Synthesis of pyrazole peptidomimetics and their inhibition against A549 lung cancer cells

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 22, 2012, Pages 6882-6887

  Liu, Ying Rui ^a   Luo, Ji Zhuang ^a   Duan, Pan Pan ^a   Shao, Jing ^a   Zhao, Bao Xiang ^a   Miao, Jun Ying ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

A549; Anticancer; Peptidomimetics; Pyrazole; Synthesis

Indexed keywords

ANTINEOPLASTIC AGENT; PEPTIDOMIMETIC AGENT; PYRAZOLE DERIVATIVE; PYRAZOLE PEPTIDOMIMETIC DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; LUNG CANCER; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CARBOXYLIC ACIDS; CELL LINE, TUMOR; G1 PHASE CELL CYCLE CHECKPOINTS; HUMANS; PEPTIDOMIMETICS; PYRAZOLES; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84867847124     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.09.032     Document Type: Article

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