Both BMI and waist circumference are associated with coronary vasoreactivity in overweight and obese men

Obesity Facts

Volumn 5, Issue 5, 2012, Pages 693-699

  Sundell, Jan ^a   Raitakari, Olli T ^a   Viikari, Jorma ^a   Kantola, Ilkka ^a   Nuutila, Pirjo ^a   Knuuti, Juhani ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Adenosine; Myocardial blood flow; Obesity; Positron emission tomography

Indexed keywords

ADENOSINE; HEMOGLOBIN A1C; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXYGEN 15; WATER;

ADULT; AGE; ARTICLE; BLOOD VESSEL REACTIVITY; BODY MASS; CLINICAL ARTICLE; CORONARY BLOOD VESSEL; HEART MUSCLE BLOOD FLOW; HUMAN; ISOTOPE LABELING; MALE; OBESITY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE; WAIST HIP RATIO;

ADENOSINE; ADULT; BODY MASS INDEX; CORONARY CIRCULATION; CORONARY DISEASE; CORONARY VESSELS; HUMANS; MALE; MIDDLE AGED; OBESITY; OVERWEIGHT; WAIST CIRCUMFERENCE; WAIST-HIP RATIO; YOUNG ADULT;

EID: 84867895463     PISSN: 16624025     EISSN: 16624033     Source Type: Journal    
DOI: 10.1159/000343711     Document Type: Article

References (27)

1. Eckel RH, Krauss RM: American Heart Association call to action: obesity as a major risk factor for coronary heart disease. AHA Nutrition Committee. Circulation 1998; 97: 2099-2100. (Pubitemid 28262114)
2. Van Itallie TB: Health implications of overweight and obesity in the United States. Ann Intern Med 1985; 103: 983-988. (Pubitemid 16211916)
3. Despres JP, Lemieux I, Bergeron J, Pibarot P, Mathieu P, Larose E, Rodés-Cabau J, Bertrand OF, Poirier P: Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol 2008; 28: 1039-1049.
4. Canoy D: Coronary heart disease and body fat distribution. Curr Atheroscler Rep 2010; 12: 125-133.
5. The Emerging Risk Factors Collaboration: Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet 2011; 377: 1085-1095.
6. McGill HC Jr, McMahan CA, Herderick EE, Zieske AW, Malcom GT, Tracy RE, Strong JP: Obesity accelerates the progression of coronary atherosclerosis in young men. Circulation 2002; 105: 2712-2718. (Pubitemid 34615140)
7. Pitkänen OP, Raitakari OT, Rönnemaa T, Niinikoski H, Nuutila P, Iida H, Viikari JS, Knuuti J: Influence of cardiovascular risk status on coronary flow reserve in healthy young men. Am J Cardiol 1997; 79: 1690-1692. (Pubitemid 27339486)
8. Uren NG, Melin JA, De Bruyne B, Wijns W, Baudhuin T, Camici PG: Relation between myocardial blood flow and the severity of coronary artery stenosis. N Engl J Med 1994; 330: 1782-1788.
9. Crouzel C, Clark J, Brihaye C, Långström B, Lemaire C, Meyer G, Nebeling B, Stone-Elander S: Radiochemistry automation for PET; in Stöckling G, Pike V (eds): Radiopharmaceuticals for Positron Emission Tomography. Dordrecht, Kluwer Academic Publishers, 1993, pp 45-90.
10. Laine H, Raitakari OT, Niinikoski H, Pitkänen OP, Iida H, Viikari J, Nuutila P, Knuuti J: Early impairment of coronary flow reserve in young men with borderline hypertension. J Am Coll Cardiol 1998; 32: 147-153. (Pubitemid 28351056)
11. Iida H, Takahashi A, Tamura Y, Ono Y, Lammertsma AA: Myocardial blood flow: comparison of oxygen-15-water bolus injection, slow infusion and oxygen-15-carbon dioxide slow inhalation. J Nucl Med 1995; 36: 78-85.
12. Iida H, Rhodes CG, de Silva R, Araujo LI, Bloomfield PM, Lammertsma AA, Jones T: Use of the left ventricular time-activity curve as a noninvasive input function in dynamic oxygen-15-water positron emission tomography. J Nucl Med 1992; 33: 1669-1677.
13. Friedewald WT, Levy RI, Fredrickson DS: Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972; 18: 499-502.
14. Ziccardi P, Nappo F, Giugliano G, Esposito K, Marfella R, Cioffi M, D'Andrea F, Molinari AM, Giugliano D: Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation 2002; 105: 804-809. (Pubitemid 34174919)
15. Steinberg HO, Chaker H, Leaming R, Johnson A, Brechtel G, Baron AD: Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996; 97: 2601-2610.
16. Madar Z, Zierath J, Nolte L, Thorne A, Voet h, Wallberg-Henriksson H: Human skeletal muscle nitric oxide synthase-characterization of its activity in obese subjects. Diabetes 1997; 46: 24A.
17. Al Suwaidi J, Higano ST, Holmes DR Jr, Lennon R, Lerman A: Obesity is independently associated with coronary endothelial dysfunction in patients with normal or mildly diseased coronary arteries. J Am Coll Cardiol 2001; 37: 1523-1528.
18. Sundell J, Laine H, Luotolahti M, Kalliokoski K, Raitakari O, Nuutila P, Knuuti J: Obesity affects myocardial vasoreactivity and coronary flow response to insulin. Obes Res 2002; 10: 617-624. (Pubitemid 135688260)
19. Katzel LI, Sorkin KD, Colman E, Goldberg AP, Busby-Whitehead MJ, Lakatta LE, Becker LC, Lakatta EG, Fleg JL: Risk factors for exercise-induced silent myocardial ischemia in healthy volunteers. Am J Cardiol 1994; 74: 869-874. (Pubitemid 24340307)
20. Lakka TA, Lakka HM, Salonen R, Kaplan GA, Salonen JT: Abdominal obesity is associated with accelerated progression of carotid atherosclerosis in men. Atherosclerosis 2001; 154: 497-504. (Pubitemid 32146625)
21. Schachinger V, Britten MB, Zeiher AM: Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000; 101: 1899-1906. (Pubitemid 30225269)
22. Vita JA, Treasure CB, Nabel EG, McLenachan JM, Fish RD, Yeung AC, Vekshtein VI, Selwyn AP, Ganz P: Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation 1990; 81: 491-497. (Pubitemid 20055957)
23. Nitzsche EU, Choi Y, Czernin J, Hoh CK, Huang SC, Schelbert HR: Noninvasive quantification of myocardial blood flow in humans. A direct comparison of the [13N]ammonia and the [15O]water techniques. Circulation 1996; 93: 2000-2006.
24. Mayhan WG: Endothelium-dependent responses of cerebral arterioles to adenosine 5-diphosphate. J Vasc Res 1992; 29: 353-358.
25. Buus NH, Bottcher M, Hermansen F, Sander M, Nielsen TT, Mulvany MJ: Influence of nitric oxide synthase and adrenergic inhibition on adenosine-induced myocardial hyperemia. Circulation 2001; 104: 2305-2310. (Pubitemid 33049513)
26. Wilson RF, Wyche K, Christensen BV, Zimmer S, Laxson DD: Effects of adenosine on human coronary arterial circulation. Circulation 1990; 82: 1595-1606. (Pubitemid 20367962)
27. Opie LH: The Heart, ed. 3. Philadelphia, Lippincott-Raven Publishers, 1998.