MiRNA regulates noncoding RNA: A noncanonical function model

Trends in Biochemical Sciences

Volumn 37, Issue 11, 2012, Pages 457-459

  Chen, Xi ^a   Liang, Hongwei ^a   Zhang, Chen Yu ^a   Zen, Ke ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Argonaute; Exportin; Importin; MiRNA; Noncoding RNA; Nucleus

Indexed keywords

ARGONAUTE 1 PROTEIN; ARGONAUTE PROTEIN; EXPORTIN 1; KARYOPHERIN; MICRORNA; MICRORNA 15A; MICRORNA 709; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

ALG1 GENE; BIOGENESIS; CELL NUCLEUS; CYTOPLASM; GENE; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE REPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROCESSING; RNA ANALYSIS; RNA CLEAVAGE; RNA DEGRADATION; RNA TRANSPORT; SHORT SURVEY;

ANIMALS; BIOLOGICAL TRANSPORT; CELL NUCLEUS; HUMANS; MICRORNAS; MODELS, BIOLOGICAL; RNA STABILITY; RNA, LONG UNTRANSLATED; RNA, NUCLEAR; RNA, UNTRANSLATED;

EID: 84867904918     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tibs.2012.08.005     Document Type: Short Survey

References (10)

1. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
2. Meister G., et al. Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell 2004, 15:185-197.
3. Politz J.C.R., et al. MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:18957-18962.
4. Hwang H.W., et al. A hexanucleotide element directs microRNA nuclear import. Science 2007, 315:97-100.
5. Robb G.B., et al. Specific and potent RNAi in the nucleus of human cells. Nat. Struct. Mol. Biol. 2005, 12:133-137.
6. Castanotto D., et al. CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:21655-21659.
7. Zisoulis D.G., et al. Autoregulation of microRNA biogenesis by let-7 and Argonaute. Nature 2012, 486:541-544.
8. Weinmann L., et al. Importin 8 is a gene silencing factor that targets Argonaute proteins to distinct mRNAs. Cell 2009, 136:496-507.
9. Tang R., et al. Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system. Cell Res. 2012, 22:504-515.
10. Hansen T.B., et al. miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA. EMBO J. 2011, 30:4414-4422.