E2F6 Associates with BRG1 in Transcriptional Regulation

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Leung, Janet Y ^a   Nevins, Joseph R ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRG1 PROTEIN; TRANSCRIPTION FACTOR E2F4; TRANSCRIPTION FACTOR E2F6;

ARTICLE; CELL CYCLE S PHASE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME SPECIFICITY; G1 PHASE CELL CYCLE CHECKPOINT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

CHROMATIN IMMUNOPRECIPITATION; DNA HELICASES; E2F1 TRANSCRIPTION FACTOR; E2F4 TRANSCRIPTION FACTOR; E2F6 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; GENES, DOMINANT; HUMANS; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 84867627407     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047967     Document Type: Article

References (45)

1. Attwooll C, Lazzerini Denchi E, Helin K, (2004) The E2F family: specific functions and overlapping interests. EMBO J 23: 4709-4716.
2. Harbour JW, Dean DC, (2000) The Rb/E2F pathway: expanding roles and emerging paradigms. Genes Dev 14: 2393-2409.
3. Nevins JR, (1998) Toward an understanding of the functional complexity of the E2F and retinoblastoma families. Cell Growth Differ 9: 585-593.
4. Trimarchi JM, Lees JA, (2002) Sibling rivalry in the E2F family. Nat Rev Mol Cell Biol 3: 11-20.
5. Giangrande PH, Zhu W, Schlisio S, Sun X, Mori S, et al. (2004) A role for E2F6 in distinguishing G1/S- and G2/M-specific transcription. Genes Dev 18: 2941-2951.
6. Takahashi Y, Rayman JB, Dynlacht BD, (2000) Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression. Genes Dev 14: 804-816.
7. Zhu W, Giangrande PH, Nevins JR, (2004) E2Fs link the control of G1/S and G2/M transcription. EMBO J 23: 4615-4626.
8. DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR, (1997) Distinct roles for E2F proteins in cell growth control and apoptosis. Proc Natl Acad Sci U S A 94: 7245-7250.
9. Lukas J, Petersen BO, Holm K, Bartek J, Helin K, (1996) Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression. Mol Cell Biol 16: 1047-1057.
10. Verona R, Moberg K, Estes S, Starz M, Vernon JP, et al. (1997) E2F activity is regulated by cell cycle-dependent changes in subcellular localization. Mol Cell Biol 17: 7268-7282.
11. Giangrande PH, Hallstrom TC, Tunyaplin C, Calame K, Nevins JR, (2003) Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor. Mol Cell Biol 23: 3707-3720.
12. Beijersbergen RL, Kerkhoven RM, Zhu L, Carlee L, Voorhoeve PM, et al. (1994) E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo. Genes Dev 8: 2680-2690.
13. Ginsberg D, Vairo G, Chittenden T, Xiao ZX, Xu G, et al. (1994) E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes Dev 8: 2665-2679.
14. Sardet C, Vidal M, Cobrinik D, Geng Y, Onufryk C, et al. (1995) E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle. Proc Natl Acad Sci U S A 92: 2403-2407.
15. Ikeda MA, Jakoi L, Nevins JR, (1996) A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation. Proc Natl Acad Sci U S A 93: 3215-3220.
16. van Oevelen C, Wang J, Asp P, Yan Q, Kaelin WG Jr, et al. (2008) A role for mammalian Sin3 in permanent gene silencing. Mol Cell 32: 359-370.
17. Rayman JB, Takahashi Y, Indjeian VB, Dannenberg JH, Catchpole S, et al. (2002) E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex. Genes Dev 16: 933-947.
18. Cartwright P, Muller H, Wagener C, Holm K, Helin K, (1998) E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription. Oncogene 17: 611-623.
19. Gaubatz S, Wood JG, Livingston DM, (1998) Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. Proc Natl Acad Sci U S A 95: 9190-9195.
20. Li J, Ran C, Li E, Gordon F, Comstock G, et al. (2008) Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell 14: 62-75.
