The nuclear factor-kB functional promoter polymorphism is associated with endometriosis and infertility

Human Immunology

Volumn 73, Issue 11, 2012, Pages 1190-1193

  Bianco, Bianca ^a   Lerner, Tatiana G ^a   Trevisan, Camila Martins ^a   Cavalcanti, Viviane ^a   Christofolini, Denise M ^a   Barbosa, Caio P ^a  

^a FACULDADE DE MEDICINA DO ABC   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOMETRIOSIS; FEMALE; FEMALE INFERTILITY; GENE DELETION; GENE INSERTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HUMAN; HYPOTHESIS; IDIOPATHIC DISEASE; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADULT; ALLELES; ENDOMETRIOSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INFERTILITY, FEMALE; NF-KAPPA B P50 SUBUNIT; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC;

EID: 84867888303     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2012.08.008     Document Type: Article

References (38)

1. Barbosa C.P., Souza A.M., Bianco B., Christofolini D., Mafra F.A., Lima G.R. Frequency of endometriotic lesions in peritoneum samples from asymptomatic fertile women and correlation with CA125 values. Sao Paulo Med J 2009, 127:342-345.
2. Barbosa C.P., de Souza A.M., Bianco B., Christofolini D., Mafra F.A., Lima G.R. OC-125 immunostaining in endometriotic lesion samples. Arch Gynecol Obstet 2010, 281:43-47.
3. Bianco B., Teles J.S., Lerner T.G., Vilarino F.L., Christofolini D.M., Barbosa C.P. Association of FCRL3 -169T/C polymorphism with endometriosis and identification of a protective haplotype against the development of the disease in Brazilian population. Hum Immunol 2011, 72:774-778.
4. André G.M., Barbosa C.P., Teles J.S., Vilarino F.L., Christofolini D.M., Bianco B. Analysis of FOXP3 polymorphisms in infertile women with and without endometriosis. Fertil Steril 2011, 95:2223-2227.
5. Gomes F.M., Bianco B., Teles J.S., Christofolini D.M., de Souza A.M., Guedes A.D., et al. PTPN22 C1858T polymorphism in women with endometriosis. Am J Reprod Immunol 2010, 63:227-232.
6. Bianco B., André G.M., Vilarino F.L., Peluso C., Mafra F.A., Christofolini D.M., et al. The possible role of genetic variants in autoimmune-related genes in the development of endometriosis. Hum Immunol 2012, 73(3):306-315.
7. Dmowski W.P., Gebel H.M., Braun D.P. The role of cell-mediated immunity in pathogenesis of endometriosis. Acta Obstet Gynecol Scand 1994, 159:7-14.
8. Viatour P., Merville M.P., Bours V., Chariot A. Phosphorylation of NF-kB and IkB proteins: implications in cancer and inflammation. Trends Biochem Sci 2005, 30:43-52.
9. Perkins N.D. Integrating cell-signalling pathways with NF-kB and IKK function. Nat Rev Mol Cell Biol 2007, 8:49-62.
10. Zhou B., Rao L., Peng Y., Wang Y., Qie M., Zhang Z., et al. A functional promoter polymorphism in NFKB1 increases susceptibility to endometriosis. DNA Cell Biol 2010, 29(5):235-239.
11. Chen F., Castranova V., Shi X., Demers L.M. New insights into the role of nuclear factor-kappaB, a ubiquitous transcription factor in the initiation of diseases. Clin Chem 1999, 45:7-17.
12. Karban A.S., Okazaki T., Panhuysen C.I., Gallegos T., Potter J.J., Bailey-Wilson J.E., et al. Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Hum Mol Genet 2004, 13:35-45.
13. Li H., Gao L., Shen Z., Li C.Y., Li K., Li M., et al. Association study of NFKB1 and SUMO4 polymorphisms in Chinese patients with psoriasis vulgaris. Arch Dermatol Res 2008, 300:425-433.
14. Lin S.C., Liu C.J., Yeh W.I., Lui M.T., Chang K.W., Chang C.S. Functional polymorphism in NFKB1 promoter is related to the risks of oral squamous cell carcinoma occurring on older male areca (betel) chewers. Cancer Lett 2006, 243:47-54.
15. Zhou B., Rao L., Li Y., Gao L., Wang Y., Chen Y., et al. A functional insertion/deletion polymorphism in the promoter region of NFKB1 gene increases susceptibility for nasopharyngeal carcinoma. Cancer Lett 2009, 275:72-76.
