Effect of therapeutic doses of acetaminophen (up to 4 g/day) on Serum Alanine Aminotransferase Levels in subjects consuming ethanol: Systematic review and meta-analysis of randomized controlled trials

Pharmacotherapy

Volumn 32, Issue 9, 2012, Pages 784-791

  Rumack, Barry ^a,b   Heard, Kennon ^a,b   Green, Jody ^a,c   Albert, Donald ^a   Bucher Bartelson, Becki ^a,d   Bodmer, Michael ^a,e   Sivilotti, Marco L A ^f   Dart, Richard C ^a,b  

^a ROCKY MOUNTAIN POISON AND DRUG CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF NURSING   (United States)

^d Global Health and Health Disparities   (United States)

^e UNIVERSITY HOSPITAL BASEL   (Switzerland)

^f QUEEN S UNIVERSITY   (Canada)

Author keywords

Acetaminophen; Adverse drug reactions; Alanine aminotransferase; ALT; Analgesia; Ethanol; Liver

Indexed keywords

ALANINE AMINOTRANSFERASE; BILIRUBIN; GLUTATHIONE TRANSFERASE; PARACETAMOL; PLACEBO;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; BILIRUBIN BLOOD LEVEL; DRUG ALCOHOL INTERACTION; DRUG EFFECT; DRUG FATALITY; DRUG SAFETY; ENZYME ACTIVITY; HUMAN; INTERNATIONAL NORMALIZED RATIO; LIVER DYSFUNCTION; LIVER FAILURE; META ANALYSIS; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW; TREATMENT DURATION;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ALCOHOL DRINKING; ANALGESICS, NON-NARCOTIC; ETHANOL; HUMANS; LIVER FUNCTION TESTS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 84867592916     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1875-9114.2012.01122.x     Document Type: Review

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