메뉴 건너뛰기




Volumn 18, Issue 11, 2012, Pages 2072-2078

Clinical predictors at diagnosis of disabling pediatric Crohn's disease

Author keywords

Crohn's disease; Montreal classification; pediatric

Indexed keywords

AZATHIOPRINE; BIOLOGICAL MARKER; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; MERCAPTOPURINE; METHOTREXATE;

EID: 84867573864     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.22898     Document Type: Article
Times cited : (34)

References (59)
  • 1
    • 0035188740 scopus 로고    scopus 로고
    • Behaviour of Crohn's disease according to the Vienna classification: Changing pattern over the course of the disease
    • Louis E, Collard A, Oger AF, et al. Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease. Gut. 2001; 49: 777-782.
    • (2001) Gut , vol.49 , pp. 777-782
    • Louis, E.1    Collard, A.2    Oger, A.F.3
  • 2
    • 0036061640 scopus 로고    scopus 로고
    • Long-term evolution of disease behaviour of Crohn's disease
    • Cosnes J, Cattan S, Blain A, et al. Long-term evolution of disease behaviour of Crohn's disease. Inflamm Bowel Dis. 2002; 8: 244-250.
    • (2002) Inflamm Bowel Dis , vol.8 , pp. 244-250
    • Cosnes, J.1    Cattan, S.2    Blain, A.3
  • 3
    • 36549071038 scopus 로고    scopus 로고
    • Clinical course of Crohn's disease: Results of a Norwegian population-based ten-year follow-up study
    • Solberg IC, Vatn MH, Hoie O, et al. Clinical course of Crohn's disease: results of a Norwegian population-based ten-year follow-up study. Clin Gastroenterol Hepatol. 2007; 5: 1430-1438.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 1430-1438
    • Solberg, I.C.1    Vatn, M.H.2    Hoie, O.3
  • 4
    • 76349114941 scopus 로고    scopus 로고
    • The natural history of adult Crohn's disease in population-based cohorts
    • Peyrin-Biroulet L, Loftus EV Jr, Colombel JF, et al. The natural history of adult Crohn's disease in population-based cohorts. Am J Gastroenterol. 2010; 105: 289-297.
    • (2010) Am J Gastroenterol , vol.105 , pp. 289-297
    • Peyrin-Biroulet, L.1    Loftus, Jr.E.V.2    Colombel, J.F.3
  • 5
    • 79955844087 scopus 로고    scopus 로고
    • Development of the Crohn's disease digestive damage score, the Lémann score
    • Pariente B, Cosnes J, Danese S, et al. Development of the Crohn's disease digestive damage score, the Lémann score. Inflamm Bowel Dis. 2011; 17: 1415-1422.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1415-1422
    • Pariente, B.1    Cosnes, J.2    Danese, S.3
  • 6
    • 53049110159 scopus 로고    scopus 로고
    • Natural history of pediatric Crohn's disease: A population-based cohort study
    • Vernier-Massouille G, Balde M, Salleron J, et al. Natural history of pediatric Crohn's disease: a population-based cohort study. Gastroenterology. 2008; 135: 1106-1113.
    • (2008) Gastroenterology , vol.135 , pp. 1106-1113
    • Vernier-Massouille, G.1    Balde, M.2    Salleron, J.3
  • 7
    • 33947397636 scopus 로고    scopus 로고
    • Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children
    • Hyams J, Crandall W, Kugathasan S, et al. Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children. Gastroenterology. 2007; 132: 863-873.
    • (2007) Gastroenterology , vol.132 , pp. 863-873
    • Hyams, J.1    Crandall, W.2    Kugathasan, S.3
  • 8
    • 80052775138 scopus 로고    scopus 로고
    • Long-term outcome of treatment with infliximab in pediatric-onset Crohn's disease: A population-based study
    • Crombé V, Salleron J, Savoye G, et al. Long-term outcome of treatment with infliximab in pediatric-onset Crohn's disease: a population-based study. Inflamm Bowel Dis. 2011; 17: 2144-2152.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 2144-2152
    • Crombé, V.1    Salleron, J.2    Savoye, G.3
  • 9
    • 77950988234 scopus 로고    scopus 로고
    • Infliximab, azathioprine, or combination therapy for Crohn's disease
    • Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn's disease. N Engl J Med. 2010; 362: 1383-1395.
