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Volumn 7, Issue 5, 2012, Pages 541-554

Radioactive iodine-refractory differentiated thyroid cancer: Unmet needs and future directions

Author keywords

kinase inhibitors; MAPK ERK; PI3 Akt; RAF; RAS; RET; thyroid cancer

Indexed keywords

ANTINEOPLASTIC AGENT; AXITINIB; BEVACIZUMAB; BLEOMYCIN; CARBOPLATIN; CEDIRANIB; CISPLATIN; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; EVEROLIMUS; IODINE 131; LENALIDOMIDE; LENVATINIB; MELPHALAN; METHOTREXATE; MITOGEN ACTIVATED PROTEIN KINASE; MITOXANTRONE; PANOBINOSTAT; PASIREOTIDE; PAZOPANIB; PHOSPHATIDYLINOSITOL 3 KINASE; SORAFENIB; SUNITINIB; TEMSIROLIMUS; VALPROIC ACID; VANDETANIB; VEMURAFENIB;

EID: 84867638314     PISSN: 17446651     EISSN: 17448417     Source Type: Journal    
DOI: 10.1586/eem.12.36     Document Type: Review
Times cited : (48)

References (125)
  • 3
    • 0032535770 scopus 로고    scopus 로고
    • A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995
    • DOI 10.1002/(SICI)1097-0142(19981215)83:12<2638::AID-CNCR31>3.0. CO;2-1
    • Hundahl SA, Fleming ID, Fremgen AM, Menck HR. A National Cancer Data Base report on 53, 856 cases of thyroid carcinoma treated in the U.S., 1985-1995. Cancer 83(12), 2638-2648 (1998). (Pubitemid 29019586)
    • (1998) Cancer , vol.83 , Issue.12 , pp. 2638-2648
    • Hundahl, S.A.1    Fleming, I.D.2    Fremgen, A.M.3    Menck, H.R.4
  • 4
    • 0025327895 scopus 로고
    • Anaplastic carcinoma of the thyroid. A clinicopathologic study of 121 cases
    • DOI 10.1002/1097-0142(19900715)66:2<321::AID-CNCR2820660221>3.0. CO;2-A
    • Venkatesh YS, Ordonez NG, Schultz PN, Hickey RC, Goepfert H, Samaan NA. Anaplastic carcinoma of the thyroid. A clinicopathologic study of 121 cases. Cancer 66(2), 321-330 (1990). (Pubitemid 20205915)
    • (1990) Cancer , vol.66 , Issue.2 , pp. 321-330
    • Swamy Venkatesh, Y.S.1    Ordonez, N.G.2    Schultz, P.N.3    Hickey, R.C.4    Goepfert, H.5    Samaan, N.A.6
  • 6
    • 0018648251 scopus 로고
    • A prognostic index for thyroid carcinoma. A study of the E.O.R.T.C. thyroid cancer cooperative group
    • Byar D P, Green SB, Dor P et al. A prognostic index for thyroid carcinoma. A study of the E.O.R.T.C. Thyroid Cancer Cooperative Group. Eur. J. Cancer 15(8), 1033-1041 (1979). (Pubitemid 9254743)
    • (1979) European Journal of Cancer and Clinical Oncology , vol.15 , Issue.8 , pp. 1033-1041
    • Byar, D.P.1    Green, S.B.2    Dor, P.3
  • 7
    • 0024232116 scopus 로고
    • An expanded view of risk-group definition in differentiated thyroid carcinoma
    • Cady B, Rossi R. An expanded view of risk-group defnition in differentiated thyroid carcinoma. Surgery 104(6), 947-953 (1988). (Pubitemid 19011971)
    • (1988) Surgery , vol.104 , Issue.6 , pp. 947-953
    • Cady, B.1    Rossi, R.2    Hay, I.3    Cohn, K.H.4    Thompson, N.W.5
  • 9
    • 70449370231 scopus 로고    scopus 로고
    • American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer
    • Cooper DS, Doherty GM, Haugen BR et al American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 19(11), 1167-1214 (2009).
    • (2009) Thyroid , vol.19 , Issue.11 , pp. 1167-1214
    • Cooper, D.S.1    Doherty, G.M.2    Haugen, B.R.3
  • 10
    • 79952774799 scopus 로고    scopus 로고
    • American Joint Committee on Cancer
    • Springer, New York, NY, USA
    • Edge SB; American Joint Committee on Cancer. AJCC Cancer Staging Manual. Springer, New York, NY, USA (2010).
    • (2010) AJCC Cancer Staging Manual
    • Edge, S.B.1
  • 11
    • 0027135424 scopus 로고
    • Predicting outcome in papillary thyroid carcinoma: Development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989
    • discussion 1057
    • Hay ID, Bergstralh EJ, Goellner JR, Ebersold JR, Grant CS. Predicting outcome in papillary thyroid carcinoma: development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989. Surgery 114(6), 1050-1057; discussion 1057 (1993).
    • (1993) Surgery , vol.114 , Issue.6 , pp. 1050-11057
    • Hay, I.D.1    Bergstralh, E.J.2    Goellner, J.R.3    Ebersold, J.R.4    Grant, C.S.5
  • 13
    • 52449123946 scopus 로고    scopus 로고
    • Guidelines for radioiodine therapy of differentiated thyroid cancer
    • Luster M, Clarke SE, Dietlein M et al.; European Association of Nuclear Medicine (EANM). Guidelines for radioiodine therapy of differentiated thyroid cancer. Eur. J. Nucl. Med. Mol. Imaging 35(10), 1941-1959 (2008).
    • (2008) Eur. J. Nucl. Med. Mol. Imaging , vol.35 , Issue.10 , pp. 1941-1959
    • Luster, M.1    Clarke, S.E.2    Dietlein, M.3
  • 14
    • 70849127614 scopus 로고    scopus 로고
    • Recommendations of the Latin American Thyroid Society on diagnosis and management of differentiated thyroid cancer
    • Pitoia F, Ward L, Wohllk N et al. Recommendations of the Latin American Thyroid Society on diagnosis and management of differentiated thyroid cancer. Arq. Bras. Endocrinol. Metabol. 53(7), 884-887 (2009).
