Hemosuccus pancreaticus: A rare cause of gastrointestinal bleeding

Hepatobiliary and Pancreatic Diseases International

Volumn 11, Issue 5, 2012, Pages 479-488

  Han, Bing ^a   Song, Zeng Fu ^a   Sun, Bei ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Gastrointestinal hemorrhage; Hemorrhagic pseudocyst; Hemosuccus pancreaticus; Pseudoaneurysm

Indexed keywords

CARBON DIOXIDE; TECHNETIUM 99M; TRYPSIN; TRYPSINOGEN;

ABDOMINAL PAIN; ACUTE PANCREATITIS; ANGIOGRAPHY; ARTIFICIAL EMBOLISM; BRUCELLOSIS; CHRONIC PANCREATITIS; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; DISEASE ASSOCIATION; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; ENDOSCOPY; FALSE ANEURYSM; GASTROINTESTINAL HEMORRHAGE; GENE MUTATION; HEMOSUCCUS PANCREATICUS; HUMAN; HYPERAMYLASEMIA; IATROGENIC DISEASE; MEDLINE; NEOPLASM; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PORTAL HYPERTENSION; REVIEW; THROMBOSIS; VASCULAR DISEASE;

EID: 84867792385     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1499-3872(12)60211-2     Document Type: Review

References (86)

