1016-1028; 1995.
27. Liu F. T.; Rabinovich G. A. Galectins: Regulators of acute and chronic inflammation. Ann. N. Y. Acad. Sci. 1183: 158-182; 2010.
28. Lowenberg M.; Stahn C.; Hommes D. W.; Buttgereit F. Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands. Steroids 73: 1025-1029; 2008.
29. MacKinnon A. C.; Farnworth S. L.; Hodkinson P. S.; Henderson N. C.; Atkinson K. M.; Leffler H.; Nilsson U. J.; Haslett C.; Forbes S. J.; Sethi T. Regulation of alternative macrophage activation by galectin-3. J. Immunol. 180: 2650-2658; 2008.
30. Maddox D. E.; Shibata S.; Goldstein I. J. Stimulated macrophages express a new glycoprotein receptor reactive with Griffonia simplicifolia I-B4 isolectin. Proc. Natl. Acad. Sci. USA 79: 166-170; 1982. (Pubitemid 12181507)
31. Maldonado C. A.; Sundblad V.; Salatino M.; Elia J.; Garcia L. N.; Leimgruber C.; Croci D. O.; Rabinovich G. A. Cell-type specific regulation of galectin-3 expression by glucocorticoids in lung Clara cells and macrophages. Histol. Histopathol. 26: 747-759; 2011.
32. Mengwasser J.; Liu F. T.; Sleeman J. P. Galectin-3 is strongly upregulated in nonapoptosing mammary epithelial cells during rat mammary gland involution. Glycobiology 12: 129-134; 2002. (Pubitemid 34428936)
33. Mey A.; Leffler H.; Hmama Z.; Normier G.; Revillard J. P. The animal lectin galectin-3 interacts with bacterial lipopolysaccharides via two independent sites. J. Immunol. 156: 1572-1577; 1996. (Pubitemid 26065869)
34. Nakahara S.; Raz A. Regulation of cancer-related gene expression by galectin-3 and the molecular mechanism of its nuclear import pathway. Cancer Metastasis Rev. 26: 605-610; 2007. (Pubitemid 350115124)
35. Nangia-Makker P.; Nakahara S.; Hogan V.; Raz A. Galectin-3 in apoptosis, a novel therapeutic target. J. Bioenerg. Biomembr. 39: 79-84; 2007. (Pubitemid 46877176)
36. Nieminen J.; St-Pierre C.; Sato S. Galectin-3 interacts with naive and primed neutrophils, inducing innate immune responses. J. Leukoc. Biol. 78: 1127-1135; 2005. (Pubitemid 41572476)
37. Nishi Y.; Sano H.; Kawashima T.; Okada T.; Kuroda T.; Kikkawa K.; Kawashima S.; Tanabe M.; Goto T.; Matsuzawa Y.; Matsumura R.; Tomioka H.; Liu F. T.; Shirai K. Role of galectin-3 in human pulmonary fibrosis. Allergol. Int. 56: 57-65; 2007. (Pubitemid 46449664)
38. Norling L. V.; Perretti M.; Cooper D. Endogenous galectins and the control of the host inflammatory response. J. Endocrinol. 201: 169-184; 2009.
39. Novak R.; Dabelic S.; Dumic J. Galectin-1 and galectin-3 expression profiles in classically and alternatively activated human macrophages. Biochim. Biophys. Acta. 1820(9): 1383-90; 2012.
40. Oberg C. T.; Leffler H.; Nilsson U. J. Inhibition of galectins with small molecules. Chimia (Aarau) 65: 18-23; 2011.
41. Sano H.; Hsu D. K.; Yu L.; Apgar J. R.; Kuwabara I.; Yamanaka T.; Hirashima M.; Liu F. T. Human galectin-3 is a novel chemoattractant for monocytes and macrophages. J. Immunol. 165: 2156-2164; 2000. (Pubitemid 30643165)
42. Sarter K.; Andre S.; Kaltner H.; Lensch M.; Schulze C.; Urbonaviciute V.; Schett G.; Herrmann M.; Gabius H. J. Detection and chromatographic removal of lipopolysaccharide in preparations of multifunctional galectins. Biochem. Biophys. Res. Commun. 379: 155-159; 2009.
43. Song S.; Mazurek N.; Liu C.; Sun Y.; Ding Q. Q.; Liu K.; Hung M. C.; Bresalier R. S. Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity. Cancer Res. 69: 1343-1349; 2009.
44. Sundblad V.; Croci D. O.; Rabinovich G. A. Regulated expression of galectin-3, a multifunctional glycan-binding protein, in haematopoietic and non-haematopoietic tissues. Histol. Histopathol. 26: 247-265; 2011.
45. Toscano M. A.; Bianco G. A.; Ilarregui J. M.; Croci D. O.; Correale J.; Hernandez J. D.; Zwirner N. W.; Poirier F.; Riley E. M.; Baum L. G.; Rabinovich G. A. Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death. Nat. Immunol. 8: 825-834; 2007. (Pubitemid 47099035)
46. Ueland T.; Aukrust P.; Broch K.; Aakhus S.; Skardal R.; Muntendam P.; Gullestad L. Galectin-3 in heart failure: High levels are associated with all-cause mortality. Int. J. Cardiol. 150: 361-364; 2011.
47. Yang R. Y.; Rabinovich G. A.; Liu F. T. Galectins: Structure, function and therapeutic potential. Expert Rev. Mol. Med. 10: E17; 2008.