Resolving the negative potential side (n-side) water-accessible proton pathway of F-type ATP synthase by molecular dynamics simulations

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 36536-36543

  Gohlke, Holger ^a   Schlieper, Daniel ^a   Groth, Georg ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC RESOLUTION; ATP SYNTHASE; ATP SYNTHESIS; CLOCKWISE ROTATION; CURRENT MODELS; MOLECULAR DYNAMICS SIMULATIONS; MOLECULAR FUNCTION; NEGATIVE POTENTIAL; PROTEIN COMPLEXES; PROTON-MOTIVE FORCES; SIDE-CHAINS; TRANSFER PATHWAY; TRANSMEMBRANE HELICES; TRANSMEMBRANES; WATER CHANNELS; WATER MOLECULE;

CARBOXYLATION; LIPID BILAYERS;

MOLECULAR DYNAMICS;

ASPARTIC ACID; CARBOXYLIC ACID; GLUTAMIC ACID; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; WATER;

ARTICLE; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME SYNTHESIS; GEOMETRY; LIPID BILAYER; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTON MOTIVE FORCE; PROTON TRANSPORT; SIMULATION;

AMINO ACID SUBSTITUTION; MOLECULAR DYNAMICS SIMULATION; MUTATION, MISSENSE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTON-TRANSLOCATING ATPASES; PROTONS; WATER;

EID: 84867757591     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.398396     Document Type: Article

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