    • (2009) Arq. Bras. Endocrinol. Metabol. , vol.53 , Issue.7 , pp. 884-887
    • Pitoia, F.1    Ward, L.2    Wohllk, N.3
  • 15
    • 78651318313 scopus 로고    scopus 로고
    • Therapeutic strategy for differentiated thyroid carcinoma in Japan based on a newly established guideline managed by Japanese Society of Thyroid Surgeons and Japanese Association of Endocrine Surgeons
    • Takami H, Ito Y, Okamoto T, Yoshida A. Therapeutic strategy for differentiated thyroid carcinoma in Japan based on a newly established guideline managed by Japanese Society of Thyroid Surgeons and Japanese Association of Endocrine Surgeons. World J. Surg. 35(1), 111-121 (2011).
    • (2011) World J. Surg. , vol.35 , Issue.1 , pp. 111-121
    • Takami, H.1    Ito, Y.2    Okamoto, T.3    Yoshida, A.4
  • 17
    • 77955557317 scopus 로고    scopus 로고
    • Three distinctly different kinds of papillary thyroid microcarcinoma should be recognized: Our treatment strategies and outcomes
    • Sugitani I, Toda K, Yamada K, Yamamoto N, Ikenaga M, Fujimoto Y. Three distinctly different kinds of papillary thyroid microcarcinoma should be recognized: our treatment strategies and outcomes. World J. Surg. 34(6), 1222-1231 (2010).
    • (2010) World J. Surg. , vol.34 , Issue.6 , pp. 1222-1231
    • Sugitani, I.1    Toda, K.2    Yamada, K.3    Yamamoto, N.4    Ikenaga, M.5    Fujimoto, Y.6
  • 18
    • 0019522882 scopus 로고
    • Papillary thyroid carcinoma: A 10 year follow-up report of the impact of therapy in 576 patients
    • DOI 10.1016/0002-9343(81)90573-8
    • Mazzaferri EL, Young RL. Papillary thyroid carcinoma: a 10 year follow-up report of the impact of therapy in 576 patients. Am. J. Med. 70(3), 511-518 (1981). (Pubitemid 11153883)
    • (1981) American Journal of Medicine , vol.70 , Issue.3 , pp. 511-518
    • Mazzaferri, E.L.1    Young, R.L.2
  • 20
    • 0026768192 scopus 로고
    • The results of various modalities of treatment of well differentiated thyroid carcinomas: A retrospective review of 1599 patients
    • Samaan NA, Schultz PN, Hickey RC et al. The results of various modalities of treatment of well differentiated thyroid carcinomas: a retrospective review of 1599 patients. J. Clin. Endocrinol. Metab. 75(3), 714-720 (1992).
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , Issue.3 , pp. 714-720
    • Samaan, N.A.1    Schultz, P.N.2    Hickey, R.C.3
  • 22
    • 79955024097 scopus 로고    scopus 로고
    • Clinical presentation and clinical outcomes in Chernobyl-related paediatric thyroid cancers: What do we know now? What can we expect in the future?
    • Tuttle RM, Vaisman F, Tronko MD. Clinical presentation and clinical outcomes in Chernobyl-related paediatric thyroid cancers: what do we know now? What can we expect in the future? Clin. Oncol. (R. Coll. Radiol). 23(4), 268-275 (2011).
    • (2011) Clin. Oncol. (R. Coll. Radiol). , vol.23 , Issue.4 , pp. 268-275
    • Tuttle, R.M.1    Vaisman, F.2    Tronko, M.D.3
  • 23
    • 0030039055 scopus 로고    scopus 로고
    • Optimal surgery for papillary thyroid carcinoma
    • DOI 10.1007/s002689900016
    • Udelsman R, Lakatos E, Ladenson P. Optimal surgery for papillary thyroid carcinoma. World J. Surg. 20(1), 88-93 (1996). (Pubitemid 26006204)
    • (1996) World Journal of Surgery , vol.20 , Issue.1 , pp. 88-93
    • Udelsman, R.1    Lakatos, E.2    Ladenson, P.3
  • 26
    • 0025091281 scopus 로고
    • Ablative radioactive iodine therapy for apparently localized thyroid carcinoma. A decision analytic perspective
    • Wong JB, Kaplan MM, Meyer KB, Pauker SG. Ablative radioactive iodine therapy for apparently localized thyroid carcinoma. A decision analytic perspective. Endocrinol. Metab. Clin. North Am. 19(3), 741-760 (1990). (Pubitemid 20282665)
    • (1990) Endocrinology and Metabolism Clinics of North America , vol.19 , Issue.3 , pp. 741-760
    • Wong, J.B.1    Kaplan, M.M.2    Meyer, K.B.3    Pauker, S.G.4
  • 27
    • 4043053194 scopus 로고    scopus 로고
    • A systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer
    • DOI 10.1210/jc.2003-031167
    • Sawka AM, Thephamongkhol K, Brouwers M, Thabane L, Browman G, Gerstein HC. Clinical review 170: a systematic review and metaanalysis of the effectiveness of radioactive iodine remnant ablation for well-differentiated thyroid cancer. J. Clin. Endocrinol. Metab. 89(8), 3668-3676 (2004). (Pubitemid 39089119)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.8 , pp. 3668-3676
    • Sawka, A.M.1    Thephamongkhol, K.2    Brouwers, M.3    Thabane, L.4    Browman, G.5    Gerstein, H.C.6
  • 28
    • 77949271510 scopus 로고    scopus 로고
    • No survival difference after successful (131)I ablation between patients with initially low-risk and high-risk differentiated thyroid cancer
    • Verburg FA, Stokkel M P, Düren C et al. No survival difference after successful (131)I ablation between patients with initially low-risk and high-risk differentiated thyroid cancer. Eur. J. Nucl. Med. Mol. Imaging 37(2), 276-283 (2010).