1. Sakorafas GH, Sarr MG, Farley DR, Que FG, Andrews JC, Farnell MB. Hemosuccus pancreaticus complicating chronic pancreatitis: an obscure cause of upper gastrointestinal bleeding. Langenbecks Arch Surg 2000;385:124-128.
2. Sandblom P. Gastrointestinal hemorrhage through the pancreatic duct. Ann Surg 1970;171:61-66.
3. Lermite E, Regenet N, Tuech JJ, Pessaux P, Meurette G, Bridoux V, et al. Diagnosis and treatment of hemosuccus pancreaticus: development of endovascular management. Pancreas 2007;34:229-232.
4. Frayssinet R, Sahel J, Sarles H. Wirsungorrhagia. Report of a case and review of the literature (author's transl). Gastroenterol Clin Biol 1978;2:993-1000.
5. Vázquez-Iglesias JL, Durana JA, Yañez J, Rodriguez H, Garcia-Vallejo L, Arnal F. Santorinirrhage: hemosuccus pancreaticus in pancreas divisum. Am J Gastroenterol 1988;83:876-878.
6. Pinarbaşi B, Poturoǧlu S, Yanar H, Güven K, Akyüz F, Dizdaroǧlu F, et al. A rare cause of hemosuccus pancreaticus: primary splenic artery aneurysm ruptured into pancreatic serous cystadenoma. Turk J Gastroenterol 2008;19:57-63.
7. Longmire WP Jr, Rose AS 3rd. Hemoductal pancreatitis. Surg Gynecol Obstet 1973;136:246-250.
8. Yokoyama I, Hashmi MA, Srinivas D, Shaikh KA, Levine SM, Sorokin JJ, et al. Wirsungorrhagia or hemoductal pancreatitis: report of a case and review of the literature. Am J Gastroenterol 1984;79:764-768.
9. Péroux JL, Arput JP, Saint-Paul MC, Dumas R, Hastier P, Caroli FX, et al. Wirsungorrhagia complicating chronic pancreatitis associated with a neuroendocrine tumor of the pancreas. Gastroenterol Clin Biol 1994;18:1142-1145.
10. Kapoor S, Rao P, Pal S, Chattopadhyay TK. Hemosuccus pancreaticus: an uncommon cause of gastrointestinal hemorrhage. A case report. JOP 2004;5:373-376.
11. Risti B, Marincek B, Jost R, Decurtins M, Ammann R. Hemosuccus pancreaticus as a source of obscure upper gastrointestinal bleeding: three cases and literature review. Am J Gastroenterol 1995;90:1878-1880.
12. El Hamel A, Parc R, Adda G, Bouteloup PY, Huguet C, Malafosse M. Bleeding pseudocysts and pseudoaneurysms in chronic pancreatitis. Br J Surg 1991;78:1059-1063.
13. Arnaud JP, Bergamaschi R, Serra-Maudet V, Casa C. Pancreatoduodenectomy for hemosuccus pancreaticus in silent chronic pancreatitis. Arch Surg 1994;129:333-334.
14. Maus TP. Pseudoaneurysm hemorrhage as a complication of pancreatitis. Mayo Clin Proc 1993;68:895-896.
15. Stanley JC, Frey CF, Miller TA, Lindenauer SM, Child CG 3rd. Major arterial hemorrhage: a complication of pancreatic pseudocysts and chronic pancreatitis. Arch Surg 1976;111:435-440.
16. Camishion RC, Pello MJ, Spence RK, Alexander JB, Atabek UM, Kuroda K. Hemoductal pancreatitis. Surgery 1992;111: 86-89.
17. Marescaux J, Evrard S, Aprahamian M, Stock-Damge C, Coumaros D, Sibilly A. Pancreatic lithiasis: a rare cause of gastrointestinal hemorrhage. Surgery 1989;105:682-685.
18. Eckhauser FE, Stanley JC, Zelenock GB, Borlaza GS, Freier DT, Lindenauer SM. Gastroduodenal and pancreaticoduodenal artery aneurysms: a complication of pancreatitis causing spontaneous gastrointestinal hemorrhage. Surgery 1980;88: 335-344.
19. Steckman ML, Dooley MC, Jaques PF, Powell DW. Major gastrointestinal hemorrhage from peripancreatic blood vessels in pancreatitis. Treatment by embolotherapy. Dig Dis Sci 1984;29:486-497.
20. Pungpapong S, Raimondo M. Hepatic and splenic arteries' pseudoaneurysms causing hemosuccus pancreaticus. JOP 2004;5:395-396.
21. Bender JS, Bouwman DL, Levison MA, Weaver DW. Pseudocysts and pseudoaneurysms: surgical strategy. Pancreas 1995;10:143-147.
22. Heath DI, Reid AW, Murray WR. Bleeding pseudocysts and pseudoaneurysms in chronic pancreatitis. Br J Surg 1992;79: 281.
23. Smith RE, Fontanez-Garcia D, Plavsic BM. Gastrointestinal case of the day. Pseudoaneurysm of the left gastric artery as a complication of acute pancreatitis. Radiographics 1999;19: 1390-1392.
