Changes in cardiopulmonary function induced by nanoparticles

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Volumn 4, Issue 6, 2012, Pages 691-702

  Mann, Erin E ^a   Thompson, Leslie C ^a   Shannahan, Jonathan H ^a   Wingard, Christopher J ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE HEALTH EFFECTS; AERODYNAMIC SIZES; BIOLOGICAL IMPACTS; BIOMEDICAL FIELDS; BLOOD FLOW; CARDIAC ARRHYTHMIA; CARDIAC FUNCTIONS; CARDIO-PULMONARY FUNCTION; CHEMICAL COMPOSITIONS; DIRECT INTERACTIONS; ELECTRICAL ACTIVITIES; HEART RATES; HUMAN EXPOSURES; HUMAN HEALTH; ISCHEMIA/REPERFUSION; MYOCARDIAL INFARCTION; PHYSICOCHEMICAL PROPERTY; VASCULAR ENDOTHELIAL CELLS; VASCULAR TONES;

BLOOD PRESSURE; DISEASES; ENDOTHELIAL CELLS; NANOPARTICLES;

TOXICITY;

ADVANCED GLYCATION END PRODUCT RECEPTOR; CATECHOLAMINE; CERIUM OXIDE; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; IRON OXIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MULTI WALLED NANOTUBE; NANOPARTICLE; NICKEL COMPLEX; NITRIC OXIDE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; SILICON DIOXIDE; SILVER NANOPARTICLE; SINGLE WALLED NANOTUBE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; THROMBOXANE A2; TITANIUM DIOXIDE; TUMOR NECROSIS FACTOR ALPHA; ZINC OXIDE;

ARTICLE; AUTONOMIC DYSFUNCTION; BLOOD FLOW; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; CARDIOPULMONARY FUNCTION; CARDIOTOXICITY; CATECHOLAMINE RELEASE; CHEMICAL COMPOSITION; CYTOTOXICITY; ELECTRIC ACTIVITY; EXPOSURE; HEALTH HAZARD; HEART ARRHYTHMIA; HEART MUSCLE ISCHEMIA; HEART RATE; HUMAN; HYPERTENSION; INFLAMMATION; LUNG TOXICITY; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PARTICLE SIZE; PRESSORECEPTOR; PRIORITY JOURNAL; REGULATORY MECHANISM; REPERFUSION INJURY; THROMBOSIS; VASCULAR ENDOTHELIUM; VASCULAR RESISTANCE; VASCULAR SMOOTH MUSCLE;

ANIMALS; CARDIOVASCULAR DISEASES; CARDIOVASCULAR PHYSIOLOGICAL PHENOMENA; CARDIOVASCULAR SYSTEM; HUMANS; INHALATION EXPOSURE; NANOPARTICLES;

EID: 84867698123     PISSN: 19395116     EISSN: 19390041     Source Type: Journal    
DOI: 10.1002/wnan.1194     Document Type: Article

References (65)

