Involvement of PU.1 in mast cell/ basophil-specific function of the human IL1RL1/ST2 promoter

Allergology International

Volumn 61, Issue 3, 2012, Pages 461-467

  Baba, Yosuke ^a   Maeda, Keiko ^a   Yashiro, Takuya ^a   Inage, Eisuke ^a   Niyonsaba, Françis ^a   Hara, Mutsuko ^a   Suzuki, Ryuyo ^a   Ohtsuka, Yoshikazu ^a   Shimizu, Toshiaki ^a   Ogawa, Hideoki ^a   Okumura, Ko ^a   Nishiyama, Chiharu ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Basophils; IL1RL1 ST2; Il33 receptor; Mast cells; PU.1

Indexed keywords

CYTOKINE; INTERLEUKIN 1 RECEPTOR LIKE 1 PROTEIN; INTERLEUKIN 33; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR PU 1; UNCLASSIFIED DRUG;

ARTICLE; BASOPHIL; CONTROLLED STUDY; HUMAN; HUMAN CELL; MAST CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; REGULATORY MECHANISM;

EID: 84867815126     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.12-OA-0424     Document Type: Article

References (26)

1. Schmitz J, Owyang A, Oldham E et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2- associated cytokines. Immunity 2005;23:479-490.
2. Liew FY, Pitman NI, McInnes IB. Disease-associated functions of IL-33: The new kid in the IL-1 family. Nat Rev Immunol 2010;10:103-110.
3. Xu D, Jiang HR, Kewin P et al. IL-33 exacerbates antigeninduced arthritis by activating mast cells. Proc Natl Acad Sci U S A 2008;105:10913-10918.
4. Allakhverdi Z, Smith DE, Comeau MR, Delespesse G. Cutting edge: The ST2 ligand IL-33 potently activates and drives maturation of human mast cells. J Immunol 2007; 179:2051-2054.
5. Pushparaj PN, Tay HK, H'Ng SC et al. The cytokine interleukin-33 mediates anaphylactic shock. Proc Natl Acad Sci U S A 2009;106:9773-9778.
6. Schneider E, Petit-Bertron AF, Bricard R et al. IL-33 activates unprimed murine basophils directly in vitro and induces their in vivo expansion indirectly by promoting hematopoietic growth factor production. J Immunol 2009; 183:3591-3597.
7. Pecaric-Petkovic T, Didichenko SA, Kaempfer S, Spiegl N, Dahinden CA. Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. Blood 2009;113:1526-1534.
8. Suzukawa M, Iikura M, Koketsu R et al. An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J Immunol 2008;181:5981-5989.
9. Iwahana H, Yanagisawa K, Ito-Kosaka A et al. Different promoter usage and multiple transcription initiation sites of the interleukin-1 receptor-related human ST2 gene in UT-7 and TM12 cells. Eur J Biochem 1999;264:397-406.
10. Gachter T, Moritz DR, Gheyselinck J, Klemenz R. GAT Adependent expression of the interleukin-1 receptorrelated T1 gene in mast cells. Mol Cell Biol 1998;18:5320-5331.
11. Hayakawa M, Yanagisawa K, Aoki S, Hayakawa H, Takezako N, Tominaga S. T-helper type 2 cell-specific expression of the ST2 gene is regulated by transcription factor GATA-3. Biochim Biophys Acta 2005;1728:53-64.
12. Nishiyama C, Hasegawa M, Nishiyama M et al. Regulation of human Fc epsilon RI alpha-chain gene expression by multiple transcription factors. J Immunol 2002;168: 4546-4552.
13. Walsh JC, DeKoter RP, Lee HJ et al. Cooperative and antagonistic interplay between PU.1 and GATA-2 in the specification of myeloid cell fates. Immunity 2002;17:665-676.
14. Kirshenbaum AS, Akin C, Wu Y et al. Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma /leukemia; activation following aggregation of FcepsilonRI or FcgammaRI. Leuk Res 2003;27:677-682.
15. Niyonsaba F, Ushio H, Hara M et al. Antimicrobial peptides human beta-defensins and cathelicidin IL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. J Immunol 2010;184:3526-3534.
16. Maeda K, Nishiyama C, Ogawa H, Okumura K. GATA2 and Sp1 positively regulate the c-kit promoter in mast cells. J Immunol 2010;185:4252-4260.
17. Maeda K, Nishiyama C, Tokura T et al. FOG-1 represses GATA-1-dependent FcepsilonRI beta-chain transcription: Transcriptional mechanism of mast-cell-specific gene expression in mice. Blood 2006;108:262-269.
18. Nishiyama C, Yokota T, Okumura K, Ra C. The transcription factors Elf-1 and GATA-1 bind to cell-specific enhancer elements of human high-affinity IgE receptor alphachain gene. J Immunol 1999;163:623-630.
19. Nishiyama C, Akizawa Y, Nishiyama M et al. Polymorphisms in the Fc epsilon RI beta promoter region affecting transcription activity: A possible promoter-dependent mechanism for association between Fc epsilon RI beta and atopy. J Immunol 2004;173:6458-6464.
20. Kanada S, Nakano N, Potaczek DP et al. Two different transcription factors discriminate the -315C > T polymorphism of the Fc epsilon RI alpha gene: Binding of Sp1 to -315C and of a high mobility group-related molecule to -315T. J Immunol 2008;180:8204-8210.
21. Kanada S, Nishiyama C, Nakano N et al. Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells. Blood 2011;117:2211-2222.
22. Henkel G, Brown MA. PU.1 and GATA: Components of a mast cell-specific interleukin 4 intronic enhancer. Proc Natl Acad Sci U S A 1994;91:7737-7741.
23. Rekhtman N, Radparvar F, Evans T, Skoultchi AI. Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: Functional antagonism in erythroid cells. Genes Dev 1999;13:1398-1411.
24. Nerlov C, Querfurth E, Kulessa H, Graf T. GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription. Blood 2000;95: 2543-2551.
25. Zhang P, Behre G, Pan J et al. Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Proc Natl Acad Sci U S A 1999;96:8705-8710.
26. Matsumura I, Kawasaki A, Tanaka H et al. Biologic significance of GATA-1 activities in Ras-mediated megakaryocytic differentiation of hematopoietic cell lines. Blood 2000;96:2440-2450.