24. Jin S, Dong X, Ping C. Image of the month. Pancreaticoduodenal artery and superior mesenteric artery pseudoaneurysm associated with hemosuccus pancreaticus. Clin Gastroenterol Hepatol 2010;8:e11-12.
25. Glaser K, Bodner E, Wetscher G, Weger A, Tschmelitsch J, Klingler P, et al. Hemorrhage from the pancreatic duct caused by a splenic vein fistula. Endoscopy 1994;26:268-269.
26. Shah S, Barkin JS. Hemosuccus pancreaticus: a new mechanism. Pancreas 2011;40:317-318.
27. Mizutamari H, Masamune A, Asakura T, Nagasaki Y, Satoh A, Sakai Y, et al. A case of hemosuccus pancreaticus associated with hereditary pancreatitis. Tohoku J Exp Med 2001;195:191-195.
28. Dinu F, Devière J, Van Gossum A, Golzarian J, Dussaussois L, Delhaye M, et al. The wirsungorrhagies: causes and management in 14 patients. Endoscopy 1998;30:595-600.
29. Kanno A, Satoh K, Hamada S, Hirota M, Masamune A, Motoi F, et al. Serous cystic neoplasms of the whole pancreas in a patient with von Hippel-Lindau disease. Intern Med 2011;50: 1293-1298.
30. Williams DM, Shetzline MA, Guarisco SA, Branch MS. Presumed arteriovenous malformation mimicking hemosuccus pancreaticus of Santorini's duct with normal pancreatic anatomy. Gastrointest Endosc 1996;44:348-350.
31. Mizukami Y, Arisato S, Satou K, Nakano Y, Ohta T, Ohta H, et al. A case of anaplastic carcinoma of the pancreas, disclosed a hemosuccus pancreaticus. Nihon Shokakibyo Gakkai Zasshi 1997;94:706-711.
32. Shan YS, Sy ED, Tsai HM, Lin PW. Chronic hemosuccus pancreaticus: a rare complication of pancreatic microcystic adenoma successfully treated with Whipple's procedure. Pancreas 2000;20:416-418.
33. Dupre MP, Dixon E, Heitman SJ. Primary pancreatic lymphoma: a rare cause of massive upper gastrointestinal hemorrhage. Can J Gastroenterol 2011;25:532-533.
34. Shinzeki M, Hori Y, Fujino Y, Matsumoto I, Toyama H, Tsujimura T, et al. Mucinous cystic neoplasm of the pancreas presenting with hemosuccus pancreaticus: report of a case. Surg Today 2010;40:470-473.
35. Tongio J, Peruta O, Wenger JJ, Warter P. Duodenal and pancreatic metastases of nephro-epithelioma (author's transl). Ann Radiol (Paris) 1977;20:641-647.
36. Kassabian A, Stein J, Jabbour N, Parsa K, Skinner D, Parekh D, et al. Renal cell carcinoma metastatic to the pancreas: a single-institution series and review of the literature. Urology 2000;56:211-215.
37. Kurland J, Matthews T, Hoff E, Gentry A, Cash B. Hemosuccus pancreaticus caused by metastatic renal cell carcinoma. Gastrointest Endosc 2007;66:1241-1242.
38. Etienne S, Pessaux P, Tuech JJ, Lada P, Lermite E, Brehant O, et al. Hemosuccus pancreaticus: a rare cause of gastrointestinal bleeding. Gastroenterol Clin Biol 2005;29:237-242.
39. de Perrot M, Bühler L, Deléaval J, Borisch B, Mentha G, Morel P. Management of true aneurysms of the splenic artery. Am J Surg 1998;175:466-468.
40. Jakobs R, Riemann JF. Hemosuccus pancreaticus due to a pressure ulcer in pancreatolithiasis. Dtsch Med Wochenschr 1992;117:1956-1961.
41. Shahani RB, Bijlani RS, Dalvi AN, Shah HK, Samsi AB. Massive upper gastrointestinal haemorrhage due to direct visceral erosion of splenic artery aneurysm. J Postgrad Med 1994;40:220-222.
42. Wagner WH, Cossman DV, Treiman RL, Foran RF, Levin PM, Cohen JL. Hemosuccus pancreaticus from intraductal rupture of a primary splenic artery aneurysm. J Vasc Surg 1994;19:158-164.
43. Massani M, Bridda A, Caratozzolo E, Bonariol L, Antoniutti M, Bassi N. Hemosuccus pancreaticus due to primary splenic artery aneurysm: a diagnostic and therapeutic challenge. JOP 2009;10:48-52.
44. Fazel I, Asle Soleimani H, Fallah S, Babaei M, Sedighi N, Marashi A, et al. Hemosuccus pancreaticus in a patient with celiac trunk aneurysm. Arch Iran Med 2008;11:658-661.
45. Wang WL, Lee JY, Lin JT, Liu KL, Wang HP. A rare cause of obscure gastrointestinal bleeding. Gut 2008;57:878, 886.