    • (2010) N Engl J Med , vol.362 , pp. 1383-1395
    • Colombel, J.F.1    Sandborn, W.J.2    Reinisch, W.3
  • 10
    • 63849101007 scopus 로고    scopus 로고
    • Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: Results from a single-centre cohort
    • Schnitzler F, Fidder H, Ferrante M, et al. Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: results from a single-centre cohort. Gut. 2009; 58: 492-500.
    • (2009) Gut , vol.58 , pp. 492-500
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 11
    • 33846242958 scopus 로고    scopus 로고
    • Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
    • Colombel JF, Sandborn WJ, Rutgeerts P, et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology. 2007; 132: 52-65.
    • (2007) Gastroenterology , vol.132 , pp. 52-65
    • Colombel, J.F.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 12
    • 0037018761 scopus 로고    scopus 로고
    • Maintenance infliximab for Crohn's disease: The ACCENT i randomised trial
    • Hanauer SB, Feagan BG, Lichtenstein GR, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet. 2002; 359: 1541-1549.
    • (2002) Lancet , vol.359 , pp. 1541-1549
    • Hanauer, S.B.1    Feagan, B.G.2    Lichtenstein, G.R.3
  • 13
    • 10744221312 scopus 로고    scopus 로고
    • Infliximab maintenance therapy for fistulizing Crohn's disease
    • Sands BE, Anderson FH, Bernstein CN, et al. Infliximab maintenance therapy for fistulizing Crohn's disease. N Engl J Med. 2004; 350: 876-885.
    • (2004) N Engl J Med , vol.350 , pp. 876-885
    • Sands, B.E.1    Anderson, F.H.2    Bernstein, C.N.3
  • 14
    • 17144388945 scopus 로고    scopus 로고
    • Infliximab maintenance treatment reduces hospitalizations, surgeries, and procedures in fistulizing Crohn's disease
    • Lichtenstein GR, Yan S, Bala M, et al. Infliximab maintenance treatment reduces hospitalizations, surgeries, and procedures in fistulizing Crohn's disease. Gastroenterology. 2005; 128: 862-869.
    • (2005) Gastroenterology , vol.128 , pp. 862-869
    • Lichtenstein, G.R.1    Yan, S.2    Bala, M.3
  • 15
    • 32944461717 scopus 로고    scopus 로고
    • Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease
    • Rutgeerts P, Diamond RH, Bala M, et al. Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease. Gastrointest Endosc. 2006; 63: 433-442.
    • (2006) Gastrointest Endosc , vol.63 , pp. 433-442
    • Rutgeerts, P.1    Diamond, R.H.2    Bala, M.3
  • 16
    • 0032723990 scopus 로고    scopus 로고
    • Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine
    • D'Haens G, Geboes K, Rutgeerts P,. Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine. Gastrointest Endosc. 1999; 50: 667-671.
    • (1999) Gastrointest Endosc , vol.50 , pp. 667-671
    • D'Haens, G.1    Geboes, K.2    Rutgeerts, P.3
  • 17
    • 55449098725 scopus 로고    scopus 로고
    • Effects of adalimumab therapy on incidence of hospitalization and surgery in Crohn's disease: Result from the CHARM study
    • Feagan BG, Panaccione R, Sandborn WJ, et al. Effects of adalimumab therapy on incidence of hospitalization and surgery in Crohn's disease: result from the CHARM study. Gastroenterology. 2008; 135: 1493-1499.
    • (2008) Gastroenterology , vol.135 , pp. 1493-1499
    • Feagan, B.G.1    Panaccione, R.2    Sandborn, W.J.3
  • 18
    • 75449114677 scopus 로고    scopus 로고
    • Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease
    • Baert F, Moortgat L, Van Assche G, et al. Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease. Gastroenterology. 2010; 138: 463-468.
    • (2010) Gastroenterology , vol.138 , pp. 463-468
    • Baert, F.1    Moortgat, L.2    Van Assche, G.3
  • 19
    • 39449085441 scopus 로고    scopus 로고
    • Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: An open randomized trial
    • D'Haens G, Baert F, van Assche G, et al. Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomized trial. Lancet. 2008; 371: 660-667.
    • (2008) Lancet , vol.371 , pp. 660-667
    • D'Haens, G.1    Baert, F.2    Van Assche, G.3
  • 20
    • 0034735827 scopus 로고    scopus 로고
    • Comparison of etanercept and methotrexate in patients with early rheumatoid arthritis
    • Bathon JM, Martin RW, Fleischmann RM, et al. Comparison of etanercept and methotrexate in patients with early rheumatoid arthritis. N Engl J Med. 2000; 343: 1586-1593.
