1-methylthio-d-xylulose 5-phosphate methylsulfurylase: A novel route to 1-deoxy-d-xylulose 5-phosphate in Rhodospirillum rubrum

Biochemistry

Volumn 51, Issue 42, 2012, Pages 8324-8326

  Warlick, Benjamin P ^a,b   Evans, Bradley S ^b   Erb, Tobias J ^a,b,f   Ramagopal, Udipi A ^d,g   Sriram, Jaya ^c   Imker, Heidi J ^b   Sauder, J Michael ^e   Bonanno, Jeffrey B ^d   Burley, Stephen K ^e   Tabita, F Robert ^c   Almo, Steven C ^d   Sweedler, Jonathan S ^b   Gerlt, John A ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e ELI LILLY AND COMPANY   (United States)

^f ETH ZURICH   (Switzerland)

^g POORNAPRAJNA INSTITUTE OF SCIENTIFIC RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ENOLATES; ISOPRENOIDS; METHYL DISULFIDES; NOVEL ROUTE; POLYAMINES; RHODOSPIRILLUM RUBRUM; S-ADENOSYLMETHIONINE; SALVAGE PATHWAY;

AMINO ACIDS; BIOCHEMISTRY;

OLEFINS;

1 DEOXY DEXTRO XYLULOSE 5 PHOSPHATE; 1 METHYLTHIO DEXTRO XYLULOSE 5 PHOSPHATE METHYLSULFURYLASE; CYSTEINE; ISOPRENOID; PHOSPHORUS ACID DERIVATIVE; SULFATE ADENYLYLTRANSFERASE; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION KINETICS; MASS SPECTROMETRY; METHYLATION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; RHODOSPIRILLUM RUBRUM;

METABOLIC NETWORKS AND PATHWAYS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PENTOSEPHOSPHATES; RHODOSPIRILLUM RUBRUM; RIBOSEMONOPHOSPHATES; SULFURTRANSFERASES; THIOGLYCOSIDES;

EID: 84867794049     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301215g     Document Type: Article

References (6)

1. Tabita, F. R., Hanson, T. E., Li, H., Satagopan, S., Singh, J., and Chan, S. (2007) Microbiol. Mol. Biol. Rev. 71, 576-599
2. Tabita, F. R., Hanson, T. E., Satagopan, S., Witte, B. H., and Kreel, N. E. (2008) Philos. Trans. R. Soc. London, Ser. B 363, 2629-2640
3. Ashida, H., Saito, Y., Kojima, C., Kobayashi, K., Ogasawara, N., and Yokota, A. (2003) Science 302, 286-290
4. Imker, H. J., Singh, J., Warlick, B. P., Tabita, F. R., and Gerlt, J. A. (2008) Biochemistry 47, 11171-11173
5. Erb, T. J., Evans, B. S., Cho, K., Warlick, B. P., Singh, J., Wood, B. M., Imker, H. J., Sweedler, J. V., Tabita, F. R., and Gerlt, J. A. (2012) Nat. Chem. Biol. in press
6. Warner, J. R., Behlen, L. S., and Copley, S. D. (2008) Biochemistry 47, 3258-3265