Spray-dried polymeric nanoparticles for pharmaceutics: A review of patents

Recent Patents on Drug Delivery and Formulation

Volumn 6, Issue 3, 2012, Pages 195-208

  Beck, Ruy C R ^a   Ourique, Aline F ^a   Guterres, Sílvia S ^a   Pohlmann, Adriana R ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Drug delivery; Nanocapsules; Nanoparticles; Nanospheres; Polymeric; Spray drying; Therapeutic and diagnosis

Indexed keywords

ALBENDAZOLE; ALBUMIN; ARTEMISININ; ATORVASTATIN; BECLOMETASONE DIPROPIONATE; CARNOSIC ACID; CELECOXIB; CLARITHROMYCIN; CROMOGLYCATE DISODIUM; DICHLOROMETHANE; ETHYL CELLULOSE; FENBENDAZOLE; FENOFIBRATE; GLIPIZIDE; GLUTARALDEHYDE; HESPERETIN; HYDROXYPROPYLMETHYLCELLULOSE; IBUPROFEN; ITRACONAZOLE; KETOCONAZOLE; MACROGOL; NANOPARTICLE; NAPROXEN; NIFEDIPINE; POLOXAMER; POLYGLACTIN; POLYMER; RESVERATROL; TACROLIMUS; UNINDEXED DRUG;

DISPERSION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SYNTHESIS; HYDROPHILICITY; HYDROPHOBICITY; NANOEMULSION; NANOTECHNOLOGY; PARTICLE SIZE; PATENT; PHARMACEUTICS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; REVIEW; SHELF LIFE; SPRAY DRYING;

BIOLOGICAL AVAILABILITY; DRUG DELIVERY SYSTEMS; DRUG DESIGN; DRUG STABILITY; EMULSIONS; HUMANS; NANOPARTICLES; PATENTS AS TOPIC; PHARMACEUTICAL PREPARATIONS; POLYMERS; SOLUBILITY;

EID: 84867752237     PISSN: 18722113     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221112802652651     Document Type: Review

References (62)