    • (2000) N Engl J Med , vol.343 , pp. 1586-1593
    • Bathon, J.M.1    Martin, R.W.2    Fleischmann, R.M.3
  • 21
    • 0036274944 scopus 로고    scopus 로고
    • Etanercept versus methotrexate in patients with early rheumatoid arthritis: Two-year radiographic and clinical outcomes
    • Genovese MC, Bathon JM, Martin RW, et al. Etanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomes. Arthritis Rheum. 2002; 46: 1443-1450.
    • (2002) Arthritis Rheum , vol.46 , pp. 1443-1450
    • Genovese, M.C.1    Bathon, J.M.2    Martin, R.W.3
  • 22
    • 8444239359 scopus 로고    scopus 로고
    • Active-controlled study of patients receiving infliximab for the treatment of rheumatoid arthritis of early onset study group. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial
    • St Clair EW, van der Heijde DM, Smolen JS, et al. Active-controlled study of patients receiving infliximab for the treatment of rheumatoid arthritis of early onset study group. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial. Arthritis Rheum. 2004; 50: 3432-3443.
    • (2004) Arthritis Rheum , vol.50 , pp. 3432-3443
    • St Clair, E.W.1    Van Der Heijde, D.M.2    Smolen, J.S.3
  • 23
    • 31044442965 scopus 로고    scopus 로고
    • The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment
    • Breedveld FC, Weisman MH, Kavanaugh AF, et al. The PREMIER study: a multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. Arthritis Rheum. 2006; 54: 26-37.
    • (2006) Arthritis Rheum , vol.54 , pp. 26-37
    • Breedveld, F.C.1    Weisman, M.H.2    Kavanaugh, A.F.3
  • 24
    • 34848887711 scopus 로고    scopus 로고
    • Early Crohn's disease shows high levels of remission to therapy with adalimumab. Subanalysis of CHARM
    • Schreiber S, Reinisch W, Colombel JF, et al. Early Crohn's disease shows high levels of remission to therapy with adalimumab. Subanalysis of CHARM. Gastroenterology. 2007; 132: A147.
    • (2007) Gastroenterology , vol.132
    • Schreiber, S.1    Reinisch, W.2    Colombel, J.F.3
  • 25
    • 77954423661 scopus 로고    scopus 로고
    • Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: An analysis of PRECiSE 2 randomized maintenance trial data
    • Schreiber S, Colombel JF, Bloomfield R, et al. Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: an analysis of PRECiSE 2 randomized maintenance trial data. Am J Gastroenterol. 2010; 105: 1574-1582.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1574-1582
    • Schreiber, S.1    Colombel, J.F.2    Bloomfield, R.3
  • 28
    • 0028109312 scopus 로고
    • Incidence of inflammatory bowel disease in northern France (1988-1990)
    • Gower-Rousseau C, Salomez JL, Dupas JL, et al. Incidence of inflammatory bowel disease in northern France (1988-1990). Gut. 1994; 35: 1433-1438.
    • (1994) Gut , vol.35 , pp. 1433-1438
    • Gower-Rousseau, C.1    Salomez, J.L.2    Dupas, J.L.3
  • 29
    • 2442713756 scopus 로고    scopus 로고
    • Opposite evolution in incidence of Crohn's disease and ulcerative colitis in northern France (1988-1999)
    • Molinie F, Gower-Rousseau C, Yzet T, et al. Opposite evolution in incidence of Crohn's disease and ulcerative colitis in northern France (1988-1999). Gut. 2004; 53: 843-848.
    • (2004) Gut , vol.53 , pp. 843-848
    • Molinie, F.1    Gower-Rousseau, C.2    Yzet, T.3
  • 30
    • 33646778482 scopus 로고    scopus 로고
    • The Montreal classification of inflammatory bowel disease: Controversies, consensus, and implications
    • Satsangi J, Silverberg MS, Vermeire S, et al. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut. 2006; 55: 749-753.
    • (2006) Gut , vol.55 , pp. 749-753
    • Satsangi, J.1    Silverberg, M.S.2    Vermeire, S.3
  • 31
    • 77955423917 scopus 로고    scopus 로고
    • Nutrional status and growth in pediatric Crohn's disease: A population based study
    • Vasseur F, Gower-Rousseau C, Vernier-Masouille G, et al. Nutrional status and growth in pediatric Crohn's disease: a population based study. Am J Gastroenterol. 2010; 105: 1893-1900.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1893-1900
    • Vasseur, F.1    Gower-Rousseau, C.2    Vernier-Masouille, G.3
  • 32
    • 0013504617 scopus 로고
    • Applied Statistics
    • 2nd ed. New York: Springer;. p.
