A ferritin mutant of Mycobacterium tuberculosis is highly susceptible to killing by antibiotics and is unable to establish a chronic infection in mice

Infection and Immunity

Volumn 80, Issue 10, 2012, Pages 3650-3659

  Pandey, Ruchi ^a   Rodriguez, G Marcela ^a  

^a PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERIOFERRITIN; CIPROFLOXACIN; FERRIC ION; FERRITIN; GENTAMICIN; ISONIAZID; KANAMYCIN; MOXIFLOXACIN; RIFAMPICIN; SPECTINOMYCIN;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; IRON METABOLISM; IRON OVERLOAD; IRON STORAGE; IRON TRANSPORT; KNOCKOUT GENE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TUBERCULOSIS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; ANTITUBERCULAR AGENTS; CHRONIC DISEASE; FEMALE; FERRITINS; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; HOMEOSTASIS; IRON; LUNG; MICE; MICE, INBRED C57BL; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; OXIDATIVE STRESS; TUBERCULOSIS, PULMONARY;

EID: 84867584201     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00229-12     Document Type: Article

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