The suppression of the glutelin storage protein gene in transgenic rice seeds results in a higher yield of recombinant protein

Plant Biotechnology Reports

Volumn 6, Issue 4, 2012, Pages 347-353

  Kim, Young Mi ^a   Lee, Jong Yeol ^a   Lee, Theresa ^a   Lee, Yeon Hee ^a   Kim, Se Hee ^a   Kang, Sang Ho ^a   Yoon, Ung Han ^a   Ha, Sun Hwa ^a   Lim, Sun Hyung ^a  

^a National Academy of Agricultural Science   (South Korea)

Author keywords

Glutelin; RFP; Rice; RNAi; Seed storage protein; Transgenic crop

Indexed keywords

EID: 84867857667     PISSN: 18635466     EISSN: 18635474     Source Type: Journal    
DOI: 10.1007/s11816-012-0230-7     Document Type: Article

References (33)

1. Fischer R, Emans N (2000) Molecular farming of pharmaceutical proteins. Transgenic Res 9: 279-299.
2. Fischer R, Stoger E, Schilberg S, Christou P, Twyman RM (2004) Plant-based production of biopharmaceuticals. Curr Opin Plant Biol 7: 152-158.
3. Fujiwara Y, Aiki Y, Yang L, Takaiwa F, Kosada A, Tsuji N, Shiraki K, Sekikawa K (2010) Extraction and purification of human interleukin-10 from transgenic rice seeds. Protein Exp Purif 72: 125-130.
4. Goossens A, Montagu MV, Angenon G (1999) Co-introduction an antisense gene for an endogenous seed storage protein can increase expression of a transgene in Arabidopsis thaliana seeds. FEBS Lett 456: 160-164.
5. Ha SH, Liang YS, Jung H, Ahn MJ, Suh SC, Kweon SJ, Kim DH, Kim YM, Kim JK (2010) Application of two bicistronic systems involving 2A and IRES sequences to the biosynthesis of carotenoids in rice endosperm. Plant Biotechnol J 8: 928-938.
6. Hiei Y, Ohta S, Komari T, Kumashiro T (1994) Efficient transformation of rice (Oryza sativa L.) mediated by Agrobacterium and sequence analysis of the boundaries of T-DNA. Plant J 6: 271-282.
7. Jang IC, Choi WB, Lee KH, Song SI, Nahm BH, Kim JK (2002) High-level and ubiquitous expression of the rice cytochrome c gene OsCc1 and its promoter activity in transgenic plants provides a useful promoter for transgenesis of monocots. Plant Physiol 129: 1473-1481.
8. ™ vectors for Agrobacterium-mediated plant transformation. Trends Plant Sci 7: 193-196.
9. Kawakatsu T, Yamamoto M, Hirose S, Yano M, Takaiwa F (2008) Characterization of a new rice glutelin gene GluD-1 expressed in the starchy endosperm. J Exp Bot 59: 4233-4245.
10. Kawasatsu T, Hirose S, Yasuda H, Takaiwa F (2010) Reducing rice seed storage protein accumulation leads to changes in nutrient quality and storage organelle formation. Plant Physiol 154: 1842-1854.
11. Kuribara H, Shindo Y, Matsuoka T, Takubo K, Futo S, Aoki N, Hirao T, Akiyama H, Goda Y, Toyada M, Hino A (2002) Novel reference molecules for quantitation of genetically modified maize and soybean. J AOAC Int 85(5): 1077-1089.
12. Kuroda M, Kizumi M, Mikami C (2010) A simple set of plasmids for the production of transgenic plants. Biosci Biotechnol Biochem 74: 2348-2351.
13. Kusaba M, Miyahara K, Iida S, Fukuoka H, Takano T, Sassa H, Nishimura M, Nishio T (2003) Low glutelin content1: a dominant mutation that suppresses the glutelin multigene family via RNA silencing in rice. Plant Cell 15: 1455-1467.
14. Lee SH, Kang SH, Park YH, Min DM, Kim YM (2006) Quantitative analysis of two genetically modified maize lines by real-time PCR. J Microbiol Biotechnol 16: 205-211.
15. Lin C, Nie P, Lu W, Zhang Q, Li J, Shen Z (2010) A selectively terminable transgenic rice line expressing human lactoferrin. Protein Exp Purif 74: 60-64.