1. Hubbs AF, Mercer RR, Benkovic SA, Harkema J, Sriram K, Schwegler-Berry D, Goravanahally MP, Nurkiewicz TR, Castranova V, Sargent LM. Nanotoxicology-a pathologist's perspective. Toxicol Pathol 2011, 39:301-324.
2. Oberdorster G, Oberdorster E, Oberdorster J. Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 2005, 113:823-839.
3. LeBlanc AJ, Moseley AM, Chen BT, Frazer D, Castranova V, Nurkiewicz TR. Nanoparticle inhalation impairs coronary microvascular reactivity via a local reactive oxygen species-dependent mechanism. Cardiovasc Toxicol 2010, 10:27-36.
4. 2 nanoparticle inhalation: nanotoxicity has susceptible population. Environ Sci Technol 2008, 42:8985-8992.
5. Brook RD, Rajagopalan S, Pope CA, III. Brook JR. Bhatnagar A, Ez-Roux AV, Holguin F, Hong Y, Luepker RV, Mittleman MA, et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association. Circulation 2010, 121:2331-2378.
6. Carvalho TC, Peters JI, Williams RO, III. Influence of particle size on regional lung deposition-what evidence is there? Int J Pharm 2011, 406:1-10.
7. Downs TR, Crosby ME, Hu T, Kumar S, Sullivan A, Sarlo K, Reeder B, Lynch M, Wagner M, Mills T, et al. Silica nanoparticles administered at the maximum tolerated dose induce genotoxic effects through an inflammatory reaction while gold nanoparticles do not. Mutat Res 2012, 745:38-50.
8. Cho WS, Duffin R, Poland CA, Howie SE, MacNee W, Bradley M, Megson IL, Donaldson K. Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing. Environ Health Perspect 2010, 118:1699-1706.
9. Li JJ, Muralikrishnan S, Ng CT, Yung LY, Bay BH. Nanoparticle-induced pulmonary toxicity. Exp Biol Med (Maywood) 2010, 235:1025-1033.
10. Bonner JC. Nanoparticles as a potential cause of pleural and interstitial lung disease. Proc Am Thorac Soc 2010, 7:138-141.
11. Yazdi AS, Guarda G, Riteau N, Drexler SK, Tardivel A, Couillin I, Tschopp J. Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β. Proc Natl Acad Sci U S A 2010, 107:19449-19454.
12. Ma JY, Zhao H, Mercer RR, Barger M, Rao M, Meighan T, Schwegler-Berry D, Castranova V, Ma JK. Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats. Nanotoxicology 2011, 5:312-325.
13. Horie M, Fukui H, Nishio K, Endoh S, Kato H, Fujita K, Miyauchi A, Nakamura A, Shichiri M, Ishida N, et al. Evaluation of acute oxidative stress induced by NiO nanoparticles in vivo and in vitro. J Occup Health 2011, 53:64-74.
14. Wang X, Xia T, Addo NS, Ji Z, Lin S, Meng H, Chung CH, George S, Zhang H, Wang M, et al. Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung. ACS Nano 2011, 5:9772-9787.
15. Wang X, Katwa P, Podila R, Chen P, Ke PC, Rao AM, Walters DM, Wingard CJ, Brown JM. Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice. Part Fibre Toxicol 2011, 8:24.
16. Wang L, Wang L, Ding W, Zhang F. Acute toxicity of ferric oxide and zinc oxide nanoparticles in rats. J Nanosci Nanotechnol 2010, 10:8617-8624.
17. Bourdon JA, Halappanavar S, Saber AT, Jacobsen NR, Williams A, Wallin H, Vogel U, Yauk CL. Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response and alterations in lipid homeostasis. Toxicol Sci 2012, 127:474-484.
18. Utell MJ, Frampton MW, Zareba W, Devlin RB, Cascio WE. Cardiovascular effects associated with air pollution: potential mechanisms and methods of testing. Inhal Toxicol 2002, 14:1231-1247.
19. Brook RD. Cardiovascular effects of air pollution. Clin Sci (Lond) 2008, 115:175-187.
20. Shannahan JH, Kodavanti UP, Brown JM. Manu factured and airborne nanoparticle cardiopulmonary interactions: a review of mechanisms and the possible contribution of mast cells. Inhal Toxicol 2012, 24:320-339.
21. Cho M, Cho WS, Choi M, Kim SJ, Han BS, Kim SH, Kim HO, Sheen YY, Jeong J. The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles. Toxicol Lett 2009, 189:177-183.
22. Al FA, Fauvelle F, Luciani N, Lacroix G, Levy M, Cremillieux Y, Canet-Soulas E. In vivo biodistribution and biological impact of injected carbon nanotubes using magnetic resonance techniques. Int J Nanomed 2011, 6:351-361.