    • (2010) Eur. J. Nucl. Med. Mol. Imaging , vol.37 , Issue.2 , pp. 276-283
    • Verburg, F.A.1    Stokkel, M.P.2    Düren, C.3
  • 29
    • 33846151068 scopus 로고    scopus 로고
    • 131I activity for remnant ablation in patients with differentiated thyroid cancer: A systematic review
    • DOI 10.1210/jc.2006-1345
    • Hackshaw A, Harmer C, Mallick U, Haq M, Franklyn JA. 131I activity for remnant ablation in patients with differentiated thyroid cancer: a systematic review. J. Clin. Endocrinol. Metab. 92(1), 28-38 (2007). (Pubitemid 46075005)
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , Issue.1 , pp. 28-38
    • Hackshaw, A.1    Harmer, C.2    Mallick, U.3    Haq, M.4    Franklyn, J.A.5
  • 31
    • 84860443135 scopus 로고    scopus 로고
    • Recombinant human thyroid stimulating hormone in thyroid remnant ablation with 1.1 GBq 131iodine in low-risk patients
    • Rosario P W, Xavier AC. Recombinant human thyroid stimulating hormone in thyroid remnant ablation with 1.1 GBq 131iodine in low-risk patients. Am. J. Clin. Oncol. 35(2), 101-104 (2012).
    • (2012) Am. J. Clin. Oncol. , vol.35 , Issue.2 , pp. 101-104
    • Rosario, P.W.1    Xavier, A.C.2
  • 32
    • 0026769603 scopus 로고
    • Radioiodine-131 therapy for well-differentiated thyroid cancer - A quantitative radiation dosimetric approach: Outcome and validation in 85 patients
    • Maxon HR 3rd, Englaro EE, Thomas SR et al. Radioiodine-131 therapy for well-differentiated thyroid cancer - a quantitative radiation dosimetric approach: outcome and validation in 85 patients. J. Nucl. Med. 33(6), 1132-1136 (1992).
    • (1992) J. Nucl. Med. , vol.33 , Issue.6 , pp. 1132-1136
    • Maxon III, H.R.1    Englaro, E.E.2    Thomas, S.R.3
  • 33
    • 0036401262 scopus 로고    scopus 로고
    • Preparation for radioactive iodine administration in differentiated thyroid cancer patients
    • DOI 10.1046/j.1365-2265.2002.01631.x
    • Liel Y. Preparation for radioactive iodine administration in differentiated thyroid cancer patients. Clin. Endocrinol. (Oxf) 57(4), 523-527 (2002). (Pubitemid 35216304)
    • (2002) Clinical Endocrinology , vol.57 , Issue.4 , pp. 523-527
    • Liel, Y.1
  • 35
    • 68349084404 scopus 로고    scopus 로고
    • Unexpected effect of furosemide on radioiodine urinary excretion in patients with differentiated thyroid carcinomas treated with iodine 131
    • Matovic MD, Jankovic SM, Jeremic M, Tasic Z, Vlajkovic M. Unexpected effect of furosemide on radioiodine urinary excretion in patients with differentiated thyroid carcinomas treated with iodine 131. Thyroid 19(8), 843-848 (2009).
    • (2009) Thyroid , vol.19 , Issue.8 , pp. 843-848
    • Matovic, M.D.1    Jankovic, S.M.2    Jeremic, M.3    Tasic, Z.4    Vlajkovic, M.5
  • 36
    • 84055184770 scopus 로고    scopus 로고
    • Approach to the patient with advanced differentiated thyroid cancer
    • Schlumberger M, Sherman SI. Approach to the patient with advanced differentiated thyroid cancer. Eur. J. Endocrinol. 166(1), 5-11 (2012).
    • (2012) Eur. J. Endocrinol. , vol.166 , pp. 15-11
    • Schlumberger, M.1    Sherman, S.I.2
  • 38
    • 50649101341 scopus 로고    scopus 로고
    • Refractory thyroid cancer: A paradigm shift in treatment is not far off
    • Pfster DG, Fagin JA. Refractory thyroid cancer: a paradigm shift in treatment is not far off. J. Clin. Oncol. 26(29), 4701-4704 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.29 , pp. 4701-4704
    • Pfster, D.G.1    Fagin, J.A.2
  • 39
    • 57849117384 scopus 로고    scopus 로고
    • New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
    • Eisenhauer EA, Therasse P, Bogaerts J et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur. J. Cancer 45(2), 228-247 (2009).
    • (2009) Eur. J. Cancer , vol.45 , Issue.2 , pp. 228-247
    • Eisenhauer, E.A.1    Therasse, P.2    Bogaerts, J.3
  • 40
    • 0028276609 scopus 로고
    • Results of external beam radiotherapy in differentiated thyroid carcinoma: A retrospective study from the Royal Marsden Hospital
    • DOI 10.1016/0959-8049(94)90284-4
    • O'Connell ME, A'Hern R P, Harmer CL. Results of external beam radiotherapy in differentiated thyroid carcinoma: a retrospective study from the Royal Marsden Hospital. Eur. J. Cancer 30A(6), 733-739 (1994). (Pubitemid 24217325)
    • (1994) European Journal of Cancer Part A: General Topics , vol.30 , Issue.6 , pp. 733-739
    • O'Connell, M.E.A.1    A'Hern, R.P.2    Harmer, C.L.3
  • 41
    • 67649556616 scopus 로고    scopus 로고
    • Postoperative external beam radiotherapy for differentiated thyroid cancer: Outcomes and morbidity with conformal treatment
    • Schwartz DL, Lobo MJ, Ang KK et al. Postoperative external beam radiotherapy for differentiated thyroid cancer: outcomes and morbidity with conformal treatment. Int. J. Radiat. Oncol. Biol. Phys. 74(4), 1083-1091 (2009).
    • (2009) Int. J. Radiat. Oncol. Biol. Phys. , vol.74 , Issue.4 , pp. 1083-1091
    • Schwartz, D.L.1    Lobo, M.J.2    Ang, K.K.3
  • 42
    • 77954762933 scopus 로고    scopus 로고
    • Cytotoxic chemotherapy for differentiated thyroid carcinoma
    • Sherman SI. Cytotoxic chemotherapy for differentiated thyroid carcinoma. Clin. Oncol. (R. Coll. Radiol). 22(6), 464-468 (2010).
    • (2010) Clin. Oncol. (R. Coll. Radiol). , vol.22 , Issue.6 , pp. 464-468
    • Sherman, S.I.1
  • 43
    • 0016131636 scopus 로고
    • New chemotherapeutic agents - Bleomycin and adriamycin. CA
    • Carter SK, Blum RH. New chemotherapeutic agents - bleomycin and adriamycin. CA. Cancer J. Clin. 24(6), 322-331 (1974).
