-
1
-
-
79960337453
-
Heat shock proteins in oncology: diagnostic biomarkers or therapeutic targets?
-
Khalil A.A., Kapaby N.F., Deraz S.F., Smith C. Heat shock proteins in oncology: diagnostic biomarkers or therapeutic targets?. Biochim. Biophys. Acta 2011, 86:89-104.
-
(2011)
Biochim. Biophys. Acta
, vol.86
, pp. 89-104
-
-
Khalil, A.A.1
Kapaby, N.F.2
Deraz, S.F.3
Smith, C.4
-
2
-
-
44149104599
-
Heat shock proteins: essential proteins for apoptosis regulation
-
Lanneau D., Brunet M., Frisan E., Solary E., Fontenay M., Garrido C. Heat shock proteins: essential proteins for apoptosis regulation. J. Cell. Mol. Med. 2008, 2:743-761.
-
(2008)
J. Cell. Mol. Med.
, vol.2
, pp. 743-761
-
-
Lanneau, D.1
Brunet, M.2
Frisan, E.3
Solary, E.4
Fontenay, M.5
Garrido, C.6
-
3
-
-
3242879188
-
'The stress of dying': the role of heat shock proteins in the regulation of apoptosis
-
Beere H.M. 'The stress of dying': the role of heat shock proteins in the regulation of apoptosis. J. Cell Sci. 2004, 117:2641-2651.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 2641-2651
-
-
Beere, H.M.1
-
4
-
-
21744445069
-
Heat shock proteins in cancer: diagnostic, prognostic, predictive and treatment implications
-
Ciocca D.R., Calderwood S.K. Heat shock proteins in cancer: diagnostic, prognostic, predictive and treatment implications. Cell Stress Chaperones 2005, 10:86-103.
-
(2005)
Cell Stress Chaperones
, vol.10
, pp. 86-103
-
-
Ciocca, D.R.1
Calderwood, S.K.2
-
5
-
-
33644835965
-
Heat shock proteins in cancer: chaperones of tumorigenesis
-
Calderwood S.K., Khaleque M.A., Sawyer D.B., Ciocca D.R. Heat shock proteins in cancer: chaperones of tumorigenesis. Trends Biochem. Sci. 2006, 31:164-172.
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 164-172
-
-
Calderwood, S.K.1
Khaleque, M.A.2
Sawyer, D.B.3
Ciocca, D.R.4
-
6
-
-
62349088789
-
Apoptosis versus cell differentiation: role of heat shock proteins HSP90, HSP70 and HSP27
-
Lanneau D., de Thonel A., Maurel S., Didelot C., Garrido C. Apoptosis versus cell differentiation: role of heat shock proteins HSP90, HSP70 and HSP27. Prion 2007, 1:53-60.
-
(2007)
Prion
, vol.1
, pp. 53-60
-
-
Lanneau, D.1
de Thonel, A.2
Maurel, S.3
Didelot, C.4
Garrido, C.5
-
7
-
-
77956933047
-
Heat shock proteins in breast cancer progression - a suitable case for treatment
-
Calderwood S.K. Heat shock proteins in breast cancer progression - a suitable case for treatment. Int. J. Hyperthermia 2010, 26:68-685.
-
(2010)
Int. J. Hyperthermia
, vol.26
, pp. 68-685
-
-
Calderwood, S.K.1
-
8
-
-
34248195608
-
High HSP90 expression is associated with decreased survival in breast cancer
-
Pick E., Kluger Y., Giltnane J.M. High HSP90 expression is associated with decreased survival in breast cancer. Cancer Res. 2007, 67:2932-2937.
-
(2007)
Cancer Res.
, vol.67
, pp. 2932-2937
-
-
Pick, E.1
Kluger, Y.2
Giltnane, J.M.3
-
9
-
-
33846940789
-
Vincristine regulates the phosphorylation of the antiapoptotic protein HSP27 in breast cancer cells
-
Casado P., Zuazua-Villar P., del Valle E., Martínez-Campa C., Lazo P.S., Ramos S. Vincristine regulates the phosphorylation of the antiapoptotic protein HSP27 in breast cancer cells. Cancer Lett. 2007, 247:3265-32659.
-
(2007)
Cancer Lett.
, vol.247
, pp. 3265-32659
-
-
Casado, P.1
Zuazua-Villar, P.2
del Valle, E.3
Martínez-Campa, C.4
Lazo, P.S.5
Ramos, S.6
-
10
-
-
0034643424
-
HSP27 functions as negative regulator of cytochrome c-dependent activation of procaspase-3
-
Pandey P., Farber R., Nakazawa A., Kumar S., Bharti A., Nalin C., Weichselbaum R., Kufe D., Kharbanda S. HSP27 functions as negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene 2000, 19:1975-1981.