    • Sachs L,. Applied Statistics, 2nd ed. A Handbook of Techniques. New York: Springer; 1982. p 333-337.
    • (1982) A Handbook of Techniques , pp. 333-337
    • Sachs, L.1
  • 33
    • 0017360990 scopus 로고
    • The measurement of observer agreement for categorical data
    • Landis JR, Koch GG, The measurement of observer agreement for categorical data. Biometrics. 1977; 33: 159-174.
    • (1977) Biometrics , vol.33 , pp. 159-174
    • Landis, J.R.1    Koch, G.G.2
  • 34
    • 33748147712 scopus 로고    scopus 로고
    • Corticosteroid therapy in the age of infliximab: Acute and 1-year outcomes in newly diagnosed children with Crohn's disease
    • Markowitz J, Hyams J, Mack D, et al Corticosteroid therapy in the age of infliximab: acute and 1-year outcomes in newly diagnosed children with Crohn's disease. Clin Gastroenterol Hepatol. 2006; 1124-1129.
    • (2006) Clin Gastroenterol Hepatol , pp. 1124-1129
    • Markowitz, J.1    Hyams, J.2    MacK, D.3
  • 35
    • 0035174914 scopus 로고    scopus 로고
    • Clinical outcome of Crohn's disease: Analysis according to the Vienna classification and clinical activity
    • Veloso FT, Ferreira JT, Barros L, et al. Clinical outcome of Crohn's disease: analysis according to the Vienna classification and clinical activity. Inflamm Bowel Dis. 2001; 7: 306-313.
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 306-313
    • Veloso, F.T.1    Ferreira, J.T.2    Barros, L.3
  • 36
    • 9144228789 scopus 로고    scopus 로고
    • Risk of early surgery for Crohn's disease: Implications for early treatment strategies
    • Sands BE, Arsenault JE, Rosen MJ, et al. Risk of early surgery for Crohn's disease: implications for early treatment strategies. Am J Gastroenterol. 2003; 98: 2712-2718.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2712-2718
    • Sands, B.E.1    Arsenault, J.E.2    Rosen, M.J.3
  • 37
    • 33746136945 scopus 로고    scopus 로고
    • Phenotype at diagnosis predicts recurrence rates in Crohn's disease
    • Wolters FL, Russel MG, Sijbrandij J, et al. Phenotype at diagnosis predicts recurrence rates in Crohn's disease. Gut. 2006; 55: 1124-1130.
    • (2006) Gut , vol.55 , pp. 1124-1130
    • Wolters, F.L.1    Russel, M.G.2    Sijbrandij, J.3
  • 38
    • 70349567522 scopus 로고    scopus 로고
    • Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological therapy are predictors of disease behaviour change in patients with Crohn's disease
    • Latakos PL, Czegledi Z, Szamosi T, et al. Perianal disease, small bowel disease, smoking, prior steroid or early azathioprine/biological therapy are predictors of disease behaviour change in patients with Crohn's disease. World J Gastroenterol. 2009; 15: 3504-3510.
    • (2009) World J Gastroenterol , vol.15 , pp. 3504-3510
    • Latakos, P.L.1    Czegledi, Z.2    Szamosi, T.3
  • 39
    • 77957346794 scopus 로고    scopus 로고
    • Risk factors associated with progression to intestinal complications of Crohn's disease in a population based cohort
    • Thia KT, Sandborn WJ, Harmsen WS, et al. Risk factors associated with progression to intestinal complications of Crohn's disease in a population based cohort. Gastroenterology. 2010; 139: 1147-1155.
    • (2010) Gastroenterology , vol.139 , pp. 1147-1155
    • Thia, K.T.1    Sandborn, W.J.2    Harmsen, W.S.3
  • 40
    • 62049083065 scopus 로고    scopus 로고
    • Clinical course of Crohn's disease first diagnosed at surgery for acute abdomen
    • Latella G, Cocco A, Angelucci E, et al. Clinical course of Crohn's disease first diagnosed at surgery for acute abdomen. Dig Dis Sci. 2009; 269-276.
    • (2009) Dig Dis Sci , pp. 269-276
    • Latella, G.1    Cocco, A.2    Angelucci, E.3
  • 41
    • 84876303024 scopus 로고    scopus 로고
    • Early surgery is not associated with poor prognosis in pediatric Crohn's disease: A population-based study
    • Boualit M, Julia Salleron J, Savoye G, et al. Early surgery is not associated with poor prognosis in pediatric Crohn's disease: a population-based study. Gastroenterology. 2011; 140 (Suppl 1): S-38.