    • (1974) Cancer J. Clin. , vol.24 , Issue.6 , pp. 322-331
    • Carter, S.K.1    Blum, R.H.2
  • 44
    • 0016401039 scopus 로고
    • Chemotherapy of thyroid cancer with adriamycin. Experience with 30 patients
    • Gottlieb JA, Hill CS Jr. Chemotherapy of thyroid cancer with adriamycin. Experience with 30 patients. N. Engl. J. Med. 290(4), 193-197 (1974).
    • (1974) N. Engl. J. Med. , vol.290 , Issue.4 , pp. 193-197
    • Gottlieb, J.A.1    Hill, Jr.C.S.2
  • 45
    • 0031723678 scopus 로고    scopus 로고
    • Management of the patient with progressive radioiodine non-responsive disease
    • Haugen BR. Management of the patient with progressive radioiodine non-responsive disease. Semin. Surg. Oncol. 16(1), 34-41 (1999).
    • (1999) Semin. Surg. Oncol. , vol.16 , Issue.1 , pp. 34-41
    • Haugen, B.R.1
  • 47
    • 0022355480 scopus 로고
    • A randomized trial of doxorubicin versus doxorubicin plus cisplatin in patients with advanced thyroid carcinoma
    • DOI 10.1002/1097-0142(19851101)56:9<2155::AID-CNCR2820560903>3.0. CO;2-E
    • Shimaoka K, Schoenfeld DA, DeWys WD, Creech RH, DeConti R. A randomized trial of doxorubicin versus doxorubicin plus cisplatin in patients with advanced thyroid carcinoma. Cancer 56(9), 2155-2160 (1985). (Pubitemid 16236586)
    • (1985) Cancer , vol.56 , Issue.9 , pp. 2155-2160
    • Shimaoka, K.1    Schoenfeld, D.A.2    DeWys, W.D.3
  • 48
    • 0029556911 scopus 로고
    • Thyroid cancer: Different outcomes to chemotherapy according to tumour histology
    • Biganzoli L, Gebbia V, Maiorino L, Caraci P, Iirillo A. Thyroid cancer: different outcomes to chemotherapy according to tumour histology. Eur. J. Cancer 31A(13-14), 2423-2424 (1995).
    • (1995) Eur. J. Cancer , vol.31 A , pp. 2423-2424
    • Biganzoli, L.1    Gebbia, V.2    Maiorino, L.3    Caraci, P.4    Iirillo, A.5
  • 49
    • 40549120349 scopus 로고    scopus 로고
    • A phase II trial of doxorubicin and interferon alpha 2b in advanced, non-medullary thyroid cancer
    • DOI 10.1007/s10637-007-9091-2
    • Argiris A, Agarwala SS, Karamouzis MV, Burmeister LA, Carty SE. A Phase II trial of doxorubicin and interferon a 2b in advanced, non-medullary thyroid cancer. Invest. New Drugs 26(2), 183-188 (2008). (Pubitemid 351357713)
    • (2008) Investigational New Drugs , vol.26 , Issue.2 , pp. 183-188
    • Argiris, A.1    Agarwala, S.S.2    Karamouzis, M.V.3    Burmeister, L.A.4    Carty, S.E.5
  • 50
    • 34447629340 scopus 로고    scopus 로고
    • Docetaxel administration for radioiodine-resistant patients with metastatic papillary thyroid carcinoma
    • Ikeda M, Tanaka K, Sonoo H et al. Docetaxel administration for radioiodine-resistant patients with metastatic papillary thyroid carcinoma. Gan To Kagaku Ryoho. 34(6), 933-936 (2007).
    • (2007) Gan to Kagaku Ryoho. , vol.34 , Issue.6 , pp. 933-936
    • Ikeda, M.1    Tanaka, K.2    Sonoo, H.3
  • 51
    • 73949123850 scopus 로고    scopus 로고
    • Chemotherapy with paclitaxel and gemcitabine in progressive medullary and thyroid carcinoma of the follicular epithelium
    • Matuszczyk A, Petersenn S, Voigt W et al. Chemotherapy with paclitaxel and gemcitabine in progressive medullary and thyroid carcinoma of the follicular epithelium. Horm. Metab. Res. 42(1), 61-64 (2010).
    • (2010) Horm. Metab. Res. , vol.42 , Issue.1 , pp. 61-64
    • Matuszczyk, A.1    Petersenn, S.2    Voigt, W.3
  • 52
    • 56649105350 scopus 로고    scopus 로고
    • Molecular pathology of thyroid cancer: Diagnostic and clinical implications
    • Fagin JA, Mitsiades N. Molecular pathology of thyroid cancer: diagnostic and clinical implications. Best Pract. Res. Clin. Endocrinol. Metab. 22(6), 955-969 (2008).
    • (2008) Best Pract. Res. Clin. Endocrinol. Metab. , vol.22 , Issue.6 , pp. 955-969
    • Fagin, J.A.1    Mitsiades, N.2
  • 53
    • 33847072340 scopus 로고    scopus 로고
    • RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis
    • Ciampi R, Nikiforov YE. RET/PTC rearrangements and BRAF mutations in thyroid tumorigenesis. Endocrinology 148(3), 936-941 (2007).
    • (2007) Endocrinology , vol.148 , Issue.3 , pp. 936-941
    • Ciampi, R.1    Nikiforov, Y.E.2
  • 54
    • 77953497704 scopus 로고    scopus 로고
    • Carcinogenesis and therapeutic strategies in thyroid cancer
    • Liu ZM, Wu TT, van Hasselt CA, Chen GG. Carcinogenesis and therapeutic strategies in thyroid cancer. Curr. Drug Targets 11(6), 716-732 (2010).
    • (2010) Curr. Drug Targets , vol.11 , Issue.6 , pp. 716-732
    • Liu, Z.M.1    Wu, T.T.2    Van Hasselt, C.A.3    Chen, G.G.4
  • 55
    • 78349300635 scopus 로고    scopus 로고
    • Genetic alterations in the phosphatidylinositol-3 kinase/Akt pathway in thyroid cancer
    • Xing M. Genetic alterations in the phosphatidylinositol-3 kinase/Akt pathway in thyroid cancer. Thyroid 20(7), 697-706 (2010).
