The structure of human GALNS reveals the molecular basis for mucopolysaccharidosis IV A

Journal of Molecular Biology

Volumn 423, Issue 5, 2012, Pages 736-751

  Rivera Colón, Yadilette ^a   Schutsky, Emily K ^a   Kita, Adriana Z ^a   Garman, Scott C ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

cysteine modification; enzyme replacement therapy; lysosomal storage disease; sulfatase structure; X ray crystallography

Indexed keywords

CHONDROITIN 6 SULFATE; CYSTEINE; EFEPRISTIN; KERATAN SULFATE; N ACETYLGALACTOSAMINE 6 SULFATASE; NUCLEOPHILE;

ANIMAL CELL; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; GEOMETRY; HYDROPHOBICITY; INSECT CELL; LIGAND BINDING; LYSOSOME; MASS SPECTROMETRY; MISSENSE MUTATION; MUCOPOLYSACCHARIDOSIS; MUCOPOLYSACCHARIDOSIS IV A; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; X RAY CRYSTALLOGRAPHY;

HEXAPODA;

EID: 84867583031     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.08.020     Document Type: Article

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