-
1
-
-
33645728523
-
Neurodegenerative diseases: New concepts of pathogenesis and their therapeutic implications
-
Skovronsky DM, Lee VM, Trojanowski JQ (2006) Neurodegenerative diseases: New concepts of pathogenesis and their therapeutic implications. Annu Rev Pathol 1: 151-170.
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 151-170
-
-
Skovronsky, D.M.1
Lee, V.M.2
Trojanowski, J.Q.3
-
2
-
-
84867908726
-
O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases
-
Wang P, et al. (2012) O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases. Proc Natl Acad Sci USA 109:17669-17674.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 17669-17674
-
-
Wang, P.1
-
3
-
-
77949769388
-
O-linked beta- N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress
-
Butkinaree C, Park K, Hart GW (2010) O-linked beta- N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress. Biochim Biophys Acta 1800(2):96-106.
-
(2010)
Biochim Biophys Acta
, vol.1800
, Issue.2
, pp. 96-106
-
-
Butkinaree, C.1
Park, K.2
Hart, G.W.3
-
4
-
-
77955273167
-
O-GlcNAc cycling: Emerging roles in development and epigenetics
-
Love DC, Krause MW, Hanover JA (2010) O-GlcNAc cycling: Emerging roles in development and epigenetics. Semin Cell Dev Biol 21(6):646-654.
-
(2010)
Semin Cell Dev Biol
, vol.21
, Issue.6
, pp. 646-654
-
-
Love, D.C.1
Krause, M.W.2
Hanover, J.A.3
-
5
-
-
84865191053
-
Developmental Regulation of Protein O-GlcNAcylation, O-GlcNAc Transferase, and O-GlcNAcase in Mammalian Brain
-
Liu Y, et al. (2012) Developmental Regulation of Protein O-GlcNAcylation, O-GlcNAc Transferase, and O-GlcNAcase in Mammalian Brain. PLoS ONE 7(8):e43724.
-
(2012)
PLoS ONE
, vol.7
, Issue.8
-
-
Liu, Y.1
-
6
-
-
0034705030
-
The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny
-
DOI 10.1073/pnas.100471497
-
Shafi R, et al. (2000) The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny. Proc Natl Acad Sci USA 97(11):5735-5739. (Pubitemid 30367467)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.11
, pp. 5735-5739
-
-
Shafi, R.1
Iyer, S.P.N.2
Ellies, L.G.3
O'Donnell, N.4
Marek, K.W.5
Chui, D.6
Hart, G.W.7
Marth, J.D.8
-
7
-
-
65649145706
-
O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development
-
Webster DM, et al. (2009) O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development. BMC Dev Biol 9:28.
-
(2009)
BMC Dev Biol
, vol.9
, pp. 28
-
-
Webster, D.M.1
-
8
-
-
47649114560
-
A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo
-
Yuzwa SA, et al. (2008) A potent mechanism-inspired O-GlcNAcase inhibitor that blocks phosphorylation of tau in vivo. Nat Chem Biol 4(8):483-490.
-
(2008)
Nat Chem Biol
, vol.4
, Issue.8
, pp. 483-490
-
-
Yuzwa, S.A.1
-
9
-
-
67650072530
-
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease
-
Liu F, et al. (2009) Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. Brain 132(Pt 7):1820-1832.
-
(2009)
Brain
, vol.132
, Issue.PART 7
, pp. 1820-1832
-
-
Liu, F.1
-
10
-
-
84858664547
-
Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation
-
Yuzwa SA, et al. (2012) Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nat Chem Biol 8(4):393-399.
-
(2012)
Nat Chem Biol
, vol.8
, Issue.4
, pp. 393-399
-
-
Yuzwa, S.A.1
-
11
-
-
2542446200
-
Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high c-GlcNAc metabolism
-
DOI 10.1111/j.1471-4159.2004.02389.x
-
Liu K, et al. (2004) Accumulation of protein O-GlcNAc modi fication inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism. J Neurochem 89 (4):1044-1055. (Pubitemid 38684749)
-
(2004)
Journal of Neurochemistry
, vol.89
, Issue.4
, pp. 1044-1055
-
-
Liu, K.1
Paterson, A.J.2
Zhang, F.3
McAndrew, J.4
Fukuchi, K.-I.5
Wyss, J.M.6
Peng, L.7
Hu, Y.8
Kudlow, J.E.9
-
12
-
-
84860811239
-
Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets
-
Alfaro JF, et al. (2012) Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets. Proc Natl Acad Sci USA 109(19):7280-7285.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.19
, pp. 7280-7285
-
-
Alfaro, J.F.1
-
13
-
-
3242739968
-
O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
-
DOI 10.1073/pnas.0400348101
-
Liu F, Iqbal K, Grundke-Iqbal I, Hart GW, Gong CX (2004) O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease. Proc Natl Acad Sci USA 101(29):10804-10809. (Pubitemid 38955823)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.29
, pp. 10804-10809
-
-
Liu, F.1
Iqbal, K.2
Grundke-Iqbal, I.3
Hart, G.W.4
Gong, C.-X.5
-
14
-
-
77956961240
-
Elevation of Global O-GlcNAc in rodents using a selective O-GlcNAcase inhibitor does not cause insulin resistance or perturb glucohomeostasis
-
Macauley MS, Shan X, Yuzwa SA, Gloster TM, Vocadlo DJ (2010) Elevation of Global O-GlcNAc in rodents using a selective O-GlcNAcase inhibitor does not cause insulin resistance or perturb glucohomeostasis. Chem Biol 17(9):949- 958.