46. Naitoh I, Ando T, Shimohira M, Nakazawa T, Hayashi K, Okumura F, et al. Hemosuccus pancreaticus associated with segmental arterial mediolysis successfully treated by transarterial embolization. JOP 2010;11:625-629.
47. Obara H, Matsubara K, Inoue M, Nakatsuka S, Kuribayashi S, Kitagawa Y. Successful endovascular treatment of hemosuccus pancreaticus due to splenic artery aneurysm associated with segmental arterial mediolysis. J Vasc Surg 2011;54:1488-1491.
48. Singh P, Gelrud A, Schmulewitz N, Chauhan S. Hemosuccus pancreaticus after EUS-FNA of pancreatic cyst (with video). Gastrointest Endosc 2008;67:543.
49. Keswani RN. Hemosuccus pancreaticus after endoscopic ultrasound-guided fine needle aspiration of a pancreatic cyst. Endoscopy 2010;42:E79.
50. Seicean A, Stan-Iuga R, Munteanu D. An unusual cause of hemosuccus pancreaticus diagnosed by endoscopic ultrasonography: splenic arterial fistula due to a pancreatic stent (with video). Endoscopy 2010;42:E239-240.
51. Meneu JA, Fernandez-Cebrian JM, Alvarez-Baleriola I, Barrasa A, Morales V, Carda P. Hemosuccus pancreaticus in a heterotopic jejunal pancreas. Hepatogastroenterology 1999; 46:177-179.
52. Suttor VP, Biankin AV, Chin WK, Chow C, Biankin SA, Merrett ND, et al. Pancreatic anomaly with multiple endocrine neoplasia type 1: a case of pancreas divisum and hemosuccus pancreaticus (santorinirrhage). Pancreas 2008; 36:314-315.
53. Belo AC, Grabowski EW, Zhang C, Longworth DL, Desilets DJ. Case of chronic pancreatic brucellosis presenting as hemosuccus pancreaticus. JOP 2007;8:429-432.
54. Pasha SF, Blair JE, Garvey PB, Gray RJ, Mulligan DC, Collins JM, et al. Hemosuccus pancreaticus in the era of capsule endoscopy and double balloon enteroscopy complicated by multifocal mycobacterium chelonae/abscessus infection. Case Rep Gastroenterol 2007;1:38-47.
55. Kim SS, Roberts RR, Nagy KK, Joseph K, Bokhari F, An G, et al. Hemosuccus pancreaticus after penetrating trauma to the abdomen. J Trauma 2000;49:948-950.
56. Izadyar S, Toogeh G, Eftekhari M, Gholamrezanezhad A. Hemosuccus pancreaticus in Glanzmann thrombasthenia: implication of scintigraphy in gastrointestinal bleeding (GIB) of unknown origin. Clin Nucl Med 2011;36:597-598.
57. Harper PC, Gamelli RL, Kaye MD. Recurrent hemorrhage into the pancreatic duct from a splenic artery aneurysm. Gastroenterology 1984;87:417-420.
58. Werner C, Bonnevie B. Gastrointestinal bleeding from a fistula between an aneurysm of the hepatic artery and the pancreatic duct. Eur J Vasc Surg 1993;7:95-97.
59. van Rooyen W, van Blankenstein M, Eeftinck Schattenkerk M, de Vries JE, Obertop H, Bruining HA, et al. Haemorrhage from the pancreatic duct: a rare form of upper gastrointestinal bleeding. Br J Surg 1984;71:137-140.
60. Rohner A. Severe digestive hemorrhage caused by rupture of an aneurysm of the splenic artery into the pancreatic ducts. Gastroenterologia 1967;108:31-43.
61. Suter M, Doenz F, Chapuis G, Gillet M, Sandblom P. Haemorrhage into the pancreatic duct (Hemosuccus pancreaticus): recognition and management. Eur J Surg 1995; 161:887-892.
62. Clay RP, Farnell MB, Lancaster JR, Weiland LH, Gostout CJ. Hemosuccus pancreaticus. An unusual cause of upper gastrointestinal bleeding. Ann Surg 1985;202:75-79.
63. Castillo-Sang M, Higgins JA, Tsang AW, Cason F, Sferra J, Mancho S. Hemosuccus pancreaticus. Am Surg 2009;75:865-867.
64. Bohl JL, Dossett LA, Grau AM. Gastroduodenal artery pseudoaneurysm associated with hemosuccus pancreaticus and obstructive jaundice. J Gastrointest Surg 2007;11:1752-1754.
65. Lacey SR, Chak A. Hemosuccus pancreaticus: dorsal pancreatic duct stone and gastroduodenal artery pseudoaneurysm. Gastrointest Endosc 2001;54:363.
66. Levy MJ, Wong Kee Song LM, Farnell MB, Misra S, Sarr MG, Gostout CJ. Endoscopic ultrasound (EUS)-guided angiotherapy of refractory gastrointestinal bleeding. Am J Gastroenterol 2008;103:352-359.