-
(2000)
Oncogene
, vol.19
, pp. 1975-1981
-
-
Pandey, P.1
Farber, R.2
Nakazawa, A.3
Kumar, S.4
Bharti, A.5
Nalin, C.6
Weichselbaum, R.7
Kufe, D.8
Kharbanda, S.9
-
11
-
-
0033796051
-
Inhibition of Daxx-mediated apoptosis by heat shock protein 27
-
Charette S.J., Lavoie J.N., Lambert H., Landry J. Inhibition of Daxx-mediated apoptosis by heat shock protein 27. Mol. Cell Biol. 2000, 20:7602-7612.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 7602-7612
-
-
Charette, S.J.1
Lavoie, J.N.2
Lambert, H.3
Landry, J.4
-
12
-
-
0036143720
-
HSP27 as a negative regulator of cytochrome c release
-
Paul C., Manero F., Gonin S., Kretz-Remy C., Virot S., Arrigo A.P. HSP27 as a negative regulator of cytochrome c release. Mol. Cell Biol. 2002, 22:816-834.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 816-834
-
-
Paul, C.1
Manero, F.2
Gonin, S.3
Kretz-Remy, C.4
Virot, S.5
Arrigo, A.P.6
-
13
-
-
0034682748
-
Heat shock protein 70 inhibits apoptosis downstream of cytochrome c release and upstream of caspase 3 activation
-
Li C.Y., Lee J.S., Ko Y.G., Kim J.I., Seo J.S. Heat shock protein 70 inhibits apoptosis downstream of cytochrome c release and upstream of caspase 3 activation. J. Biol. Chem. 2000, 275:25665-25671.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 25665-25671
-
-
Li, C.Y.1
Lee, J.S.2
Ko, Y.G.3
Kim, J.I.4
Seo, J.S.5
-
14
-
-
33845913216
-
Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy
-
Schmitt E., Gehrmann M., Brunet M., Multhoff G., Garrido C. Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy. J. Leukoc. Biol. 2007, 81:15-27.
-
(2007)
J. Leukoc. Biol.
, vol.81
, pp. 15-27
-
-
Schmitt, E.1
Gehrmann, M.2
Brunet, M.3
Multhoff, G.4
Garrido, C.5
-
15
-
-
0034253533
-
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome
-
Beere H.M., Wolf B.B., Cain K., Mosser D.D., Mahboubi A., Kuwana T., Tailor P., Morimoto R.I., Cohen G.M., Green D.R. Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome. Nat. Cell Biol. 2000, 2:469-475.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 469-475
-
-
Beere, H.M.1
Wolf, B.B.2
Cain, K.3
Mosser, D.D.4
Mahboubi, A.5
Kuwana, T.6
Tailor, P.7
Morimoto, R.I.8
Cohen, G.M.9
Green, D.R.10
-
16
-
-
7644236153
-
Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone HSP70
-
Komarova E.Y., Afanasyeva E.A., Bulatova M.M., Cheetham M.E., Margulis B.A., Guzhova I.V. Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone HSP70. Cell Stress Chaperones 2004, 9:265-275.
-
(2004)
Cell Stress Chaperones
, vol.9
, pp. 265-275
-
-
Komarova, E.Y.1
Afanasyeva, E.A.2
Bulatova, M.M.3
Cheetham, M.E.4
Margulis, B.A.5
Guzhova, I.V.6
-
17
-
-
0034117177
-
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis
-
Daugas E., Susin S.A., Zamzami N., Ferri K.F., Irinopoulou T., Larochette N., Prevost M.C., Leber B., Andrews D., Penninger J., Kroemer G. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis. FASEB J. 2000, 14:729-739.
-
(2000)
FASEB J.
, vol.14
, pp. 729-739
-
-
Daugas, E.1
Susin, S.A.2
Zamzami, N.3
Ferri, K.F.4
Irinopoulou, T.5
Larochette, N.6
Prevost, M.C.7
Leber, B.8
Andrews, D.9
Penninger, J.10
Kroemer, G.11
-
18
-
-
17944366977
-
Heat-shock protein 70 antagonizes apoptosis-inducing factor
-
Ravagnan L., Gurbuxani S., Susin S.A., Maisse C., Daugas E., Zamzami N., Mak T., Jattela M., Penninger J.M., Garrido C., Kroemer G. Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat. Cell Biol. 2001, 3:839-843.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 839-843
-
-
Ravagnan, L.1
Gurbuxani, S.2
Susin, S.A.3
Maisse, C.4
Daugas, E.5
Zamzami, N.6
Mak, T.7
Jattela, M.8
Penninger, J.M.9
Garrido, C.10
Kroemer, G.11
-
19
-
-
77954662908
-
A novel, small molecule inhibitor of HSC70/HSP70 potentiates HSP90 inhibitor induced apoptosis in HCT116 colon carcinoma cells
-
Massey A.J., Williamson D.S., Browne H., Murray J.B., Dokurno P., Shaw T., Macias A.T., Daniels Z., Geoffroy S., Dopson M., Lavan P., Matassova N., Francis G.L., Graham C.J., Parsons R., Wang Y., Padfield A., Comer M., Drysdale M.J., Wood M. A novel, small molecule inhibitor of HSC70/HSP70 potentiates HSP90 inhibitor induced apoptosis in HCT116 colon carcinoma cells. Cancer Chemother. Pharmacol. 2010, 66:535-545.