-
(2010)
Chem Biol
, vol.17
, Issue.9
, pp. 949-958
-
-
Macauley, M.S.1
Shan, X.2
Yuzwa, S.A.3
Gloster, T.M.4
Vocadlo, D.J.5
-
15
-
-
3042613480
-
O-GlcNAc a sensor of cellular state: The role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress
-
DOI 10.1016/j.bbagen.2004.03.016, PII S0304416504001023
-
Zachara NE, Hart GW (2004) O-GlcNAc a sensor of cellular state: The role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress. Biochim Biophys Acta 1673 (1-2):13-28. (Pubitemid 38844791)
-
(2004)
Biochimica et Biophysica Acta - General Subjects
, vol.1673
, Issue.1-2
, pp. 13-28
-
-
Zachara, N.E.1
Hart, G.W.2
-
16
-
-
23844481789
-
A Caenorhabditis elegans model of insulin resistance: Altered macronutrient storage and dauer formation in an OGT-1 knockout
-
Hanover JA, et al. (2005) A Caenorhabditis elegans model of insulin resistance: altered macronutrient storage and dauer formation in an OGT-1 knockout. Proc Natl Acad Sci USA 102(32):11266- 11271.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.32
, pp. 11266-11271
-
-
Hanover, J.A.1
-
17
-
-
33646008860
-
Concurrent alterations of O-GlcNAcylation and phosphorylation of tau in mouse brains during fasting
-
Li X, Lu F, Wang JZ, Gong CX (2006) Concurrent alterations of O-GlcNAcylation and phosphorylation of tau in mouse brains during fasting. Eur J Neurosci 23(8):2078-2086.
-
(2006)
Eur J Neurosci
, vol.23
, Issue.8
, pp. 2078-2086
-
-
Li, X.1
Lu, F.2
Wang, J.Z.3
Gong, C.X.4
-
18
-
-
77952117808
-
Targeting tau protein in Alzheimer ' s disease
-
Gong CX, Grundke-Iqbal I, Iqbal K (2010) Targeting tau protein in Alzheimer ' s disease. Drugs Aging 27 (5):351-365.
-
(2010)
Drugs Aging
, vol.27
, Issue.5
, pp. 351-365
-
-
Gong, C.X.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
19
-
-
0028988780
-
Beta-amyloid precursor protein is modified with O-linked N-acetylglucosamine
-
Griffith LS, Mathes M, Schmitz B (1995) Beta-amyloid precursor protein is modified with O-linked N-acetylglucosamine. J Neurosci Res 41(2):270-278.
-
(1995)
J Neurosci Res
, vol.41
, Issue.2
, pp. 270-278
-
-
Griffith, L.S.1
Mathes, M.2
Schmitz, B.3
-
20
-
-
78751620383
-
O-GlcNAcylation increases non-amyloidogenic processing of the amyloid-β precursor protein (APP)
-
Jacobsen KT, Iverfeldt K (2011) O-GlcNAcylation increases non-amyloidogenic processing of the amyloid-β precursor protein (APP). Biochem Biophys Res Commun 404(3): 882-886.
-
(2011)
Biochem Biophys Res Commun
, vol.404
, Issue.3
, pp. 882-886
-
-
Jacobsen, K.T.1
Iverfeldt, K.2
-
21
-
-
0034704198
-
Evidence for genetic linkage Alzheimer's disease to chromosome 10q
-
DOI 10.1126/science.290.5500.2302
-
Bertram L, et al. (2000) Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science 290 (5500):2302-2303. (Pubitemid 32041570)
-
(2000)
Science
, vol.290
, Issue.5500
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
Yhu, S.7
McInnis, M.G.8
Go, R.C.P.9
Vekrellis, K.10
Selkoe, D.J.11
Saunders, A.J.12
Tanzi, R.E.13
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