21. Logan N, Graham A, Zhao X, Fisher R, Maiti B, et al. (2005) E2F-8: an E2F family member with a similar organization of DNA-binding domains to E2F-7. Oncogene 24: 5000-5004.
22. Maiti B, Li J, de Bruin A, Gordon F, Timmers C, et al. (2005) Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem 280: 18211-18220.
23. Moon NS, Frolov MV, Kwon EJ, Di Stefano L, Dimova DK, et al. (2005) Drosophila E2F1 has context-specific pro- and antiapoptotic properties during development. Dev Cell 9: 463-475.
24. Trimarchi JM, Fairchild B, Verona R, Moberg K, Andon N, et al. (1998) E2F-6, a member of the E2F family that can behave as a transcriptional repressor. Proc Natl Acad Sci U S A 95: 2850-2855.
25. Storre J, Elsasser HP, Fuchs M, Ullmann D, Livingston DM, et al. (2002) Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6. EMBO Rep 3: 695-700.
26. Carlson M, Osmond BC, Botstein D, (1981) Genetic evidence for a silent SUC gene in yeast. Genetics 98: 41-54.
27. Carlson M, Osmond BC, Botstein D, (1981) Mutants of yeast defective in sucrose utilization. Genetics 98: 25-40.
28. Neigeborn L, Carlson M, (1984) Genes affecting the regulation of SUC2 gene expression by glucose repression in Saccharomyces cerevisiae. Genetics 108: 845-858.
29. Khavari PA, Peterson CL, Tamkun JW, Mendel DB, Crabtree GR, (1993) BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature 366: 170-174.
30. Randazzo FM, Khavari P, Crabtree G, Tamkun J, Rossant J, (1994) brg1: a putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator. Dev Biol 161: 229-242.
31. Leung JY, Ehmann GL, Giangrande PH, Nevins JR, (2008) A role for Myc in facilitating transcription activation by E2F1. Oncogene 27: 4172-4179.
32. Morkel M, Wenkel J, Bannister AJ, Kouzarides T, Hagemeier C, (1997) An E2F-like repressor of transcription. Nature 390: 567-568.
33. Hallstrom TC, Nevins JR, (2003) Specificity in the activation and control of transcription factor E2F-dependent apoptosis. Proc Natl Acad Sci U S A 100: 10848-10853.
34. Wang W, Cote J, Xue Y, Zhou S, Khavari PA, et al. (1996) Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. EMBO J 15: 5370-5382.
35. Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, et al. (1996) Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev 10: 2117-2130.
36. Reisman D, Glaros S, Thompson EA, (2009) The SWI/SNF complex and cancer. Oncogene 28: 1653-1668.
37. Johnson DG, Ohtani K, Nevins JR, (1994) Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. Genes Dev 8: 1514-1525.
38. Trimarchi JM, Fairchild B, Wen J, Lees JA, (2001) The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc Natl Acad Sci U S A 98: 1519-1524.
39. Ogawa H, Ishiguro K, Gaubatz S, Livingston DM, Nakatani Y, (2002) A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. Science 296: 1132-1136.
40. Nagl NG Jr, Wang X, Patsialou A, Van Scoy M, Moran E, (2007) Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control. EMBO J 26: 752-763.
41. Chi Y, Senyuk V, Chakraborty S, Nucifora G, (2003) EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activity. J Biol Chem 278: 49806-49811.
42. Wang S, Zhang B, Faller DV, (2002) Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth. EMBO J 21: 3019-3028.
43. Wang S, Zhang B, Faller DV, (2004) BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists. EMBO J 23: 2293-2303.
44. Varela I, Tarpey P, Raine K, Huang D, Ong CK, et al. (2011) Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. Nature 469: 539-542.
45. Xia W, Nagase S, Montia AG, Kalachikov SM, Keniry M, et al. (2008) BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer. Cancer Res 68: 1667-1674.