1. Roco MC. Broader societal issues of nanotechnology. J Nanoparticle Res 2003; 5: 181-9.
2. Salamanca-Buentello F, Persad DL, Court EB, Martin DK, Daar AS, Singer PA. Nanotechnology and the developing world. Plos Med 2005; 2: 300-3.
3. Jain KK. Nanotechnology in clinical laboratory diagnostics. Clin Chim Acta 2005; 358: 37-54.
4. Hu Y, Fine DH, Tasciotti E, Bouamrani A, Ferrari M. Nanodevices in diagnostics. Nanomed Nanobiotechnol 2011; 3: 11-32.
5. Torchilin VP. Targeted pharmaceutical nanocarriers for cancer therapy and imaging. AAPS Journal 2007; 9: 128-47.
6. Baroli B. Penetration of nanoparticles and nanomaterials in the skin: Fiction or reality? J Pharm Sci 2010; 99: 21-50.
7. Kingsley JD, Dou H, Morehead J, Rabinow B, Gendelman HE, Destache CJ. Nanotechnology: A focus on nanoparticles as a drug delivery system. J Neuroimmune Pharmacol 2006; 1: 340-50.
8. Masareddy RS, Sutar RS, Yellanki SK. Nano drug delivery systems-a review. IJPSR 2011; 2: 203-16.
9. Schaffazick SR, Pohlmann AR, Dalla-Costa T, Guterres SS. Freeze-drying polymeric colloidal suspensions: Nanocapsules, nanospheres and nanodispersion. A comparative study. Eur J Pharm Bipharm 2003; 56: 501-5.
10. Müller CR, Bassani VL, Pohlmann AR, Michalowski CB, Petrovick PR, Guterres SS. Preparation and characterization of spraydried polymeric nanocapsules. Drug Dev Ind Pharm 2000; 26: 343-7.
11. Friedrich RB, Fontana MC, Bastos MO, Pohlmann AR, Guterres SS, Beck RCR. Drying polymeric drug-loaded nanocapsules: The wet granulation process as a promising approach. J Nanosci Nanotechnol 2010; 10: 616-21.
12. Tewa-Tagne P, Briançon S, Fessi H. Preparation of redispersible dry nanocapsules by means of spray-drying: Development and characterization. Eur J Pharm Sci 2007; 30: 124-35.
13. Vehring R. Pharmaceutical particle engineering via spray drying. Pharmaceut Res 2008; 25: 999-1022.
14. Krzysztof S, Krzysztof C. Spray drying technique: II. Current applications in pharmaceutical technology. J Pharm Sci 2010; 99: 587-97.
15. Kalombo, L. Nanoparticle carriers for drug administration and process for producing same. WO2009105792 (2009).
16. Christensen KL, Pedersen GP, Kristensen HG. Preparation of redispersible dry emulsions by spray drying. Int J Pharm 2001; 212: 187-94.
17. Goldbach P, Brochart H, Stamm A. Spray-drying of liposomes for a pulmonary administration. I. Chemical stability of phospholipids. Drug Dev Ind Pharm 1993; 19: 2611-22.
18. Kwok PCL, Tunsirikongkon A, Glover W, Chan H. Formation of protein nano-matrix particles with controlled surface architecture for respiratory drug delivery. Pharm Res 2011; 28: 788-96.
19. Pohlmann AR, Cruz L, Mezzalira G, Soares LU, Silveira NP, Guterres SS. Structural model of polymeric nanospheres containing indomethacin ethyl ester and in vivo antiedematogenic activity. Int J Nanotechnol 2007; 4: 454-67.
20. Mora-Huertas CE, Fessi H, Elaissari A. Polymer-based nanocapsules for drug delivery. Int J Pharm 2010; 385: 113-42.
21. Mohanraj VJ, Chen Y. Nanoparticles-A review. Trop J Pharm Res 2006; 5: 561-73.
22. Choi J, Yoo JY, Kwak H, Nam BU, Lee J. Role of polymeric stabilizers for drug nanocrystal dispersions. Curr Appl Phys 2005; 5: 472-4.
23. Selvaraj, U., Messing, G.L. Synthesis of drug nanoparticles by spray drying. WO9713503 (1997).
24. Allison, D.S., Schmidt, P.G., Hudnut, P.S. Controlled release compositions of estradiol metabolites. WO03092585 (2003).
25. D'Souza, M.J. Nanospheres encapsulating bioactive material and method for formulation of nanospheres. WO2010037142 (2010).
26. Marx, G., Gorodetsky, R. Fibrin nanoparticles and uses thereof. US20030045690 (2003).
27. Temtsin, K.G., Averbuch, M., Gitis, L., Zelkind, I. Compositions comprising lipophilic active compounds and method for their preparation. WO2009040818 (2009).
28. Li X, Anton N, Arpagus C, Belleteix F, Vandamme TF. Nanoparticles by spray drying using innovative new technology: The Büchi Nano Spray Dryer B-90. J Control Release 2010; 147: 304-10.
29. Müller, B.W., Rasenack, N. Method for the production and the use of microparticles and nanoparticles by constructive micronisation. WO03080034 (2003).
30. Müller, B.W., Rasenack, N. Method for the production and the use of microparticles and nanoparticles by constructive micronisation. US20050139144 (2005).
31. Jain, R.A., Ruddy, S.B., Cumming, K.I., Clancy, M.J.A., Codd, J.E. Rapidly desintegrating solid oral dosage form. US20040057993 (2004).
32. Bosch, H.W., Ryde, N.P. Novel glipizide compositions. US20050019412 (2005).
33. Magdassi, S., Netivi, H., Goshen, K. Organic nanoparticles obtained from microemulsions by solvent evaporation. WO2008032327 (2008).
