Do you need to definitively diagnose the location of a pregnancy of unknown location? the case for "yes"

Fertility and Sterility

Volumn 98, Issue 5, 2012, Pages 1078-1084

  Rubal, Lauren ^a   Chung, Karine ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

dilation and currettage; ectopic pregnancy; methotrexate; Pregnancy of unknown location; spontaneous abortion

Indexed keywords

CHORIONIC GONADOTROPIN; METHOTREXATE;

ARTICLE; CURETTAGE; DIAGNOSTIC ERROR; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; ECTOPIC PREGNANCY; EMBRYOPATHY; FETUS MALFORMATION; HUMAN; LOW BIRTH WEIGHT; LOW DRUG DOSE; NONHUMAN; OVARIAN RESERVE; PATIENT COUNSELING; PREGNANCY DISORDER; PREGNANCY OF UNKNOWN LOCATION; PREMATURE LABOR; PRIORITY JOURNAL; PROGNOSIS; SINGLE DRUG DOSE; SMALL FOR DATE INFANT; SPONTANEOUS ABORTION; TREATMENT INDICATION;

EID: 84867728778     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2012.09.033     Document Type: Review

References (58)

1. K.T. Barnhart Clinical practice. Ectopic pregnancy N Engl J Med 361 2009 379 387
2. G. Condous, E. Kirk, C. Lu, S. Van Huffel, O. Gevaert, B. De Moor, F. De Smet, D. Timmerman, and T. Bourne Diagnostic accuracy of varying discriminatory zones for the prediction of ectopic pregnancy in women with a pregnancy of unknown location Ultrasound Obstet Gynecol 26 2005 770 775
3. K.T. Barnhart, H. Simhan, and S.A. Kamelle Diagnostic accuracy of ultrasound above and below the beta-hCG discriminatory zone Obstet Gynecol 94 1999 583 587
4. K. Barnhart, N.M. van Mello, T. Bourne, E. Kirk, B. Van Calster, and C. Bottomley Pregnancy of unknown location: a consensus statement of nomenclature, definitions, and outcome Fertil Steril 95 2011 857 866
5. S.D. Spandorfer, A.W. Menzin, K.T. Barnhart, V.A. LiVolsi, and S.M. Pfeifer Efficacy of frozen-section evaluation of uterine curettings in the diagnosis of ectopic pregnancy Am J Obstet Gynecol 175 1996 603 605
6. R.J. Stock, and A. Kanbour Prehysterectomy curettage Obstet Gynecol 45 1975 537 541
7. J.A. Rock, and H.W. Jones Te Linde's operative gynecology 10th ed. 2008 Lippincott Williams & Wilkins Philadelphia
8. M. Niinimäki, P. Jouppila, H. Martikainen, and A. Talvensaari-Mattila A randomized study comparing efficacy and patient satisfaction in medical or surgical treatment of miscarriage Fertil Steril 86 2006 367 372
9. J. Zhang, J.M. Gilles, K. Barnhart, M.D. Creinin, C. Westhoff, and M.M. Frederick A comparison of medical management with misoprostol and surgical management for early pregnancy failure N Engl J Med 353 2005 761 769
10. K.T. Barnhart, C.R. Gracia, B. Reindl, and J.E. Wheeler Usefulness of pipelle endometrial biopsy in the diagnosis of women at risk for ectopic pregnancy Am J Obstet Gynecol 188 2003 906 909
11. M.A. Fritz, and L. Speroff Ectopic pregnancy M.A. Fritz, L. Speroff, Clinical gynecologic endocrinology and infertility 8th ed. 2011 Lippincott Williams & Wilkins Philadelphia 1388 1396
12. T. Bignardi, G. Condous, E. Kirk, B. Van Calster, S. Van Huffel, D. Timmerman, and T. Bourne Viability of intrauterine pregnancy in women with pregnancy of unknown location: prediction using human chorionic gonadotropin ratio vs. progesterone Ultrasound Obstet Gynecol 35 2010 656 661
13. K.T. Barnhart, I. Katz, A. Hummel, and C.R. Gracia Presumed diagnosis of ectopic pregnancy Obstet Gynecol 100 2002 505 510
14. A. Shaunik, J. Kulp, D.H. Appleby, M.D. Sammel, and K.T. Barnhart Utility of dilation and curettage in the diagnosis of pregnancy of unknown location Am J Obstet Gynecol 204 2011 130.e1 130.e6
15. K. Chung, U. Chandavarkar, N. Opper, and K. Barnhart Reevaluating the role of dilation and curettage in the diagnosis of pregnancy of unknown location Fertil Steril 96 2011 659 662
