Kidney transplantation after desensitization in sensitized patients: A Korean National Audit

International Urology and Nephrology

Volumn 44, Issue 5, 2012, Pages 1549-1557

  Huh, Kyu Ha ^a   Kim, Beom Seok ^a   Yang, Jaeseok ^b,c   Ahn, Jeongmyung ^d   Kim, Myung Gyu ^b   Park, Jae Berm ^e   Kim, Jong Man ^d   Chung, Byung Ha ^g   Kim, Joong Kyung ^h   Kong, Jin Min ^f  

^a Yonsei University   (South Korea)

^b Seoul National University Hospital   (South Korea)

^c Seoul National University   (South Korea)

^d Maryknoll Hospital   (South Korea)

^e University of Ulsan College of Medicine   (South Korea)

^f Sungkyunkwan University   (South Korea)

^g The Catholic University of Korea   (South Korea)

^h Bong Seng Hospital   (South Korea)

Author keywords

Immunologic desensitization; Kidney transplantation; Rejection

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN ANTIBODY; MYCOPHENOLIC ACID; PREDNISOLONE; RITUXIMAB; TACROLIMUS;

ACUTE GRAFT REJECTION; ADULT; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; BK VIRUS INFECTION; BLOOD GROUP TYPING; CHICKENPOX; CLINICAL PROTOCOL; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DESENSITIZATION; DISEASE FREE SURVIVAL; DRUG PULSE THERAPY; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; GRAFT FAILURE; GRAFT SURVIVAL; HERPES ZOSTER; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DISEASE; KIDNEY FAILURE; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; KOREA; LIVING DONOR; LOW DRUG DOSE; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; PLASMAPHERESIS; PNEUMONIA; POPULATION RESEARCH; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE INFECTION; PREOPERATIVE CARE; RETRANSPLANTATION; RETROSPECTIVE STUDY; SURVIVAL RATE; TREATMENT INDICATION; TREATMENT OUTCOME;

ADULT; ANTIBODIES; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; DESENSITIZATION, IMMUNOLOGIC; DISEASE-FREE SURVIVAL; FEMALE; GLOMERULAR FILTRATION RATE; GRAFT REJECTION; GRAFT SURVIVAL; HISTOCOMPATIBILITY; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOLOGIC FACTORS; KAPLAN-MEIER ESTIMATE; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PLASMAPHERESIS; REPUBLIC OF KOREA; RETROSPECTIVE STUDIES;

EID: 84867867605     PISSN: 03011623     EISSN: 15732584     Source Type: Journal    
DOI: 10.1007/s11255-012-0169-1     Document Type: Article

References (24)