    • (2010) Thyroid , vol.20 , Issue.7 , pp. 697-706
    • Xing, M.1
  • 56
    • 0030862873 scopus 로고    scopus 로고
    • Structure and organization of the human TRKA gene encoding a high affnity receptor for nerve growth factor
    • Indo Y, Mardy S, Tsuruta M, Karim MA, Matsuda I. Structure and organization of the human TRKA gene encoding a high affnity receptor for nerve growth factor. Jpn. J. Hum. Genet. 42(2), 343-351 (1997).
    • (1997) Jpn. J. Hum. Genet. , vol.42 , Issue.2 , pp. 343-351
    • Indo, Y.1    Mardy, S.2    Tsuruta, M.3    Karim, M.A.4    Matsuda, I.5
  • 57
    • 75349102681 scopus 로고    scopus 로고
    • The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function
    • Wang H, Hughes I, Planer W et al. The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function. J. Neurosci. 30(4), 1523-1538 (2010).
    • (2010) J. Neurosci. , vol.30 , Issue.4 , pp. 1523-1538
    • Wang, H.1    Hughes, I.2    Planer, W.3
  • 58
    • 0028810126 scopus 로고
    • Molecular defects in thyroid carcinomas: Role of the RET oncogene in thyroid neoplastic transformation
    • Santoro M, Grieco M, Melillo RM, Fusco A, Vecchio G. Molecular defects in thyroid carcinomas: role of the RET oncogene in thyroid neoplastic transformation. Eur. J. Endocrinol. 133(5), 513-522 (1995).
    • (1995) Eur. J. Endocrinol. , vol.133 , Issue.5 , pp. 513-522
    • Santoro, M.1    Grieco, M.2    Melillo, R.M.3    Fusco, A.4    Vecchio, G.5
  • 59
    • 0031931662 scopus 로고    scopus 로고
    • RET/NTRK1 rearrangements in thyroid gland tumors of the papillary carcinoma family: Correlation with clinicopathological features
    • Bongarzone I, Vigneri P, Mariani L, Collini P, Pilotti S, Pierotti MA. RET/NTRK1 rearrangements in thyroid gland tumors of the papillary carcinoma family: correlation with clinicopathological features. Clin. Cancer Res. 4(1), 223-228 (1998). (Pubitemid 28062900)
    • (1998) Clinical Cancer Research , vol.4 , Issue.1 , pp. 223-228
    • Bongarzone, I.1    Vigneri, P.2    Mariani, L.3    Collini, P.4    Pilotti, S.5    Pierotti, M.A.6
  • 60
    • 0035908493 scopus 로고    scopus 로고
    • Blocking oncogenic Ras signaling for cancer therapy
    • Adjei AA. Blocking oncogenic Ras signaling for cancer therapy. J. Natl Cancer Inst. 93(14), 1062-1074 (2001). (Pubitemid 32717538)
    • (2001) Journal of the National Cancer Institute , vol.93 , Issue.14 , pp. 1062-1074
    • Adjei, A.A.1
  • 61
    • 85047687680 scopus 로고    scopus 로고
    • Molecular profile and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma: An unusually high prevalence of ras mutations
    • DOI 10.1309/ND8D-9LAJ-TRCT-G6QD
    • Zhu Z, Gandhi M, Nikiforova MN, Fischer AH, Nikiforov YE. Molecular profle and clinical-pathologic features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations. Am. J. Clin. Pathol. 120(1), 71-77 (2003). (Pubitemid 37046372)
    • (2003) American Journal of Clinical Pathology , vol.120 , Issue.1 , pp. 71-77
    • Zhu, Z.1    Gandhi, M.2    Nikiforova, M.N.3    Fischer, A.H.4    Nikiforov, Y.E.5
  • 63
    • 53749086690 scopus 로고    scopus 로고
    • BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: A 15-year median follow-up study
    • Elisei R, Ugolini C, Viola D et al. BRAF(V600E) mutation and outcome of patients with papillary thyroid carcinoma: a 15-year median follow-up study. J. Clin. Endocrinol. Metab. 93(10), 3943-3949 (2008).
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.10 , pp. 3943-3949
    • Elisei, R.1    Ugolini, C.2    Viola, D.3
  • 64
    • 77950920870 scopus 로고    scopus 로고
    • Prognostic utility of BRAF mutation in papillary thyroid cancer
    • Xing M. Prognostic utility of BRAF mutation in papillary thyroid cancer. Mol. Cell. Endocrinol. 321(1), 86-93 (2010).
    • (2010) Mol. Cell. Endocrinol. , vol.321 , Issue.1 , pp. 86-93
    • Xing, M.1
  • 65
    • 62549101651 scopus 로고    scopus 로고
    • BRAF mutation in papillary thyroid carcinoma in a Japanese population: Its lack of correlation with high-risk clinicopathological features and disease-free survival of patients
    • Ito Y, Yoshida H, Maruo R et al. BRAF mutation in papillary thyroid carcinoma in a Japanese population: its lack of correlation with high-risk clinicopathological features and disease-free survival of patients. Endocr. J. 56(1), 89-97 (2009).
    • (2009) Endocr. J. , vol.56 , Issue.1 , pp. 89-97
    • Ito, Y.1    Yoshida, H.2    Maruo, R.3
  • 66
    • 0028825189 scopus 로고
    • RET/PTC oncogene activation is an early event in thyroid carcinogenesis
    • Viglietto G, Chiappetta G, Martinez-Tello FJ et al. RET/PTC oncogene activation is an early event in thyroid carcinogenesis. Oncogene 11(6), 1207-1210 (1995).
    • (1995) Oncogene , vol.11 , Issue.6 , pp. 1207-1210
    • Viglietto, G.1    Chiappetta, G.2    Martinez-Tello, F.J.3
  • 69
    • 59449089240 scopus 로고    scopus 로고
    • High rate of BRAF and RET/PTC dual mutations associated with recurrent papillary thyroid carcinoma
    • Henderson YC, Shellenberger TD, Williams MD et al. High rate of BRAF and RET/PTC dual mutations associated with recurrent papillary thyroid carcinoma. Clin. Cancer Res. 15(2), 485-491 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , Issue.2 , pp. 485-491
    • Henderson, Y.C.1    Shellenberger, T.D.2    Williams, M.D.3
  • 72
    • 63449092713 scopus 로고    scopus 로고
    • Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations
    • Gudmundsson J, Sulem P, Gudbjartsson DF et al. Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. Nat. Genet. 41(4), 460-464 (2009).
