Hepatocyte hopping of oatp1b substrates contributes to efficient hepatic detoxification

Clinical Pharmacology and Therapeutics

Volumn 92, Issue 5, 2012, Pages 559-562

  Iusuf, D ^a   Van De Steeg, E ^a   Schinkel, A H ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN GLUCURONIDE; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 1 B1; ORGANIC ANION TRANSPORTER 1 B3; UNCLASSIFIED DRUG;

ARTICLE; DETOXIFICATION; GENETIC DISORDER; GENETIC VARIABILITY; HUMAN; LIVER CELL; LIVER DETOXIFICATION; MALE; MOUSE; NONHUMAN; PHARMACOGENETICS; PRIORITY JOURNAL; PROTEIN FUNCTION; ROTOR SYNDROME;

ANIMALS; ANIONS; BIOLOGICAL TRANSPORT; CATIONS; HEPATOCYTES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIVER; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; PHARMACEUTICAL PREPARATIONS;

EID: 84867887941     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.143     Document Type: Article

References (5)

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3. Iusuf, D., van de Steeg, E. & Schinkel, A.H. Functions of OATP1A and 1B transporters in vivo: insights from mouse models. Trends Pharmacol. Sci. 33, 100-108 (2012).
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