34. Magdassi, S., Netivi, H., Goshen, K. Organic nanoparticles obtained from microemulsions by solvent evaporation. US20110021592 (2011).
35. Duncalf, D.J., Essa, A.H., Foster, A.J., Long, J., Rannard, S.P., Wang, D. Improvements relating to anti-parasitic compositions. WO2008006713 (2008).
36. Poletto FS, Fiel LA, Donida B, Ré MI, Guterres SS, Pohlmann AR. Controlling the size of poly(hydroxybutyrate-co-hydroxyvalerate) nanoparticles prepared by emulsification-diffusion technique using ethanol as surface agent. Colloid Surface A 2008; 324: 105-12.
37. Poletto FS, Silveira RP, Fiel LA, Donida B, Rizzi M, Guterres SS et al. Size-control of poly(ε-caprolactone) nanospheres by the interface effect of ethanol on the primary emulsion droplets. J Nanosci Nanotechnol 2009; 9: 4933-41.
38. Kalombo, L. Nanoparticle carriers for drug administration and process for producing same. US20110033550 (2011).
39. Guterres, S.S., Pohlmann, A. R., Dalla Costa, T., Bassani, V., Müller, C.R. Processo de secagem de suspensões coloidais de nanocápsulas e nanoesferas poliméricas por aspersão. BR099060817 (1999).
40. Guterres, S.S., Muller, C.R., Bassani V.L., Pohlmann, A.R., Dalla Costa, T.C.T. Procede de sechage de suspensions colloidales de nanocapsules et de nanospheres polymeres par aspersion. FR2801227 (2001).
41. Guterres SS, Beck RCR, Pohlmann AR. Spray-drying technique to prepare innovative nanoparticulated formulations for drug administration: a brief overview. Braz J Phys 2009; 39: 205-9.
42. Suzuki, H.J., Alario, D.J. Solid pharmaceutical composition comprising agglomerate nanoparticles and a process for producing the same. WO2007053923 (2007).
43. Suzuki, H.J., Alario, D.J. Solid pharmaceutical composition comprising agglomerate nanoparticles and a process for producing the same. US20110052652 (2011).
44. Bosch, H.W., Ostrander, K.D., Cooper, E.R. Aerosols comprising nanoparticle drugs. WO0027363 (2000).
45. Benita, S., Rom, A., Nasser, T. Delivery system for active agents. WO2007083316 (2007).
46. Benita, S., Rom, A., Nasser, T. Microspheres comprising nanocapsules containing a lipophilic drug. US20090011009 (2009).
47. Shefer, A., Shefer, S.D. Targeted controlled delivery compositions activated by changes in pH or salt concentration. US20030195133 (2003).
48. Shefer, A., Shefer, S.D. pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients. US20040109894 (2004).
49. Shefer, A., Shefer, S. Multicomponent biodegradable bioadhesive controlled release system for oral care products. WO0245575 (2002).
50. Sengupta, S., Zhao, G., Capila, I., Eavarone, D., Sasisekharan, R. Nanocell drug delivery system. WO2005084710 (2005).
51. Sengupta, S., Sasisekharan, R., Bosques, C.J. Nanocells for diagnosis and treatment of diseases and disorders. WO2006099445 (2006).
52. Patzlaff, J., Entenmann, M., Huber, A., Schauer, T. Die folgenden Angaben sind den vom Anmelder eingereichten Unterlagen entnommen. DE102008005826 (2008).
53. Miller, W.K., Smithey, D.T., Frankamp, B.L., Tadday, R. Pharmaceutical compositions comprising nanoparticles and a resuspending material. WO2009073215 (2009).
54. Beyerinck, R.A., Bloom, C. J., Crew, M. D., Friesen, D.T., Morgen, M.M., Smithey, D.T. Pharmaceutical compositions based on A) nanoparticles comprising enteric polymers and B) casein. WO2008065502 (2008).
55. Bloom, C.J., Crew, M.D., Miller, W.K., Morgen, M.M., Smithey, D.T. Nanoparticles comprising Cox-2 inhibitors and a non-ion ionizable polymer. WO2008135829 (2008).
56. Bloom, C.J., Crew, M.D., Miller, W.K., Morgen, M.M., Smithey, D.T. Nanopartilces comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer. WO2008149192 (2008).
57. Miller, W.K. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate. WO2008149230 (2008).
58. Shen, Z., Yun, J.S.L., Hu, J., Jugade, N.A., Zhang, J., Chen, W., Wang Z., Gao, L., Glover, W., Chen, J.F. A process for making particles for delivery of drug nanoparticles. WO2010036211 (2010).
59. Beck RCR, Haas SE, Guterres SS, Ré MI, Benvenutti EV, Pohlmann AR. Nanoparticle-coated organic-inorganic microparticles: experimental design and gastrointestinal tolerance evaluation. Quim Nova 2006; 29: 990-6.
60. Magdassi, S., Spernath, L. Method for the preparation of nanoparticles from nanoemulsions. US20110135734 (2011).
61. Hossainny, S.F.A., Ludwig, F.N., Sridharan, S. Nanoparticle releasing medical devices. EP2347776 (2011).
62. Ludwig, F.N., Hossainny, S.F.A., Svensson, B., Sharkawy, A., Cima, M.J., Farokhzad, O.C., Magana, J., Von Oepen, R., Chow, M., Webler, Jr, W.E., Yribarren, T.R., Ehrenreich, K.J. Magnetically sensitive drug carriers and delivery devices. US20110196187 (2011).