Population pharmacokinetics and Bayesian estimation of cyclosporine in a Tunisian population of hematopoietic stem cell transplant recipient

European Journal of Clinical Pharmacology

Volumn 68, Issue 11, 2012, Pages 1517-1524

  Eljebari, Hanene ^a   Gaies, Emna ^a,b   Fradj, Nadia Ben ^a,b   Jebabli, Nadia ^a,b   Salouage, Issam ^a,b   Trabelsi, Sameh ^a,b   Lakhal, Mohamed ^a,b   Klouz, Anis ^a,b  

^a Centre National de Pharmacovigilance   (Tunisia)

^b UNIVERSITY OF TUNIS EL MANAR   (Tunisia)

Author keywords

Bayesian estimation; Cyclosporine; Hematopoietic stem cell transplantation; NONMEM; Population pharmacokinetics

Indexed keywords

ACICLOVIR; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; AMOXICILLIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CREATININE; CYCLOSPORIN; FLUCONAZOLE; SANDIMMUM; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; AREA UNDER THE CURVE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BAYESIAN LEARNING; BILIRUBIN BLOOD LEVEL; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG ABSORPTION; DRUG CLEARANCE; DRUG DISPOSITION; DRUG HALF LIFE; FEMALE; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MALE; MAXIMUM PLASMA CONCENTRATION; PHARMACOKINETICS; POPULATION RESEARCH; PRIORITY JOURNAL; SCHOOL CHILD; TIME TO MAXIMUM PLASMA CONCENTRATION; TUNISIA;

ADOLESCENT; ADULT; BAYES THEOREM; CHILD; CYCLOSPORINE; DRUG MONITORING; FEMALE; GRAFT VS HOST DISEASE; HALF-LIFE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTESTINAL ABSORPTION; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; MODELS, BIOLOGICAL; REPRODUCIBILITY OF RESULTS; TUNISIA; YOUNG ADULT;

EID: 84867570998     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-012-1275-9     Document Type: Article

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