16. Liu W, Liu H, Chai Z, Xu X, Song Y, Qu L (2010) Evaluation of seed storage-protein gene 5′ untranslated regions in enhancing gene expression in transgenic rice seed. Theor Appl Genet 121: 1267-1274.
17. Oh SJ, Song SI, Kim YS, Jang HJ, Kim SY, Kim M, Kim YK, Nahm BH, Kim JK (2005) Arabidopsis CBF4/DREB1A and ABF3 in transgenic rice increased tolerance to abiotic stress without stunting growth. Plant Physiol 138: 341-351.
18. Oono Y, Wakasa Y, Hirose S, Yang L, Sakuta C, Takaiwa F (2010) Analysis of ER stress in developing rice endosperm accumulating beta-amyloid peptide. Plant Biotechnol J 8: 691-718.
19. Qu LQ, Takaiwa F (2004) Evaluation of tissue specificity and expression strength of rice seed component gene promoters in transgenic rice. Plant Biotechnol J 2: 113-115.
20. Qu LQ, Yoshihara T, Ooyama A, Goto Y, Takaiwa F (2005) Iron accumulation does not parallel the high expression level of ferritin in transgenic rice seeds. Planta 222: 225-233.
21. Qu LQ, Xing YP, Liu WX, Xu XP, Song YR (2008) Expression pattern and activity of six glutelin gene promoters in transgenic rice. J Exp Bot 59: 2417-2424.
22. Rho JK, Lee T, Jung SI, Kim TS, Park YH, Kim YM (2004) Qualitative and quantitative PCR methods for detection of three lines of genetically modified potatoes. J Agric Food Chem 52: 3269-3274.
23. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
24. Sardana R, Dudani A, Tackaberry E, Alli Z, Porter S, Rowlandson K, Ganz P, Altosaar I (2007) Biologically active human GM-CSF produced in the seeds of transgenic rice plants. Transgenic Res 16: 713-721.
25. Stoger E, Sack M, Perrin Y, Vaquero C, Torres E, Twyman RM, Christou P, Fisher R (2002) Practical considerations for pharmaceutical antibodies production in different crop systems. Mol Breed 9: 149-158.
26. Stoger E, Ma JKC, Fisher R, Christou P (2005) Sowing the seeds of success: pharmaceutical proteins from plants. Curr Opin Biotechnol 16: 167-173.
27. Su C, Xie J, Wang X, Peng Y (2011) Integrated structure and event-specific real-time detection of transgenic cry1Ac/SCK rice Kefeng 6. Eur Food Res Technol 232: 351-359.
28. Sundaresan V, Springer P, Volpe T, Haward S, Jones JD, Dean C, Ma H, Martienssen R (1995) Patterns of gene action in plant development revealed by enhancer trap and gene trap transposable elements. Gene Dev 9: 1797-1810.
29. Takaiwa F, Takagi H, Hirose S, Wakasa Y (2007) Endosperm tissue is good production platform for artificial recombinant proteins in transgenic rice. Plant Biotechnol J 5: 84-92.
30. Wu CY, Adachi T, Hatano T, Washida H, Suzuki A, Takaiwa F (1998) Promoters of rice seed storage protein genes direct endosperm-specific gene expression in transgenic rice. Plant Cell Physiol 39: 885-889.
31. Yang LJ, Tada Y, Yamamoto MP, Zhao H, Yoshikawa M, Takaiwa F (2006) A transgenic rice seed accumulating an anti-hypertensive peptide reduces the blood pressure of spontaneously hypertensive rats. FEBS Lett 580: 3315-3320.
32. Yang L, Wakasa Y, Kawasatsu T, Takaiwa F (2009) The 3′-untranslated region of rice glutelin GluB-1 affects accumulation of heterologous protein in transgenic rice. Biotechnol Lett 31: 1625-1631.
33. Zhang D, Nandi S, Bryan P, Pettit S, Nguyen D, Santos M, Huang N (2010) Expression, purification, and characterization of recombinant human transferring from rice (Oryza sativa L.). Protein Exp Purif 74: 69-79.