    • (2009) Nat. Genet. , vol.41 , Issue.4 , pp. 460-464
    • Gudmundsson, J.1    Sulem, P.2    Gudbjartsson, D.F.3
  • 73
    • 66749126620 scopus 로고    scopus 로고
    • Genomic sequence matters: A SNP in microRNA-146a can turn anti-apoptotic
    • Jazdzewski K, de la Chapelle A. Genomic sequence matters: a SNP in microRNA-146a can turn anti-apoptotic. Cell Cycle 8(11), 1642-1643 (2009).
    • (2009) Cell Cycle , vol.8 , Issue.11 , pp. 1642-1643
    • Jazdzewski, K.1    De La Chapelle, A.2
  • 77
    • 80655147234 scopus 로고    scopus 로고
    • Telomere length in neoplastic and nonneoplastic tissues of patients with familial and sporadic papillary thyroid cancer
    • Capezzone M, Cantara S, Marchisotta S et al. Telomere length in neoplastic and nonneoplastic tissues of patients with familial and sporadic papillary thyroid cancer. J. Clin. Endocrinol. Metab. 96(11), e1852-e1856 (2011).
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , Issue.11
    • Capezzone, M.1    Cantara, S.2    Marchisotta, S.3
  • 78
    • 80053103995 scopus 로고    scopus 로고
    • Identifcation of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis
    • Di Palma T, Conti A, de Cristofaro T, Scala S, Nitsch L, Zannini M. Identifcation of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysis. PLoS ONE 6(9), e25162 (2011).
    • (2011) PLoS ONE , vol.6
    • Di Palma, T.1    Conti, A.2    De Cristofaro, T.3    Scala, S.4    Nitsch, L.5    Zannini, M.6
  • 79
    • 77649211555 scopus 로고    scopus 로고
    • Detection of the PAX8-PPARγ fusion protein in thyroid tumors
    • Koenig RJ. Detection of the PAX8-PPARγ fusion protein in thyroid tumors. Clin. Chem. 56(3), 331-333 (2010).
    • (2010) Clin. Chem. , vol.56 , Issue.3 , pp. 331-333
    • Koenig, R.J.1
  • 85
    • 49249127826 scopus 로고    scopus 로고
    • Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers
    • Liu Z, Hou P, Ji M et al. Highly prevalent genetic alterations in receptor tyrosine kinases and phosphatidylinositol 3-kinase/akt and mitogen-activated protein kinase pathways in anaplastic and follicular thyroid cancers. J. Clin. Endocrinol. Metab. 93(8), 3106-3116 (2008).
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.8 , pp. 3106-3116
    • Liu, Z.1    Hou, P.2    Ji, M.3
  • 86
    • 1642272931 scopus 로고    scopus 로고
    • Early Occurrence of RASSF1A Hypermethylation and Its Mutual Exclusion with BRAF Mutation in Thyroid Tumorigenesis
    • DOI 10.1158/0008-5472.CAN-03-3242
    • Xing M, Cohen Y, Mambo E et al. Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis. Cancer Res. 64(5), 1664-1668 (2004). (Pubitemid 38428687)
    • (2004) Cancer Research , vol.64 , Issue.5 , pp. 1664-1668
    • Xing, M.1    Cohen, Y.2    Mambo, E.3    Tallini, G.4    Udelsman, R.5    Ladenson, P.W.6    Sidransky, D.7
  • 87
    • 80053136401 scopus 로고    scopus 로고
    • Multikinase inhibitors: A new option for the treatment of thyroid cancer
    • Gild ML, Bullock M, Robinson BG, Clifton-Bligh R. Multikinase inhibitors: a new option for the treatment of thyroid cancer. Nat. Rev. Endocrinol. 7(10), 617-624 (2011).
    • (2011) Nat. Rev. Endocrinol. , vol.7 , Issue.10 , pp. 617-624
    • Gild, M.L.1    Bullock, M.2    Robinson, B.G.3    Clifton-Bligh, R.4
  • 89
    • 77955393886 scopus 로고    scopus 로고
    • The evolving feld of tyrosine kinase inhibitors in the treatment of endocrine tumors
    • Ye L, Santarpia L, Gagel R F. The evolving feld of tyrosine kinase inhibitors in the treatment of endocrine tumors. Endocr. Rev. 31(4), 578-599 (2010).
    • (2010) Endocr. Rev. , vol.31 , Issue.4 , pp. 578-599
    • Ye, L.1    Santarpia, L.2    Gagel, R.F.3
  • 91
    • 0036277892 scopus 로고    scopus 로고
    • Serum vascular endothelial growth factor levels are elevated in metastatic differentiated thyroid cancer but not increased by short-term TSH stimulation
    • DOI 10.1210/jc.87.4.1737
    • Tuttle RM, Fleisher M, Francis GL, Robbins RJ. Serum vascular endothelial growth factor levels are elevated in metastatic differentiated thyroid cancer but not increased by short-term TSH stimulation. J. Clin. Endocrinol. Metab. 87(4), 1737-1742 (2002). (Pubitemid 34615263)
    • (2002) Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.4 , pp. 1737-1742
    • Tuttle, R.M.1    Fleisher, M.2    Francis, G.L.3    Robbins, R.J.4
  • 92
    • 77649155708 scopus 로고    scopus 로고
    • Standard and emerging therapies for metastatic differentiated thyroid cancer
    • O'Neill CJ, Oucharek J, Learoyd D, Sidhu SB. Standard and emerging therapies for metastatic differentiated thyroid cancer. Oncologist 15(2), 146-156 (2010).
    • (2010) Oncologist , vol.15 , Issue.2 , pp. 146-156
    • O'Neill, C.J.1    Oucharek, J.2    Learoyd, D.3    Sidhu, S.B.4
  • 93
    • 58749084711 scopus 로고    scopus 로고
    • The molecular basis of cancer and the development of targeted therapy
    • vii
    • Riley LB, Desai DC. The molecular basis of cancer and the development of targeted therapy. Surg. Clin. North Am. 89(1), 1-15, vii (2009).
