Early sedation of mechanically ventilated, critically ill patients: Another wake-up call!

American Journal of Respiratory and Critical Care Medicine

Volumn 186, Issue 8, 2012, Pages 699-

  Mehta, Sangeeta ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

SEDATIVE AGENT;

ANESTHESIA INDUCTION; ARTIFICIAL VENTILATION; AUSTRALIA; CLINICAL PROTOCOL; CRITICALLY ILL PATIENT; DEEP SEDATION; DELIRIUM; EARLY SEDATION; EDITORIAL; EXTUBATION; HUMAN; INTENSIVE CARE UNIT; MORTALITY; NEW ZEALAND; OVERSEDATION; PRIORITY JOURNAL; RISK FACTOR; SCORING SYSTEM; TREATMENT OUTCOME;

CRITICAL ILLNESS; DELIRIUM; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; RESPIRATION, ARTIFICIAL;

EID: 84867600347     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201208-1387ED     Document Type: Editorial

References (5)

1. Brook AD, Ahrens TS, Schaiff R, Prentice D, Sherman G, Shannon W, Kollef MH. Effect of a nursing-implemented sedation protocol on the duration of mechanical ventilation. Crit Care Med 1999;27:2609-2615. (Pubitemid 30027169)
2. Mehta S, Burry L, Cook D, Steinberg M, Fergusson D, Hebert P, Herridge M, Granton J, Ferguson N, Devlin J, et al.; SLEAP Investigators and Canadian Critical Care Trials Group. SLEAP: a multicenter randomized trial of daily awakening in critically ill patients being managed with a sedation protocol [abstract]. Am J Respir Crit Care Med 2012;185:A3882.
3. Kress JP, Pohlman AS, O'Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. N Engl J Med 2000;342:1471-1477. (Pubitemid 30318270)
4. Strøm T, Martinussen T, Toft P. A protocol of no sedation for critically ill patients receiving mechanical ventilation: a randomised trial. Lancet 2010;375:475-480.
5. Shehabi Y, Bellomo R, Reade MC, Bailey M, Bass F, Howe B, McArthur C, Seppelt IM, Webb S, Weisbrodt L; Sedation Practice in Intensive Care Evaluation (SPICE) Study Investigators and the ANZICS Clinical Trials Group. Early intensive care sedation predicts long-term mortality in ventilated critically ill patients. Am J Respir Crit Care Med 2012;186:724-731.