    • (2011) Gastroenterology , vol.140 , Issue.SUPPL. 1
    • Boualit, M.1    Julia Salleron, J.2    Savoye, G.3
  • 42
    • 44949176312 scopus 로고    scopus 로고
    • Effect of early immunomodulator use in moderate to severe pediatric Crohn's disease
    • Punati J, Markowitz J, Lerer T, et al. Effect of early immunomodulator use in moderate to severe pediatric Crohn's disease. Inflamm Bowel Dis. 2008; 14: 949-954.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 949-954
    • Punati, J.1    Markowitz, J.2    Lerer, T.3
  • 43
    • 79955712974 scopus 로고    scopus 로고
    • Pediatric modification of the Montreal classification for inflammatory bowel disease: The Paris classification
    • Levine A, Griffiths A, Markowitz J, et al Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification. Inflamm Bowel Dis. 2011; 17: 1314-1321.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1314-1321
    • Levine, A.1    Griffiths, A.2    Markowitz, J.3
  • 44
    • 0036120291 scopus 로고    scopus 로고
    • Long term outcome of patients with active Crohn's disease exhibiting extensive and deep ulcerations at colonoscopy
    • Allez M, Lemann M, Bonnet J, et al. Long term outcome of patients with active Crohn's disease exhibiting extensive and deep ulcerations at colonoscopy. Am J Gastroenterol. 2002; 97: 947-953.
    • (2002) Am J Gastroenterol , vol.97 , pp. 947-953
    • Allez, M.1    Lemann, M.2    Bonnet, J.3
  • 45
    • 11144266571 scopus 로고    scopus 로고
    • Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype
    • Arnott ID, Landers CJ, Nimmo EJ, et al. Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype. Am J Gastroenterol. 2004; 99: 2376-2384.
    • (2004) Am J Gastroenterol , vol.99 , pp. 2376-2384
    • Arnott, I.D.1    Landers, C.J.2    Nimmo, E.J.3
  • 46
    • 52949145981 scopus 로고    scopus 로고
    • Increased immune reactivity predicts aggressive complicating Crohn's disease in children
    • Dubinski MC, Kugathasan S, Mei L, et al. Increased immune reactivity predicts aggressive complicating Crohn's disease in children. Clin Gastroenterol Hepatol. 2008; 6: 1105-1111.
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 1105-1111
    • Dubinski, M.C.1    Kugathasan, S.2    Mei, L.3
  • 47
    • 33644755927 scopus 로고    scopus 로고
    • Utility of serological markers in predicting the early occurrence of complications and surgery in pediatric Crohn's disease patients
    • Amre DK, Lu SE, Costea F, et al. Utility of serological markers in predicting the early occurrence of complications and surgery in pediatric Crohn's disease patients. Am J Gastroenterol. 2006; 101: 645-652.
    • (2006) Am J Gastroenterol , vol.101 , pp. 645-652
    • Amre, D.K.1    Lu, S.E.2    Costea, F.3
  • 48
    • 40949094473 scopus 로고    scopus 로고
    • New serological markers for inflammatory bowel disease are associated with earlier age at onset, complicated disease behaviour, risk for surgery, and NOD2/CARD15 genotype in a Hungarian IBD cohort
    • Papp M, Altorjay I, Dotan N, et al. New serological markers for inflammatory bowel disease are associated with earlier age at onset, complicated disease behaviour, risk for surgery, and NOD2/CARD15 genotype in a Hungarian IBD cohort. Am J Gastroenterol. 2008; 103: 665-681.
    • (2008) Am J Gastroenterol , vol.103 , pp. 665-681
    • Papp, M.1    Altorjay, I.2    Dotan, N.3
  • 49
    • 0036725827 scopus 로고    scopus 로고
    • Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
    • Abreu MT, Taylor KD, Lin YC, et al. Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease. Gastroenterology. 2002; 123: 679-688.
    • (2002) Gastroenterology , vol.123 , pp. 679-688
    • Abreu, M.T.1    Taylor, K.D.2    Lin, Y.C.3
  • 50
    • 13744264167 scopus 로고    scopus 로고
    • Variants of CARD15 are associated with an aggressive clinical course of Crohn's disease-an IG-IBD study
    • Annese V, Lombardi G, Perri F, et al. Variants of CARD15 are associated with an aggressive clinical course of Crohn's disease-an IG-IBD study. Am J Gastroenterol. 2005; 100: 84-92.