23. Hahn A, Fuhlrott J, Loos A, Barcikowski S. Cytotoxicity and ion release of alloy nanoparticles. J Nanopart Res 2012, 14:1-10.
24. Oberdorster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, Cox C. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J Toxicol Environ Health A 2002, 65:1531-1543.
25. Sung JH, Ji JH, Park JD, Song MY, Song KS, Ryu HR, Yoon JU, Jeon KS, Jeong J, Han BS, et al. Subchronic inhalation toxicity of gold nanoparticles. Part Fibre Toxicol 2011, 8:16.
26. Geraets L, Oomen AG, Schroeter JD, Coleman VA, Cassee FR. Tissue distribution of inhaled micro- and nano-sized cerium oxide particles in rats: results from a 28-day exposure study. Toxicol Sci 2012, 127:463-473.
27. Semmler-Behnke M, Kreyling WG, Lipka J, Fertsch S, Wenk A, Takenaka S, Schmid G, Brandau W. Biodistribution of 1.4- and 18-nm gold particles in rats. Small 2008, 4:2108-2111.
28. Geys J, Nemmar A, Verbeken E, Smolders E, Ratoi M, Hoylaerts MF, Nemery B, Hoet PH. Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge. Environ Health Perspect 2008, 116:1607-1613.
29. Choi HS, Ashitate Y, Lee JH, Kim SH, Matsui A, Insin N, Bawendi MG, Semmler-Behnke M, Frangioni JV, Tsuda A. Rapid translocation of nanoparticles from the lung airspaces to the body. Nat Biotechnol 2010, 28:1300-1303.
30. Legramante JM, Valentini F, Magrini A, Palleschi G, Sacco S, Iavicoli I, Pallante M, Moscone D, Galante A, Bergamaschi E, et al. Cardiac autonomic regulation after lung exposure to carbon nanotubes. Hum Exp Toxicol 2009, 28:369-375.
31. Godleski JJ, Verrier RL, Koutrakis P, Catalano P, Coull B, Reinisch U, Lovett EG, Lawrence J, Murthy GG, Wolfson JM, et al. Mechanisms of morbidity and mortality from exposure to ambient air particles. Res Rep Health Eff Inst 2000, 5-88.
32. Nemmar A, Delaunois A, Nemery B, Dessy-Doize C, Beckers JF, Sulon J, Gustin P. Inflammatory effect of intratracheal instillation of ultrafine particles in the rabbit: role of C-fiber and mast cells. Toxicol Appl Pharmacol 1999, 160:250-261.
33. Donaldson K, Brown D, Clouter A, Duffin R, MacNee W, Renwick L, Tran L, Stone V. The pulmonary toxicology of ultrafine particles. J Aerosol Med 2002, 15:213-220.
34. Niwa Y, Hiura Y, Sawamura H, Iwai N. Inhalation exposure to carbon black induces inflammatory response in rats. Circ J 2008, 72:144-149.
35. Aird WC. Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ Res 2007, 100:158-173.
36. Hickey MJ, Kubes P. Intravascular immunity: the host-pathogen encounter in blood vessels. Nat Rev Immunol 2009, 9:364-375.
37. Pacurari M, Qian Y, Fu W, Schwegler-Berry D, Ding M, Castranova V, Guo NL. Cell permeability, migration, and reactive oxygen species induced by multiwalled carbon nanotubes in human microvascular endothelial cells. J Toxicol Environ Health A 2012, 75:112-128.
38. Guo YY, Zhang J, Zheng YF, Yang J, Zhu XQ. Cytotoxic and genotoxic effects of multi-wall carbon nanotubes on human umbilical vein endothelial cells in vitro. Mutat Res 2011, 721:184-191.
39. Trickler WJ, Lantz SM, Murdock RC, Schrand AM, Robinson BL, Newport GD, Schlager JJ, Oldenburg SJ, Paule MG, Slikker W, Jr, et al. Silver nanoparticle induced blood-brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cells. Toxicol Sci 2010, 118:160-170.
40. Ragaseema VM, Unnikrishnan S, Kalliyana KV, Krish nan LK. The antithrombotic and antimicrobial properties of PEG-protected silver nanoparticle coated surfaces. Biomaterials 2012, 33:3083-3092.
41. Madhavan RV, Rosemary MJ, Nandkumar MA, Krishnan KV, Krishnan LK. Silver nanoparticle impregnated poly (varepsilon-caprolactone) scaffolds: optimization of antimicrobial and noncytotoxic concentrations. Tissue Eng Part A 2011, 17:439-449.
42. Buyukhatipoglu K, Clyne AM. Superparamagnetic iron oxide nanoparticles change endothelial cell morphology and mechanics via reactive oxygen species formation. J Biomed Mater Res A 2011, 96:186-195.
43. Stapleton PA, Minarchick VC, McCawley M, Knuckles TL, Nurkiewicz TR. Xenobiotic particle exposure and microvascular endpoints: a call to arms. Microcirculation 2012, 19:126-142.
