Pseudomonas aeruginosa Keratitis in Mice: Effects of Topical Bacteriophage KPP12 Administration

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Fukuda, Ken ^a   Ishida, Waka ^a   Uchiyama, Jumpei ^a   Rashel, Mohammad ^a   Kato, Shin ichiro ^b   Morita, Tamae ^c   Muraoka, Asako ^d   Sumi, Tamaki ^a   Matsuzaki, Shigenobu ^a   Daibata, Masanori ^a   Fukushima, Atsuki ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b KOCHI UNIVERSITY   (Japan)

^c KOCHI MEDICAL SCHOOL HOSPITAL   (Japan)

^d Kochi Gakuen Junior College   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; KPP 12; MYELOPEROXIDASE; PEROXIDASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL STRAIN; BACTERIOPHAGE; COLONY FORMING UNIT; CONTROLLED STUDY; CORNEA PERFORATION; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; ENZYME ASSAY; FEMALE; GENE SEQUENCE; HOST RANGE; KERATITIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; PSEUDOMONAS AERUGINOSA; SINGLE DRUG DOSE; ULTRACENTRIFUGATION;

ADMINISTRATION, TOPICAL; ANIMALS; BACTERIAL LOAD; BACTERIOPHAGES; CORNEA; DISEASE PROGRESSION; EYE INFECTIONS, BACTERIAL; FEMALE; KERATITIS; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 84867660703     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047742     Document Type: Article

References (30)

1. D'Herelle F, (1917) Sur un microbe invisible antagoniste des bacilles dysentériques. CR Acad Sci Paris 165: 373-375.
2. Duckworth DH, (1976) "Who discovered bacteriophage?". Bacteriological reviews 40: 793-802.
3. Merril CR, Scholl D, Adhya SL, (2003) The prospect for bacteriophage therapy in Western medicine. Nat Rev Drug Discov 2: 489-497.
4. Matsuzaki S, Yasuda M, Nishikawa H, Kuroda M, Ujihara T, et al. (2003) Experimental protection of mice against lethal Staphylococcus aureus infection by novel bacteriophage phi MR11. J Infect Dis 187: 613-624.
5. Wang J, Hu B, Xu M, Yan Q, Liu S, et al. (2006) Use of bacteriophage in the treatment of experimental animal bacteremia from imipenem-resistant Pseudomonas aeruginosa. Int J Mol Med 17: 309-317.
6. Wang J, Hu B, Xu M, Yan Q, Liu S, et al. (2006) Therapeutic effectiveness of bacteriophages in the rescue of mice with extended spectrum beta-lactamase-producing Escherichia coli bacteremia. Int J Mol Med 17: 347-355.
7. Biswas B, Adhya S, Washart P, Paul B, Trostel AN, et al. (2002) Bacteriophage therapy rescues mice bacteremic from a clinical isolate of vancomycin-resistant Enterococcus faecium. Infect Immun 70: 204-210.
8. Slopek S, Weber-Dabrowska B, Dabrowski M, Kucharewicz-Krukowska A, (1987) Results of bacteriophage treatment of suppurative bacterial infections in the years 1981-1986. Arch Immunol Ther Exp (Warsz) 35: 569-583.
9. Sulakvelidze A, Kutte E (2004) Bacteriophage therapy in humans. In: Kutter E, Sulakvelidze A, editors. Bacteriophages: Biology and Application: CRC Press. 381-436.
10. Weber-Dabrowska B, Mulczyk M, Gorski A, (2000) Bacteriophage therapy of bacterial infections: an update of our institute's experience. Arch Immunol Ther Exp (Warsz) 48: 547-551.
11. Proskurov VA, (1970) [Treatment of staphylococcal diseases of the eye]. Vestn Oftalmol 6: 82-83.
12. Willcox MD, (2007) Pseudomonas aeruginosa infection and inflammation during contact lens wear: a review. Optom Vis Sci 84: 273-278.
13. Khosravi AD, Mehdinejad M, Heidari M, (2007) Bacteriological findings in patients with ocular infection and antibiotic susceptibility patterns of isolated pathogens. Singapore Med J 48: 741-743.
14. Willcox MD, (2011) Review of resistance of ocular isolates of Pseudomonas aeruginosa and staphylococci from keratitis to ciprofloxacin, gentamicin and cephalosporins. Clin Exp Optom 94: 161-168.
15. Hyatt D, Chen GL, Locascio PF, Land ML, Larimer FW, et al. (2010) Prodigal: prokaryotic gene recognition and translation initiation site identification. BMC Bioinformatics 11: 119.
16. Lowe TM, Eddy SR, (1997) tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res 25: 955-964.
17. Wu M, McClellan SA, Barrett RP, Hazlett LD, (2009) Beta-defensin-2 promotes resistance against infection with P. aeruginosa. J Immunol 182: 1609-1616.
18. Hazlett LD, McClellan S, Kwon B, Barrett R, (2000) Increased severity of Pseudomonas aeruginosa corneal infection in strains of mice designated as Th1 versus Th2 responsive. Invest Ophthalmol Vis Sci 41: 805-810.
19. Williams RN, Paterson CA, Eakins KE, Bhattacherjee P, (1982) Quantification of ocular inflammation: evaluation of polymorphonuclear leucocyte infiltration by measuring myeloperoxidase activity. Curr Eye Res 2: 465-470.
20. Comeau AM, Krisch HM, (2008) The capsid of the T4 phage superfamily: the evolution, diversity, and structure of some of the most prevalent proteins in the biosphere. Mol Biol Evol 25: 1321-1332.
21. Merabishvili M, Pirnay JP, Verbeken G, Chanishvili N, Tediashvili M, et al. (2009) Quality-controlled small-scale production of a well-defined bacteriophage cocktail for use in human clinical trials. PloS one 4: e4944.
22. Carmody LA, Gill JJ, Summer EJ, Sajjan US, Gonzalez CF, et al. (2010) Efficacy of bacteriophage therapy in a model of Burkholderia cenocepacia pulmonary infection. J Infect Dis 201: 264-271.
23. Dabrowska K, Switala-Jelen K, Opolski A, Weber-Dabrowska B, Gorski A, (2005) Bacteriophage penetration in vertebrates. J Appl Microbiol 98: 7-13.
24. Fischetti VA, (2010) Bacteriophage endolysins: a novel anti-infective to control Gram-positive pathogens. International journal of medical microbiology: IJMM 300: 357-362.
25. Loeffler JM, Nelson D, Fischetti VA, (2001) Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase. Science 294: 2170-2172.
26. Nelson D, Loomis L, Fischetti VA, (2001) Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme. Proc Natl Acad Sci U S A 98: 4107-4112.
27. Sheehan MM, Garcia JL, Lopez R, Garcia P, (1997) The lytic enzyme of the pneumococcal phage Dp-1: a chimeric lysin of intergeneric origin. Mol Microbiol 25: 717-725.
28. Schuch R, Nelson D, Fischetti VA, (2002) A bacteriolytic agent that detects and kills Bacillus anthracis. Nature 418: 884-889.
29. Rashel M, Uchiyama J, Ujihara T, Uehara Y, Kuramoto S, et al. (2007) Efficient elimination of multidrug-resistant Staphylococcus aureus by cloned lysin derived from bacteriophage phi MR11. J Infect Dis 196: 1237-1247.
30. Gorski A, Targonska M, Borysowski J, Weber-Dabrowska B, (2009) The potential of phage therapy in bacterial infections of the eye. Ophthalmologica 223: 162-165.