    • (2005) Am J Gastroenterol , vol.100 , pp. 84-92
    • Annese, V.1    Lombardi, G.2    Perri, F.3
  • 51
    • 27644562698 scopus 로고    scopus 로고
    • Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to structuring disease and higher rate of surgical recurrence
    • Alvarez-Lobos M, Arostegui JI, Sans M, et al. Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to structuring disease and higher rate of surgical recurrence. Ann Surg. 2005; 242: 693-700.
    • (2005) Ann Surg , vol.242 , pp. 693-700
    • Alvarez-Lobos, M.1    Arostegui, J.I.2    Sans, M.3
  • 52
    • 33748654515 scopus 로고    scopus 로고
    • Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of restonosis
    • Seiderer J, Schnitzler F, Brand S, et al. Homozygosity for the CARD15 frameshift mutation 1007fs is predictive of early onset of Crohn's disease with ileal stenosis, entero-enteral fistulas, and frequent need for surgical intervention with high risk of restonosis. Scand J Gastroenterol. 2006; 41: 1421-1432.
    • (2006) Scand J Gastroenterol , vol.41 , pp. 1421-1432
    • Seiderer, J.1    Schnitzler, F.2    Brand, S.3
  • 53
    • 11144279151 scopus 로고    scopus 로고
    • Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: A metaanalysis
    • Economou M, trikalinos TA, Loizou KT, et al. Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am J Gastroenterol. 2004; 99: 2393-2404.
    • (2004) Am J Gastroenterol , vol.99 , pp. 2393-2404
    • Economou, M.1    Trikalinos, T.A.2    Loizou, K.T.3
  • 54
    • 28844459843 scopus 로고    scopus 로고
    • Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD
    • Vermeire S, Pierik M, Hlavaty T, et al. Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD. Gastroenterology. 2005; 129: 1845-1853.
    • (2005) Gastroenterology , vol.129 , pp. 1845-1853
    • Vermeire, S.1    Pierik, M.2    Hlavaty, T.3
  • 55
    • 69249152654 scopus 로고    scopus 로고
    • Genetic profiling and prediction of disease course in Crohn's disease patients
    • Henckaerts L, Van Steen K, Verstreken I, et al. Genetic profiling and prediction of disease course in Crohn's disease patients. Clin Gastroenterol Hepatol. 2009; 7: 972-980.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 972-980
    • Henckaerts, L.1    Van Steen, K.2    Verstreken, I.3
  • 56
    • 61649123125 scopus 로고    scopus 로고
    • Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort
    • Weersma RK, Stokkers PC, van Bodegraven AA, et al. Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort. Gut. 2009; 58: 388-395.
    • (2009) Gut , vol.58 , pp. 388-395
    • Weersma, R.K.1    Stokkers, P.C.2    Van Bodegraven, A.A.3
  • 57
    • 34948854194 scopus 로고    scopus 로고
    • New serological markers in inflammatory bowel disease are associated with complicated disease behaviour
    • Ferrante M, Henckaerts L, Joossens M, et al. New serological markers in inflammatory bowel disease are associated with complicated disease behaviour. Gut. 2007; 56: 1394-1403.
    • (2007) Gut , vol.56 , pp. 1394-1403
    • Ferrante, M.1    Henckaerts, L.2    Joossens, M.3
  • 58
    • 78650077217 scopus 로고    scopus 로고
    • Real-time tool to display the predicted disease course and treatment response for children with Crohn's disease
    • Siegel CA, Siegel LS, Hyams JS, et al. Real-time tool to display the predicted disease course and treatment response for children with Crohn's disease. Inflamm Bowel Dis. 2011; 17: 30-38.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 30-38
    • Siegel, C.A.1    Siegel, L.S.2    Hyams, J.S.3
  • 59
    • 84876344280 scopus 로고    scopus 로고
    • Disability in inflammatory bowel disease: Developing Icf core sets for patients with IBD based on the WHO international classification of functioning, disability and health
    • Peyrin-Biroulet L, Cieza A, Sandborn WJ, et al. Disability in inflammatory bowel disease: developing Icf core sets for patients with IBD based on the WHO international classification of functioning, disability and health. Gastroenterology. 2011; 140 (Suppl 1): S424.
    • (2011) Gastroenterology , vol.140 , Issue.SUPPL. 1
    • Peyrin-Biroulet, L.1    Cieza, A.2    Sandborn, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.