    • (2009) Surg. Clin. North Am. , vol.89 , Issue.1 , pp. 1-15
    • Riley, L.B.1    Desai, D.C.2
  • 94
    • 79953329570 scopus 로고    scopus 로고
    • Targeted therapies for thyroid tumors
    • Sherman SI. Targeted therapies for thyroid tumors. Mod. Pathol. 24 (Suppl. 2), S44-S52 (2011).
    • (2011) Mod. Pathol. , vol.24 , Issue.SUPPL. 2
    • Sherman, S.I.1
  • 95
    • 77952896418 scopus 로고    scopus 로고
    • Targeted therapy for thyroid cancer: An updated review of investigational agents
    • Deshpande HA, Gettinger SN, Sosa JA. Targeted therapy for thyroid cancer: an updated review of investigational agents. Curr. Opin. Investig. Drugs 11(6), 661-668 (2010).
    • (2010) Curr. Opin. Investig. Drugs , vol.11 , Issue.6 , pp. 661-668
    • Deshpande, H.A.1    Gettinger, S.N.2    Sosa, J.A.3
  • 96
    • 77954476036 scopus 로고    scopus 로고
    • Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: The M. D. Anderson experience
    • Cabanillas ME, Waguespack SG, Bronstein Y et al. Treatment with tyrosine kinase inhibitors for patients with differentiated thyroid cancer: the M. D. Anderson experience. J. Clin. Endocrinol. Metab. 95(6), 2588-2595 (2010).
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , Issue.6 , pp. 2588-2595
    • Cabanillas, M.E.1    Waguespack, S.G.2    Bronstein, Y.3
  • 98
    • 84655175698 scopus 로고    scopus 로고
    • Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: A randomized, double-blind Phase III trial
    • Wells SA Jr, Robinson BG, Gagel RF et al. Vandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind Phase III trial. J. Clin. Oncol. 30(2), 134-141 (2012).
    • (2012) J. Clin. Oncol. , vol.30 , Issue.2 , pp. 134-141
    • Wells, Jr.S.A.1    Robinson, B.G.2    Gagel, R.F.3
  • 100
    • 50649095250 scopus 로고    scopus 로고
    • Phase II trial of sorafenib in advanced thyroid cancer
    • Gupta-Abramson V, Troxel AB, Nellore A et al. Phase II trial of sorafenib in advanced thyroid cancer. J. Clin. Oncol. 26(29), 4714-4719 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.29 , pp. 4714-4719
    • Gupta-Abramson, V.1    Troxel, A.B.2    Nellore, A.3
  • 101
    • 80053612152 scopus 로고    scopus 로고
    • Phase II trial of sorafenib in patients with advanced thyroid cancer
    • abstract 5562
    • Keefe SM, Troxel AB, Rhee S et al. Phase II trial of sorafenib in patients with advanced thyroid cancer. J. Clin. Oncol. 29(Suppl. 15), abstract 5562 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.SUPPL. 15
    • Keefe, S.M.1    Troxel, A.B.2    Rhee, S.3
  • 102
    • 63849265332 scopus 로고    scopus 로고
    • Phase II trial of sorafenib in metastatic thyroid cancer
    • Kloos RT, Ringel MD, Knopp MV et al. Phase II trial of sorafenib in metastatic thyroid cancer. J. Clin. Oncol. 27(10), 1675-1684 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.10 , pp. 1675-1684
    • Kloos, R.T.1    Ringel, M.D.2    Knopp, M.V.3
  • 103
    • 79960179069 scopus 로고    scopus 로고
    • Analysis of the effcacy and toxicity of sorafenib in thyroid cancer: A Phase II study in a UK based population
    • Ahmed M, Barbachano Y, Riddell A et al. Analysis of the effcacy and toxicity of sorafenib in thyroid cancer: a Phase II study in a UK based population. Eur. J. Endocrinol. 165(2), 315-322 (2011).
    • (2011) Eur. J. Endocrinol. , vol.165 , Issue.2 , pp. 315-322
    • Ahmed, M.1    Barbachano, Y.2    Riddell, A.3
  • 104
    • 72949106263 scopus 로고    scopus 로고
    • Benefcial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma
    • Hoftijzer H, Heemstra KA, Morreau H et al. Benefcial effects of sorafenib on tumor progression, but not on radioiodine uptake, in patients with differentiated thyroid carcinoma. Eur. J. Endocrinol. 161(6), 923-931 (2009).
    • (2009) Eur. J. Endocrinol. , vol.161 , Issue.6 , pp. 923-931
    • Hoftijzer, H.1    Heemstra, K.A.2    Morreau, H.3
  • 106
    • 80051479922 scopus 로고    scopus 로고
    • Rationale and design of decision: A double-blind, randomized, placebo-controlled Phase III trial evaluating the effcacy and safety of sorafenib in patients with locally advanced or metastatic radioactive iodine (RAI)-refractory, differentiated thyroid cancer
    • Brose MS, Nutting CM, Sherman SI et al. Rationale and design of decision: a double-blind, randomized, placebo-controlled Phase III trial evaluating the effcacy and safety of sorafenib in patients with locally advanced or metastatic radioactive iodine (RAI)-refractory, differentiated thyroid cancer. BMC Cancer 11, 349 (2011).
    • (2011) BMC Cancer , vol.11 , Issue.349
    • Brose, M.S.1    Nutting, C.M.2    Sherman, S.I.3
  • 107
    • 79960554999 scopus 로고    scopus 로고
    • E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion
    • Glen H, Mason S, Patel H, Macleod K, Brunton VG. E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion. BMC Cancer 11, 309 (2011).
