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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 21, 2012, Pages 6577-6579

Downregulation of mdr1 and abcg2 genes is a mechanism of inhibition of efflux pumps mediated by polymeric amphiphiles

(4) Cuestas, María L a,b Castillo, Amalia I a,b Sosnik, Alejandro a,b Mathet, Verónica L a,b

a UNIVERSIDAD DE BUENOS AIRES (Argentina)

b National Science Research Council CONICET (Argentina)

Author keywords

Inhibition of ATP binding cassette pumps; mdr1, mpr1 and abcg2 genes; Poloxamines

Indexed keywords

ABC TRANSPORTER; AMPHOPHILE; BREAST CANCER RESISTANCE PROTEIN; COPOLYMER; MACROGOL; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; POLOXAMINE 908;

ARTICLE; CANCER CELL CULTURE; DOWN REGULATION; HUMAN; HUMAN CELL; HYDROPHILICITY; LIPOPHILICITY; MOLECULAR WEIGHT; MULTIDRUG RESISTANCE; NEOPLASM; TEMPERATURE;

AMINES; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TUMOR; DOWN-REGULATION; HUMANS; NEOPLASM PROTEINS; OXAMIC ACID; P-GLYCOPROTEIN; POLYMERASE CHAIN REACTION; SURFACE-ACTIVE AGENTS;

EID: 84867572279 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.09.012 Document Type: Article

Times cited : (48)

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