16. Zhou B., Rao L., Peng Y., Wang Y., Li Y., Gao L., et al. Functional polymorphism of the NFKB1 gene promoter is related to the risk of dilated cardiomyopathy. BMC Med Genet 2009, 10:1-5.
17. American society for reproductive medicine classification of endometriosis. Fertil Steril 1997, 67:817-821.
18. Lahiri D.K., Nurnberger J.I. A rapid non-enzymatic method for preparation of HMW DNA from blood for RFLP studies. Nuclei Acids Res 1991, 19:5444.
19. Tuncay S.S., Okyay P., Bardakci F. Identification of NF-kB1 and NF-jBIA polymorphisms using PCR-RFLP assay in a turkish population. Biochem Genet 2010, 48:104-112.
20. Purcell S., Cherny S.S., Sham P.C. Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003, 19:149-150.
21. Koninckx P.R. Is mild endometriosis a condition occurring intermittently in all women?. Hum Reprod 1994, 9:2202-2205.
22. Vercellini P., Trespidi L., Panazza S., Bramante T., Mauro F., Crosignani P.G. Laparoscopic uterine biopsy for diagnosing diffuse adenomyosis. J Reprod Med 1996, 41:220-224.
23. Nisolle M., Nervo P. Physiopathology and therapeutic management of stage I and II endometriosis. J Gynecol Obstet Biol Reprod 2003, 32:S11-S14.
24. Naugler W.E., Karin M. NF-kappaB and cancer-identifying targets and mechanisms. Curr Opin Genet Dev 2008, 18(1):19-26.
25. White K.L., Vierkant R.A., Phelan C.M., Fridley B.L., Anderson S., Knutson K.L., et al. Polymorphisms in NF-kappaB inhibitors and risk of epithelial ovarian cancer. BMC Cancer. 2009, 6(9):170.
26. Starzinski-Powitz A., Handrow-Metzmacher H., Kotzian S. The putative role of cell adhesion molecules in endometriosis: can we learn from tumour metastasis?. Mol Med Today 1999, 5:304-309.
27. González-Ramos R., Donnez J., Defrère S., Leclercq I., Squifflet J., Lousse J.C., et al. Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis. Mol Hum Reprod 2007, 13(7):503-509.
28. Guo S.W. Nuclear factor-kappab (NF-kappaB): an unsuspected major culprit in the pathogenesis of endometriosis that is still at large?. Gynecol Obstet Invest 2007, 63:71-97.
29. González-Ramos R., Van Langendonckt A., Defrère S., Lousse J.C., Colette S., Devoto L., et al. Involvement of the nuclear factor-κB pathway in the pathogenesis of endometriosis. Fertil Steril 2010, 94(6):1985-1994.
30. Hastings J.M., Jackson K.S., Mavrogianis P.A., Fazleabas A.T. The estrogen early response gene FOS is altered in a baboon model of endometriosis. Biol Reprod 2006, 75(2):176-182.
31. González-Ramos R., Rocco J., Rojas C., Sovino H., Poch A., Kohen P., et al. Physiologic activation of nuclear factor kappa-B in the endometrium during the menstrual cycle is altered in endometriosis patients. Fertil Steril 2012, 97(3):645-651.
32. Braun D.P., Dmowski W.P. Endometriosis: abnormal endometrium and dysfunctional immune response. Curr Opin Obstet Gynecol 1998, 10:365-369.
33. Matarese G., De Placido G., Nikas Y., Alviggi C. Pathogenesis of endometriosis: natural immunity dysfunction or autoimmune disease?. Trends Mol Med 2003, 9:223-228.
34. Harnish D.C. Estrogen receptor ligands in the control of pathogenic inflammation. Curr Opin Investig Drugs 2006, 7:997-1001.
35. Feldman I., Feldman G.M., Mobarak C., Dunkelberg J.C., Leslie K.K. Identification of proteins within the nuclear factor-kappa B transcriptional complex including estrogen receptor-alpha. Am J Obstet Gynecol 2007, 196:394e1-394e311.
36. Quaedackers M.E., van den Brink C.E., van der Saag P.T., Tertoolen L.G. Direct interaction between estrogen receptor alpha and NF-kappaB in the nucleus of living cells. Mol Cell Endocrinol 2007, 273:42-50.
37. Evans M.J., Eckert A., Lai K., Adelman S.J., Harnish D.C. Reciprocal antagonism between estrogen receptor and NF-kappaB activity in vivo. Circ Res 2001, 89:823-830.
38. King A.E., Collins F., Klonisch T., Sallenave J.M., Critchley H.O., Saunders P.T. An additive interaction between the NFkappaB and estrogen receptor signalling pathways in human endometrial epithelial cells. Hum Reprod 2010, 25(2):510-518.