-
(2010)
Cancer Chemother. Pharmacol.
, vol.66
, pp. 535-545
-
-
Massey, A.J.1
Williamson, D.S.2
Browne, H.3
Murray, J.B.4
Dokurno, P.5
Shaw, T.6
Macias, A.T.7
Daniels, Z.8
Geoffroy, S.9
Dopson, M.10
Lavan, P.11
Matassova, N.12
Francis, G.L.13
Graham, C.J.14
Parsons, R.15
Wang, Y.16
Padfield, A.17
Comer, M.18
Drysdale, M.J.19
Wood, M.20
more..
-
20
-
-
78751478982
-
Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy
-
Rerole A.-L., Gobbo J., De Thonel A., Schmitt E., de Barros J.P.P., Hamman A., Lanneau D., Fourmaux E., Deminovi O., Micheau O., Lagrost L., Colas P., Kroemer G., Garrido C. Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy. Cancer Res. 2011, 71:484-495.
-
(2011)
Cancer Res.
, vol.71
, pp. 484-495
-
-
Rerole, A.-L.1
Gobbo, J.2
De Thonel, A.3
Schmitt, E.4
de Barros, J.P.P.5
Hamman, A.6
Lanneau, D.7
Fourmaux, E.8
Deminovi, O.9
Micheau, O.10
Lagrost, L.11
Colas, P.12
Kroemer, G.13
Garrido, C.14
-
21
-
-
67649866059
-
Heat shock protein 90 inhibitor induces apoptosis and attenuates activation of hepatic stellate cells
-
Myung S.J., Yoon J.-H., Kim B.H., Lee J.-H., Jung E.U., Lee H.-S. Heat shock protein 90 inhibitor induces apoptosis and attenuates activation of hepatic stellate cells. J. Pharmacol. Exp. Ther. 2009, 330:276-282.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.330
, pp. 276-282
-
-
Myung, S.J.1
Yoon, J.-H.2
Kim, B.H.3
Lee, J.-H.4
Jung, E.U.5
Lee, H.-S.6
-
22
-
-
33746533874
-
Heat shock protein 90: a unique chemotherapeutic target
-
Cullinan S.B., Whitesell L. Heat shock protein 90: a unique chemotherapeutic target. Semin. Oncol. 2006, 33:457-465.
-
(2006)
Semin. Oncol.
, vol.33
, pp. 457-465
-
-
Cullinan, S.B.1
Whitesell, L.2
-
23
-
-
79953700587
-
Implication of heat shock factors in tumorigenesis: therapeutical potential
-
de Thonel A., Mezger V., Garrido C. Implication of heat shock factors in tumorigenesis: therapeutical potential. Cancers 2011, 3:1158-1181.
-
(2011)
Cancers
, vol.3
, pp. 1158-1181
-
-
de Thonel, A.1
Mezger, V.2
Garrido, C.3
-
24
-
-
77951730125
-
Sulphoraphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells
-
Li Y., Zhang T., Korkaya H., Liu S., Lee H.-F., Newman B., Yu Y., Clouthier S.G., Schwartz S.J., Wicha M.S., Sun D. Sulphoraphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin. Cancer Res. 2010, 16:2580-2590.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2580-2590
-
-
Li, Y.1
Zhang, T.2
Korkaya, H.3
Liu, S.4
Lee, H.-F.5
Newman, B.6
Yu, Y.7
Clouthier, S.G.8
Schwartz, S.J.9
Wicha, M.S.10
Sun, D.11
-
25
-
-
34548445866
-
Discovery and development of sulphoraphane as a cancer chemopreventive phytochemical
-
Zhang Y., Tang L. Discovery and development of sulphoraphane as a cancer chemopreventive phytochemical. Acta Pharmacol. Sin. 2007, 28:1343-1354.
-
(2007)
Acta Pharmacol. Sin.
