Site directed vascular gene delivery in vivo by ultrasonic destruction of magnetic nanoparticle coated microbubbles

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 8, Issue 8, 2012, Pages 1309-1318

  Mannell, Hanna ^a   Pircher, Joachim ^a   Fochler, Franziska ^a   Stampnik, Yvonn ^a   Räthel, Thomas ^a   Gleich, Bernhard ^b   Plank, Christian ^b   Mykhaylyk, Olga ^b   Dahmani, Chiheb ^b   Wörnle, Markus ^a   Ribeiro, Andrea ^a   Pohl, Ulrich ^a   Krötz, Florian ^a,c  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c Interventional Cardiology Starnberg Community Hospital   (Germany)

Author keywords

Endothelial cells; Gene delivery; Magnetic nanoparticles; Microbubbles; Ultrasound

Indexed keywords

GENE DELIVERY; IN-VITRO; IN-VIVO; MAGNETIC FORCE; MAGNETIC NANOPARTICLES; MAGNETIC TRAPPING; MICRO-BUBBLE; MICROBUBBLES; PLASMID DNA; SIDE EFFECT; SITE-SPECIFIC; TARGETED GENE DELIVERY; THERAPEUTIC POTENTIALS; ULTRASONIC DESTRUCTION; VASCULAR SYSTEM; VASCULAR WALL; VASCULATURE;

ENDOTHELIAL CELLS; NANOPARTICLES; TECHNOLOGY; ULTRASONIC APPLICATIONS; ULTRASONICS;

GENE TRANSFER;

MAGNETIC NANOPARTICLE; OLIGONUCLEOTIDE; PLASMID DNA; SMALL DNA OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD VESSEL WALL; CARDIOVASCULAR SYSTEM; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MAGNETISM; MICROBUBBLE; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; TISSUE SPECIFICITY; ULTRASOUND; WESTERN BLOTTING;

DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HUMANS; MAGNETITE NANOPARTICLES; MICROBUBBLES; PLASMIDS; ULTRASONICS;

EID: 84867842607     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2012.03.007     Document Type: Article

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