16. S. Banerjee, N. Aslam, N. Zosmer, B. Woelfer, and D. Jurkovic The expectant management of women with early pregnancy of unknown location Ultrasound Obstet Gynecol 14 1999 231 236
17. D. Trio, N. Strobelt, C. Picciolo, R.H. Lapinski, and A. Ghidini Prognostic factors for successful expectant management of ectopic pregnancy Fertil Steril 63 1995 469 472
18. J. Korhonen, U.H. Stenman, and P. Ylöstalo Serum human chorionic gonadotropin dynamics during spontaneous resolution of ectopic pregnancy Fertil Steril 61 1994 632 636
19. I.Z. MacKenzie, and J.G. Bibby Critical assessment of dilatation and curettage in 1029 women Lancet 2 1978 566 568
20. L. Nurmohamed, M. Moretti, T. Schecter, A. Einarson, D. Johnson, S. Lavigne, A. Erabara, G. Koren, and Y. Finkelstein Outcome following high-dose methotrexate in pregnancies misdiagnosed as ectopic AJOG 205 2011 533.e1 533.e3
21. S. Poggi, and A. Ghidini Importance of timing of gestational exposure to methotrexate for its teratogenic effects when used in setting of misdiagnosis of ectopic pregnancy Fert Steril 96 2011 669 671
22. M. Addar Methotrexate embryopathy in a surviving intrauterine fetus after presumed diagnosis of ectopic pregnancy: case report J Obstet Gynaecol Can 26 2004 1001 1003
23. C. Nguyen, A. Duhl, C. Escallon, and K. Blakemore Multiple anomalies in a fetus exposed to low-dose methotrexate in the first trimester Obstet Gynecol 99 2002 599 602
24. J. Corona-Rivera, A. Rea-Rosas, A. Santana-Ramirez, J. Acosta-Leon, J. Hernandez-Rocha, and K. Miguel-Jimenez Holoprosencephaly and genitourinary anomalies in fetal methotrexate syndrome Am J Med Genet 152A 2010 1741 1746
25. K. Piggott, A. Sorbello, E. Riddle, and W. DeCampli Congenital cardiac defects: a possible association of aminopterin syndrome and in utero methotrexate exposure? Pediatr Cardiol 32 2011 518 520
26. M. Feldkamp, and J. Carey Clinical teratology counseling and consultation case report: low dose methotrexate exposure in the early weeks of pregnancy Teratology 47 1993 533 539
27. A.E. Donnenfield Methotrexate exposure prior and during pregnancy Teratology 49 1994 79 81
28. M.E. Lloyd, M. Carr, P. McElhatton, G.M. Hall, and R.A. Hughes The effects of methotrexate on pregnancy, fertility and lactation Q J Med 92 1999 551 563
29. J.A. Martinez Lopez, E. Loza, and L. Carmona Systematic review on the safety of methotrexate in rheumatoid arthritis regarding the reproductive system (fertility, pregnancy, and breastfeeding) Clin Exp Rheumatol 27 2009 678 684
30. W.A. Bleyer Methotrexate: clinical pharmacology, current status and therapeutic guidelines Cancer Treatment Reviews 4 1977 87 101
31. D.H. Huffman, S.H. Wan, D.L. Azarnoff, and B. Hogstraten Pharmacokinetics of methotrexate Clin Pharmacol Ther 14 1973 572 579
32. R.G. Stoller, K.R. Hande, S.A. Jacobs, S.A. Rosenberg, and B.A. Chabner Use of plasma pharmacokinetics to predict and prevent methotrexate toxicity N Engl J Med 297 1977 630 634
33. P.R. Leme, P.J. Creaven, L.M. Allen, and M. Berman Kinetic model for the disposition and metabolism of moderate and high-dose methotrexate (NSC-740) in man Cancer Chemother Rep 59 1975 811 817
34. B. Bannwarth, F. Péhourcq, T. Schaeverbeke, and J. Dehais Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis Clin Pharmacokinet 30 1996 194 210
35. K. Barnhart, C. Coutifaris, and M. Esposito The pharmacology of methotrexate Exp Opin Pharmacother 2 2001 409 417
36. B.A. Chabner, C.J. Allegra, G.A. Curt, N.J. Clendeninn, J. Baram, and S. Koizumi Polyglutamation of methotrexate. Is methotrexate a prodrug? J Clin Invest 76 1985 907 912