, vol.28
, pp. 1343-1354
-
-
Zhang, Y.1
Tang, L.2
-
26
-
-
34147135143
-
Sulphoraphane induces cell type-specific apoptosis in human breast cancer cell lines
-
Pledgie-Tracy A., Sobolewski M.D., Davidson N.E. Sulphoraphane induces cell type-specific apoptosis in human breast cancer cell lines. Mol. Cancer Ther. 2007, 6:1013-1021.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 1013-1021
-
-
Pledgie-Tracy, A.1
Sobolewski, M.D.2
Davidson, N.E.3
-
27
-
-
80054096254
-
Curcumin sensitizes the effect of chemotherapeutic drugs via modulation of protein kinase C, Telomerase, NFκB and Histone Deacetylase in breast cancer
-
Roy M., Mukherjee S., Sarkar R., Biswas J. Curcumin sensitizes the effect of chemotherapeutic drugs via modulation of protein kinase C, Telomerase, NFκB and Histone Deacetylase in breast cancer. Ther. Deliv. 2011, 2:1275-1293.
-
(2011)
Ther. Deliv.
, vol.2
, pp. 1275-1293
-
-
Roy, M.1
Mukherjee, S.2
Sarkar, R.3
Biswas, J.4
-
28
-
-
80052707191
-
Apoptosis induction in primary human colorectal cancer cell lines and retarded tumor growth in SCID mice by sulphoraphane
-
Chen M.-J., Tang W.-Y., Hsu C.-W., Tsai Y.-T., Wu J.-F., Lin C.-W., Cheng Y.-M., Hsu Y.-C. Apoptosis induction in primary human colorectal cancer cell lines and retarded tumor growth in SCID mice by sulphoraphane. Evid. Based Complement Alternat. Med. 2012, 2012:415231.
-
(2012)
Evid. Based Complement Alternat. Med.
, vol.2012
, pp. 415231
-
-
Chen, M.-J.1
Tang, W.-Y.2
Hsu, C.-W.3
Tsai, Y.-T.4
Wu, J.-F.5
Lin, C.-W.6
Cheng, Y.-M.7
Hsu, Y.-C.8
-
29
-
-
44149124776
-
Chaperone-dependent stabilization and degradation of p53 mutants
-
Muller P., Hrstka R., Coomber D., Lane D.P., Vojtesek B. Chaperone-dependent stabilization and degradation of p53 mutants. Oncogene 2008, 27:3371-3383.
-
(2008)
Oncogene
, vol.27
, pp. 3371-3383
-
-
Muller, P.1
Hrstka, R.2
Coomber, D.3
Lane, D.P.4
Vojtesek, B.5
-
30
-
-
17844362452
-
Bid acts on the permeability transition pore complex to induce apoptosis
-
Zamzami N., Hamel C.E., Maisse C., Brenner C., Munäoz-Pinedo C., Belzacq A-S., Costantini P., Vieira H., Loeer M., Molle G., Kroemer G. Bid acts on the permeability transition pore complex to induce apoptosis. Oncogene 2000, 19:6342-6350.
-
(2000)
Oncogene
, vol.19
, pp. 6342-6350
-
-
Zamzami, N.1
Hamel, C.E.2
Maisse, C.3
Brenner, C.4
Munäoz-Pinedo, C.5
Belzacq, A.-S.6
Costantini, P.7
Vieira, H.8
Loeer, M.9
Molle, G.10
Kroemer, G.11
-
31
-
-
48249116801
-
Proapoptotic Bad and Bid protein expression predict survival in stages II and III colon cancers
-
Sinicrope F.A., Rego R.L., Foster N.R., Thibodeau S.N., Alberts S.R., Windschitl H.E., Sargent D.J. Proapoptotic Bad and Bid protein expression predict survival in stages II and III colon cancers. Clin. Cancer Res. 2008, 14:4128-4133.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4128-4133
-
-
Sinicrope, F.A.1
Rego, R.L.2
Foster, N.R.3
Thibodeau, S.N.4
Alberts, S.R.5
Windschitl, H.E.6
Sargent, D.J.7
-
32
-
-
45549088083
-
HSP27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism
-
Havasi A., Li Z., Wang Z., Martin J.L., Botla V., Ruchalski K., Schwartz J.H., Borkan S.C. HSP27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism. J. Biol. Chem. 2008, 283:12305-12313.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 12305-12313
-
-
Havasi, A.1
Li, Z.2
Wang, Z.3
Martin, J.L.4
Botla, V.5
Ruchalski, K.6
Schwartz, J.H.7
Borkan, S.C.8
-
33
-
-
72249088988
-
Heat shock protein 90 inhibitors: new mode of therapy to overcome endocrine resistance
-
Wong C., Chen S. Heat shock protein 90 inhibitors: new mode of therapy to overcome endocrine resistance. Cancer Res. 2009, 69:8670-8677.
-
(2009)
Cancer Res.
, vol.69
, pp. 8670-8677
-
-
Wong, C.1
Chen, S.2
|