44. Pryshchep O, Ma-Krupa W, Younge BR, Goronzy JJ, Weyand CM. Vessel-specific Toll-like receptor profiles in human medium and large arteries. Circulation 2008, 118:1276-1284.
45. Dileepan KN, Stechschulte DJ. Endothelial cell activation by mast cell mediators. Methods Mol Biol 2006, 315:275-294.
46. Doyle MP, Linden J, Duling BR. Nucleoside-induced arteriolar constriction: a mast cell-dependent response. Am J Physiol 1994, 266:H2042-H2050.
47. Wingard CJ, Walters DM, Cathey BL, Hilderbrand SC, Katwa P, Lin S, Ke PC, Podila R, Rao A, Lust RM, et al. Mast cells contribute to altered vascular reactivity and ischemia-reperfusion injury following cerium oxide nanoparticle instillation. Nanotoxicology 2011, 5:531-545.
48. Vesterdal LK, Folkmann JK, Jacobsen NR, Sheykhzade M, Wallin H, Loft S, Moller P. Pulmonary exposure to carbon black nanoparticles and vascular effects. Part Fibre Toxicol 2010, 7:33.
49. Courtois A, Andujar P, Ladeiro Y, Ducret T, Rogerieux F, Lacroix G, Baudrimont I, Guibert C, Roux E, Canal-Raffin M, et al. Effect of engineered nanoparticles on vasomotor responses in rat intrapulmonary artery. Toxicol Appl Pharmacol 2010, 245:203-210.
50. Cuevas AK, Liberda EN, Gillespie PA, Allina J, Chen LC. Inhaled nickel nanoparticles alter vascular reactivity in C57BL/6 mice. Inhal Toxicol 2010, 22(Suppl 2):100-106.
51. Nurkiewicz TR, Porter DW, Hubbs AF, Stone S, Chen BT, Frazer DG, Boegehold MA, Castranova V. Pulmonary nanoparticle exposure disrupts systemic microvascular nitric oxide signaling. Toxicol Sci 2009, 110:191-203.
52. Knuckles TL, Yi J, Frazer DG, Leonard HD, Chen BT, Castranova V, Nurkiewicz TR. Nanoparticle inhalation alters systemic arteriolar vasoreactivity through sympathetic and cyclooxygenase-mediated pathways. Nanotoxicology 2011. doi:10.319/17435390.2011. 606926.
53. Stampfl A, Maier M, Radykewicz R, Reitmeir P, Gottlicher M, Niessner R. Langendorff heart: a model system to study cardiovascular effects of engineered nanoparticles. ACS Nano 2011, 5:5345-5353.
54. Tong H, McGee JK, Saxena RK, Kodavanti UP, Devlin RB, Gilmour MI. Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice. Toxicol Appl Pharmacol 2009, 239:224-232.
55. Lanfranchi PA, Somers VK. Arterial baroreflex function and cardiovascular variability: interactions and implications. Am J Physiol Regul Integr Comp Physiol 2002, 283:R815-R826.
56. Liu L, Chen B, Teng F, Shi L, Jing N, Wang L, Chen N, Xia G, Li X. Effect of Fe(3)O(4)-magnetic nanoparticles on acute exercise enhanced KCNQ(1) expression in mouse cardiac muscle. Int J Nanomed 2010, 5:109-116.
57. Niu J, Wang K, Kolattukudy PE. Cerium oxide nanoparticles inhibit oxidative stress and nuclear factor-κB activation in H9c2 cardiomyocytes exposed to cigarette smoke extract. J Pharmacol Exp Ther 2011, 338:53-61.
58. Jawad H, Boccaccini AR, Ali NN, Harding SE. Assessment of cellular toxicity of TiO2 nanoparticles for cardiac tissue engineering applications. Nanotoxicology 2011, 5:372-380.
59. Murthy SK. Nanoparticles in modern medicine: state of the art and future challenges. Int J Nanomed 2007, 2:129-141.
60. Szelenyi I. Nanomedicine: evolutionary and revolutionary developments in the treatment of certain inflammatory diseases. Inflamm Res 2012, 61:1-9.
61. Wang AZ, Langer R, Farokhzad OC. Nanoparticle delivery of cancer drugs. Annu Rev Med 2012, 63:185-198.
62. Zhang L, Gu FX, Chan JM, Wang AZ, Langer RS, Farokhzad OC. Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther 2008, 83:761-769.
63. Prijic S, Sersa G. Magnetic nanoparticles as targeted delivery systems in oncology. Radiol Oncol 2011, 45:1-16.
64. Xanthos T, Chatzigeorgiou M, Johnson EO, Chalkias A. Magnetically targeted drug delivery during cardiopulmonary resuscitation and the post-resuscitation period. Resuscitation 2012, 83:803-805.
65. Zolnik BS, Gonzalez-Fernandez A, Sadrieh N, Dobrovolskaia MA. Nanoparticles and the immune system. Endocrinology 2010, 151:458-465.