37. R. Hackmon, S. Sakaguchi, and G. Koren Effect of methotrexate treatment of ectopic pregnancy on subsequent pregnancy Can Fam Physician 57 2011 37 39
38. J.M. Dalrymple, L.K. Stamp, J.L. O'Donnell, P.T. Chapman, M. Zhang, and M.L. Barclay Pharmacokinetics of oral methotrexate in patients with rheumatoid arthritis Arthritis Rheum 58 2008 3299 3308
39. K.K. Temprano, R. Bandlamudi, and T.L. Moore Antirheumatic drugs in pregnancy and lactation Semin Arthritis Rheum 35 2005 112 121
40. A. Makol, K. Wright, and S. Amin Rheumatoid arthritis and pregnancy: safety considerations in pharmacological management Drugs 71 2011 1973 1987
41. R. Svirsky, U. Rozovski, Z. Vaknin, M. Pansky, D. Schneider, and R. Halperin The safety of conception occurring shortly after methotrexate treatment of an ectopic pregnancy Reprod Toxicol 27 2009 85 87
42. S. Karri, and V. G Effect of methotrexate and leucovorin on female reproductive tract of albino rats Cell Biochem Funct 29 2011 1 21
43. M. Gol, U. Saygili, M. Koyuncuoglu, and T. Uslu Influence of high-dose methotrexate therapy on the primordial follicles of the mouse ovary J Obstet Gynaecol Res 35 2009 429 433
44. R. Orvieto, J. Kruchkovich, E. Zohav, and J. Rabinson Does methotrexate treatment for ectopic pregnancy influence the patient's performance during a subsequent in vitro fertilization/embryo transfer cycle? Fert Steril 88 2007 1685 1686
45. B. Oriol, A. Barrio, A. Pacheco, J. Serna, J.L. Zuzuarregui, and J.A. Garcia-Velasco Systemic methotrexate to treat ectopic pregnancy does not affect ovarian reserve Fertil Steril 90 2008 1579 1582
46. J.F. McLaren, R.O. Burney, A.A. Milki, L.M. Westphal, M.H. Dahan, and R.B. Lathi Effect of methotrexate exposure on subsequent fertility in women undergoing controlled ovarian stimulation Fertil Steril 92 2009 515 519
47. The practice committee of the American Society for Reproductive Medicine Medical treatment of ectopic pregnancy Fertil Steril 90 2008 S206 S212
48. J.D. Isaacs, R.P. McGehee, and B.D. Cowan Life-threatening neutropenia following methotrexate treatment of ectopic pregnancy: a report of two cases Obstet Gynecol 88 1996 694 696
49. M. Straka, E. Zeringue, and M. Goldman A rare drug reaction to methotrexate after treatment for ectopic pregnancy Obstet Gynecol 103 2004 1047 1048
50. A. Schoenfeld, R. Mashiach, M. Vardy, and J. Ovadia Methotrexate pneumonitis in nonsurgical treatment of ectopic pregnancy Obstet Gynecol 80 1992 520 521
51. T.J. Horrigan, J. Fanning, and M.P. Marcotte Methotrexate pneumonitis after systemic treatment for ectopic pregnancy Am J Obstet Gynecol 176 1997 714 715
52. H. Kelly, D. Harvey, and S. Moll A cautionary tale: fatal outcome of methotrexate therapy given for management of ectopic pregnancy Obstet Gynecol 107 2006 439 441
53. S.B. Teal Comment on a cautionary tale: fatal outcome of methotrexate therapy given for management of ectopic pregnancy Obstet Gynecol 107 2006 1420 1421
54. S. Chhabra, A. Chakravarty, and P. Jindal A fatal methotrexate-treated case of ectopic pregnancy with genital tuberculosis J Obstet Gynaecol 20 2000 545 546
55. A. Ego, D. Subtil, and C. Di Pompeo Patient satisfaction with management of ectopic pregnancy Eur J Obstet Gynecol Reprod Biol 98 2001 83 90
56. A. Bachelot, H. Fernandez, and N. Job-Spira [Experience of ectopic pregnancy] Contracept Fertil Sex 22 1994 478 484
57. M. Ailawadi, S.A. Lorch, and K.T. Barnhart Cost-effectiveness of presumptively medically treating women at risk for ectopic pregnancy compared with first performing a dilatation and curettage Fertil Steril 83 2005 376 382
58. Centers for Disease Control and Prevention (CDC) Ectopic pregnancy-United States, 1990-1992 MMWR Morb Mortal Wkly Rep 44 1995 46