1. Vo AA, Lukovsky M, Toyoda M, Wang J, Reinsmoen NL, Lai CH et al (2008) Rituximab and intravenous immune globulin for desensitization during renal transplantation. N Engl J Med 359(3):242-251
2. Joo SY, Ha J, Kim SJ, Park MH (2009) Analysis of panel reactive antibody in patients awaiting renal transplantation. J Korean Soc Transplant 23(1):28-35
3. Marfo K, Lu A, Ling M, Akalin E (2011) Desensitization protocols and their outcome. Clin J Am Soc Nephrol 6(4):922-936
4. Montgomery RA, Zachary AA (2004) Transplanting patients with a positive donor-specific crossmatch: a single center's perspective. Pediatr Transplant 8(6):535-542
5. Stegall MD, Gloor J, Winters JL, Moore SB, Degoey S (2006) A comparison of plasmapheresis versus high-dose IVIG desensitization in renal allograft recipients with high levels of donor specific alloantibody. Am J Transplant 6(2):346-351
6. Vo AA, Wechsler EA, Wang J, Peng A, Toyoda M, Lukovsky M et al (2008) Analysis of subcutaneous (SQ) alemtuzumab induction therapy in highly sensitized patients desensitized with IVIG and rituximab. Am J Transplant 8(1):144-149
7. Jordan SC, Vo A, Bunnapradist S, Toyoda M, Peng A, Puliyanda D et al (2003) Intravenous immune globulin treatment inhibits crossmatch positivity and allows for successful transplantation of incompatible organs in living-donor and cadaver recipients. Transplantation 76(4):631-636
8. West-Thielke P, Herren H, Thielke J, Oberholzer J, Sankary H, Raofi V et al (2008) Results of positive cross-match transplantation in African American renal transplant recipients. Am J Transplant 8(2):348-354
9. Haririan A, Nogueira J, Kukuruga D, Schweitzer E, Hess J, Gurk-Turner C et al (2009) Positive cross-match living donor kidney transplantation: longer-term outcomes. Am J Transplant 9(3):536-542
10. Segev DL, Wang JG, Gloor J, Stegall M, Kapur S, Dunn T et al (2011) Risk of HLA incompatible kidney transplants by antibody strength: Initial results from a national study of 603 patients. Am J Transplant 11(Suppl 2):136
11. US Renal Data System (2011) USRDS 2010 annual data report: Atlas of chronic kidney disease and end-stage renal disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
12. Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LY et al (1999) Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 341(23):1725-1730
13. Montgomery RA, Lonze BE, King KE, Kraus ES, Kucirka LM, Locke JE et al (2011) Desensitization in HLAincompatible kidney recipients and survival. N Engl J Med 365(4):318-326
14. Segev DL, Gentry SE, Warren DS, Reeb B, Montgomery RA (2005) Kidney paired donation and optimizing the use of live donor organs. JAMA 293(15):1883-1890
15. Huh KH, Kim SI, Joo DJ, Ju MK, Chang HK, Kim HJ et al (2009) Efficacy of a negative conversion trial and subsequent living donor kidney transplant outcome in recipients with a positive lymphocyte crossmatch. Nephron Clin Pract 111(1):c49-c54
16. Yoon HE, Hyoung BJ, Hwang HS, Lee SY, Jeon YJ, Song JC (2009) Successful renal transplantation with desensitization in highly sensitized patients: a single center experience. J Korean Med Sci 24(Suppl l):S148-S155
17. Kim SM, Lee C, Lee JP, Kim EM, Ha J, Kim SJ (2009) Kidney transplantation in sensitized recipients; a single center experience. J Korean Med Sci 24(SuppL l):S143-S147
18. Garonzik Wang JM, Montgomery RA, Kucirka LM, Berger JC, Warren DS, Segev DL (2011) Incompatible live-donor kidney transplantation in the United States: results of a national survey. Clin J Am Soc Nephrol 6(8):2041-2046
19. Racusen LC, Colvin RB, Solez K, Mihatsch MJ, Halloran PF, Campbell PM et al (2003) Antibody-mediated rejection criteria-an addition to the Banff '97 classification of renal allograft rejection. Am J Transplant 3(6):14-706
20. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D (1999) A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of diet in renal disease study group. Ann Intern Med 130(6):461-470
21. Gloor JM, Winters JL, Cornell LD, Fix LA, DeGoey SR, Knauer RM et al (2010) Baseline donor-specific antibody levels and outcomes in positive crossmatch kidney transplantation. Am J Transplant 10(3):582-589
22. Thielke JJ, West-Thielke PM, Herren HL, Bareato U, Ommert T, Vidanovic V et al (2009) Living donor kidney transplantation across positive crossmatch: the University of Illinois at Chicago experience. Transplantation 87(2): 268-273
23. Vo AA, Peng A, Toyoda M, Kahwaji J, Cao K, Lai CH et al (2010) Use of intravenous immune globulin and rituximab for desensitization of highly HLA-sensitized patients awaiting kidney transplantation. Transplantation 89(9):1095-1102
24. Akalin E, Dinavahi R, Friedlander R, Ames S, de Boccardo G, Sehgal V et al (2008) Addition of plasmapheresis decreases the incidence of acute antibody-mediated rejection in sensitized patients with strong donor-specific antibodies. Clin J Am Soc Nephrol 3(4):1160-1167