A validated LC method for the determination of the enantiomeric purity of aliskiren hemifumarate in bulk drug samples

Journal of Chromatographic Science

Volumn 50, Issue 9, 2012, Pages 799-802

  Ashok, Sigala ^a   Varma, M Satish ^a   Swaminathan, Srinivasan ^a  

^a DR REDDY'S LABORATORIES LTD   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALISKIREN; AMIDE; FUMARIC ACID DERIVATIVE;

ARTICLE; CHEMISTRY; DRUG CONTAMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INSTRUMENTATION; LIMIT OF DETECTION; METHODOLOGY; REPRODUCIBILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; STEREOISOMERISM; ULTRAVIOLET SPECTROPHOTOMETRY;

AMIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; DRUG CONTAMINATION; FUMARATES; LIMIT OF DETECTION; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM;

EID: 84867828986     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/bms073     Document Type: Article

References (9)

1. Franco, P., Zhang, T.; Common approaches for efficient method development with immobilised polysaccharidederived chiral stationary phases; Journal of Chromatography B, (2008); 875: 48-56.
2. Zhang, T., Nguyen, D., Franco, P.; Enantiomer resolution screening strategy using multiple immobilized polysaccharide based chiral stationary phases; Journal of Chromatography A, (2008); 1191: 214-222.
3. Zhang, T., Nguyen, D., Franco, P., Isobe, Y., Michishita, T., Murakami, T.; Cellulose tris (3, 5-dichlorophenylcarbamate) immobilised on silica: a novel chiral stationary phase for resolution of enantiomers; Journal of Pharmaceutical and Biomedical Analysis, (2008); 46: 882-891. (Pubitemid 351400611)
4. Aboul-Enein, H.Y.; High-performance liquid chromatographic enantioseparation of drugs containing multiple chiral centers on polysaccharide-type chiral stationary phases; Journal of Chromatography A, (2001); 906: 185-193.
5. Pachauri, S., Paliwal, S., Srinivas, K.S., Singh, Y., Jain, V.; Development & validation of HPLC method for analysis of some antihypertensive agents in their pharmaceutical dosage forms; Journal of Pharmaceutical Sciences and Research, (2010); 8: 459-464.
6. Lefevre, G., Gauron, S.; Automated quantitative determination of the new renin inhibitor CGP 60536 by high-performance liquid chromatography; Journal of Chromatography B, (2000); 738: 129-136. (Pubitemid 30053100)
7. Sheshagiri Rao, J.V.L.N., Rajendra Kumar, J.M., Ashok Kumar, U., Bikshapathi, D.V.R.N., Vinay Kumar, D.; Analytical method development and validation of aliskiren in bulk and tablet dosage form by RP-HPLC method; Journal of Pharmacy and Research, (2011); 4(3): 865-867.
8. Cirilli, R., Ferretti, R., De Santis, E., Gallinella, B., Zanitti, L., La Torre, F.; High-performance liquid chromatography separation of enantiomers of flavanone and 2-hydroxychalcone under reversed-phase conditions; Journal of Chromatography A, (2008); 1190: 95-101.
9. Cirilli, R., Ferretti, R., Gallinella, B., De Santis, E., Zanitti, L., La Torre, F.; High-performance liquid chromatography enantioseparation of proton pump inhibitors using the immobilized amylose-based Chiralpak IA chiral stationary phase in normal-phase, polar organic and reversed-phase conditions; Journal of Chromatography A, (2008); 1177: 105-113. (Pubitemid 350256753)