    • (2011) BMC Cancer , vol.11 , Issue.309
    • Glen, H.1    Mason, S.2    Patel, H.3    MacLeod, K.4    Brunton, V.G.5
  • 108
    • 80053160399 scopus 로고    scopus 로고
    • A Phase II trial of the multitargeted kinase inhibitor E7080 in advanced radioiodine (RAI)-refractory differentiated thyroid cancer (DTC)
    • abstract 5503
    • Sherman SI, Jarzab B, Cabanillas ME et al. A Phase II trial of the multitargeted kinase inhibitor E7080 in advanced radioiodine (RAI)-refractory differentiated thyroid cancer (DTC). J. Clin. Oncol. 29(Suppl. 15), abstract 5503 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.SUPPL. 15
    • Sherman, S.I.1    Jarzab, B.2    Cabanillas, M.E.3
  • 110
    • 42349094498 scopus 로고    scopus 로고
    • Sustained clinical responses to tyrosine kinase inhibitor sunitinib in thyroid carcinoma
    • DOI 10.1097/CAD.0b013e3282fc6cf7, PII 0000181320080600000012
    • Dawson SJ, Conus NM, Toner GC et al. Sustained clinical responses to tyrosine kinase inhibitor sunitinib in thyroid carcinoma. Anticancer Drugs 19(5), 547-552 (2008). (Pubitemid 351556406)
    • (2008) Anti-Cancer Drugs , vol.19 , Issue.5 , pp. 547-552
    • Dawson, S.-J.1    Conus, N.M.2    Toner, G.C.3    Raleigh, J.M.4    Hicks, R.J.5    McArthur, G.6    Rischin, D.7
  • 111
    • 65749087602 scopus 로고    scopus 로고
    • Phase 2 study of sunitinib in refractory thyroid cancer
    • abstract 6025
    • Cohen EE, Needles BM, Cullen KJ, et al. Phase 2 study of sunitinib in refractory thyroid cancer. J. Clin. Oncol. 26(Suppl. 15), abstract 6025 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.SUPPL. 15
    • Cohen, E.E.1    Needles, B.M.2    Cullen, K.J.3
  • 112
    • 77649112149 scopus 로고    scopus 로고
    • Effcacy of sunitinib in advanced medullary thyroid carcinoma: Intermediate results of Phase II THYSU
    • author reply 214
    • Ravaud A, de la Fouchardière C, Asselineau J et al. Effcacy of sunitinib in advanced medullary thyroid carcinoma: intermediate results of Phase II THYSU. Oncologist 15(2), 212-213; author reply 214 (2010).
    • (2010) Oncologist , vol.15 , Issue.2 , pp. 212-213
    • Ravaud, A.1    De La Fouchardière, C.2    Asselineau, J.3
  • 113
    • 78049462514 scopus 로고    scopus 로고
    • Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation
    • Carr LL, Mankoff DA, Goulart BH et al. Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. Clin. Cancer Res. 16(21), 5260-5268 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , Issue.21 , pp. 5260-5268
    • Carr, L.L.1    Mankoff, D.A.2    Goulart, B.H.3
  • 115
    • 77957359933 scopus 로고    scopus 로고
    • Effcacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: Results of a Phase 2 consortium study
    • Bible KC, Suman VJ, Molina JR et al.; Endocrine Malignancies Disease Oriented Group; Mayo Clinic Cancer Center; Mayo Phase 2 Consortium. Effcacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a Phase 2 consortium study. Lancet Oncol. 11(10), 962-972 (2010).
    • (2010) Lancet Oncol. , vol.11 , Issue.10 , pp. 962-972
    • Bible, K.C.1    Suman, V.J.2    Molina, J.R.3
  • 116
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melamona with BRAF V600E mutation
    • Chapman PB, Hauschild A, Robert C et al; BRIM-3 Study Group. Improved survival with vemurafenib in melamona with BRAF V600E mutation. N. Engl. J. Med. 364(26), 2507-2616 (2011).
    • (2011) N. Engl. J. Med. , vol.364 , Issue.26 , pp. 2507-2616
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 117
    • 75149188152 scopus 로고    scopus 로고
    • Cytostatic activity of adenosine triphosphate-completitive kinase inhibitors in BRAF mutant thyroid carcinoma cells
    • Salerno P, De Falco V, Tamburrino A et al. Cytostatic activity of adenosine triphosphate-completitive kinase inhibitors in BRAF mutant thyroid carcinoma cells. J. Clin. Endocrinol. Metab. 95(1), 450-455 (2010).
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , Issue.1 , pp. 450-455
    • Salerno, P.1    De Falco, V.2    Tamburrino, A.3
  • 118
  • 120
    • 50649095801 scopus 로고    scopus 로고
    • Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: Results from a Phase II study
    • Cohen EE, Rosen LS, Vokes EE et al. Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: results from a Phase II study. J. Clin. Oncol. 26(29), 4708-4713 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.29 , pp. 4708-4713
    • Cohen, E.E.1    Rosen, L.S.2    Vokes, E.E.3
  • 122
    • 68949106943 scopus 로고    scopus 로고
    • A Phase i study of XL281, a selective oral RAF kinase inhibitor, in patients (Pts) with advanced solid tumors
    • abstract 3513
    • Schwartz GK, Robertson S, Shen A et al. A Phase I study of XL281, a selective oral RAF kinase inhibitor, in patients (Pts) with advanced solid tumors. J. Clin. Oncol. 27(Suppl. 15), abstract 3513 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , Issue.SUPPL. 15
    • Schwartz, G.K.1    Robertson, S.2    Shen, A.3
  • 123
    • 82255186485 scopus 로고    scopus 로고
    • Cytotoxic activity of the histone deacetylase inhibitor panobinostat (LBH589) in anaplastic thyroid cancer in vitro and in vivo
    • Catalano MG, Pugliese M, Gargantini E et al. Cytotoxic activity of the histone deacetylase inhibitor panobinostat (LBH589) in anaplastic thyroid cancer in vitro and in vivo. Int. J. Cancer 130(3), 694-704 (2012).
    • (2012) Int. J. Cancer , vol.130 , Issue.3 , pp. 694-704
    • Catalano, M.G.1    Pugliese, M.2    Gargantini, E.3
  • 124
    • 79959936054 scopus 로고    scopus 로고
    • Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer
    • Kurzrock R, Sherman SI, Ball DW et al. Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer. J. Clin. Oncol. 29(19), 2660-2666 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.19 , pp. 2660-2666
    • Kurzrock, R.1    Sherman, S.I.2    Ball, D.W.3
  • 125
    • 79960127292 scopus 로고    scopus 로고
    • Cabozantinib in medullary thyroid carcinoma: Time to focus the spotlight on this rare disease
    • Houvras Y, Wirth LJ. Cabozantinib in medullary thyroid carcinoma: time to focus the spotlight on this rare disease. J. Clin. Oncol. 29(19), 2616-2618 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.19 , pp. 2616-2618
    • Houvras, Y.1    Wirth, L.J.2


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