67. Benz CA, Jakob P, Jakobs R, Riemann JF. Hemosuccus pancreaticus-a rare cause of gastrointestinal bleeding: diagnosis and interventional radiological therapy. Endoscopy 2000;32:428-431.
68. Badea R, Seicean A, Procopet B, Dina L, Osian G. Pseudoaneurysm of splenic artery ruptured in pancreatic pseudocyst and complicated by wirsungorrhagia: the role of the ultrasound techniques and contrast substances. Ultraschall Med 2011;32:205-207.
69. Koizumi J, Inoue S, Yonekawa H, Kunieda T. Hemosuccus pancreaticus: diagnosis with CT and MRI and treatment with transcatheter embolization. Abdom Imaging 2002;27:77-81.
70. de Perrot M, Berney T, Bühler L, Delgadillo X, Mentha G, Morel P. Management of bleeding pseudoaneurysms in patients with pancreatitis. Br J Surg 1999;86:29-32.
71. Contro A, Carbognin G, Genovese G, Mansueto G. Haemosuccus pancreaticus in chronic pancreatitis: direct diagnosis by CT. Dig Liver Dis 2011;43:e11.
72. Ray S, Das K, Ray S, Khamrui S, Ahammed M, Deka U. Hemosuccus pancreaticus associated with severe acute pancreatitis and pseudoaneurysms: a report of two cases. JOP 2011;12:469-472.
73. Miki S, Mori K, Masanari S, Furuta T, Saida T, Hiratsuka M, et al. Hemosuccus pancreaticus in a patient with iodine allergy: successful diagnosis with magnetic resonance imaging and treatment with transarterial embolization using carbon dioxide as the contrast medium. Cardiovasc Intervent Radiol 2009;32:1296-1299.
74. Tabrizian P, Newell P, Reiter BP, Heimann TM. Successful multimodality treatment for hemosuccus pancreaticus. Am J Gastroenterol 2009;104:1060.
75. Stabile BE, Wilson SE, Debas HT. Reduced mortality from bleeding pseudocysts and pseudoaneurysms caused by pancreatitis. Arch Surg 1983;118:45-51.
76. Gambiez LP, Ernst OJ, Merlier OA, Porte HL, Chambon JP, Quandalle PA. Arterial embolization for bleeding pseudocysts complicating chronic pancreatitis. Arch Surg 1997;132:1016-1021.
77. Sethi H, Peddu P, Prachalias A, Kane P, Karani J, Rela M, et al. Selective embolization for bleeding visceral artery pseudoaneurysms in patients with pancreatitis. Hepatobiliary Pancreat Dis Int 2010;9:634-638.
78. Zyromski NJ, Vieira C, Stecker M, Nakeeb A, Pitt HA, Lillemoe KD, et al. Improved outcomes in postoperative and pancreatitis-related visceral pseudoaneurysms. J Gastrointest Surg 2007;11:50-55.
79. Akpinar H, Dicle O, Ellidokuz E, Okan A, Göktay Y, Tankurt E, et al. Hemosuccus pancreaticus treated by transvascular selective arterial embolization. Endoscopy 1999;31:213-214.
80. Huizinga WK, Kalideen JM, Bryer JV, Bell PS, Baker LW. Control of major haemorrhage associated with pancreatic pseudocysts by transcatheter arterial embolization. Br J Surg 1984;71:133-136.
81. Knight RW, Kadir S, White RI Jr. Embolization of bleeding transverse pancreatic artery aneurysms. Cardiovasc Intervent Radiol 1982;5:37-39.
82. Morse JM, Reddy KR, Thomas E. Hemosuccus pancreaticus: a cause for obscure gastrointestinal bleeding-diagnosis by endoscopy and successful management by total parenteral nutrition. Am J Gastroenterol 1983;78:572-574.
83. Waltman AC, Luers PR, Athanasoulis CA, Warshaw AL. Massive arterial hemorrhage in patients with pancreatitis. Complementary roles of surgery and transcatheter occlusive techniques. Arch Surg 1986;121:439-443.
84. Sand JA, Seppänen SK, Nordback IH. Intracystic hemorrhage in pancreatic pseudocysts: initial experiences of a treatment protocol. Pancreas 1997;14:187-191.
85. Strömmer L, Albiin N, Calissendorff B, Granlund H, Permert J. Diagnosis and treatment of hemosuccus pancreaticus during a nonbleeding episode: A case report of a patient with obscure intermittent gastrointestinal bleeding and silent chronic pancreatitis. Pancreatology 2004;4:7-11.
86. Will U, Mueller AK, Grote R, Meyer F. "Hemosuccus pancreaticus"-primarily ultrasound-guided successful intervention using transcutaneous fibrin glue application and histoacryl injection. Ultraschall Med 2008;29:260-263.